DK217588D0 - 17beta-(cyclopropylamino)-androst-5-en-3beta-olderivater, deres fremstilling og anvendelse som laegemidler - Google Patents
17beta-(cyclopropylamino)-androst-5-en-3beta-olderivater, deres fremstilling og anvendelse som laegemidlerInfo
- Publication number
- DK217588D0 DK217588D0 DK217588A DK217588A DK217588D0 DK 217588 D0 DK217588 D0 DK 217588D0 DK 217588 A DK217588 A DK 217588A DK 217588 A DK217588 A DK 217588A DK 217588 D0 DK217588 D0 DK 217588D0
- Authority
- DK
- Denmark
- Prior art keywords
- androst
- cyclopropylamino
- 17beta
- 3beta
- older
- Prior art date
Links
- -1 CYCLOPROPYLAMINO Chemical class 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- LYFPAZBMEUSVNA-UHFFFAOYSA-N (10R)-3c-Hydroxy-10r.13c-dimethyl-(8cH.9tH.14tH)-Delta5-tetradecahydro-1H-cyclopenta[a]phenanthren Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCCC1(C)CC2 LYFPAZBMEUSVNA-UHFFFAOYSA-N 0.000 abstract 1
- LYFPAZBMEUSVNA-DYKIIFRCSA-N (3s,8s,9s,10r,13s,14s)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-ol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 LYFPAZBMEUSVNA-DYKIIFRCSA-N 0.000 abstract 1
- 239000003098 androgen Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 150000002466 imines Chemical class 0.000 abstract 1
- 230000003637 steroidlike Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4117287A | 1987-04-22 | 1987-04-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK217588D0 true DK217588D0 (da) | 1988-04-21 |
| DK217588A DK217588A (da) | 1988-10-23 |
Family
ID=21915133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK217588A DK217588A (da) | 1987-04-22 | 1988-04-21 | 17beta-(cyclopropylamino)-androst-5-en-3beta-olderivater, deres fremstilling og anvendelse som laegemidler |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0288053B1 (da) |
| JP (1) | JP2711672B2 (da) |
| KR (1) | KR960015037B1 (da) |
| CN (1) | CN88102176A (da) |
| AT (1) | ATE67211T1 (da) |
| AU (1) | AU606677B2 (da) |
| CA (1) | CA1326234C (da) |
| DE (1) | DE3864725D1 (da) |
| DK (1) | DK217588A (da) |
| ES (1) | ES2038712T3 (da) |
| FI (1) | FI88397C (da) |
| GR (1) | GR3002713T3 (da) |
| HU (1) | HU198511B (da) |
| IL (1) | IL86139A (da) |
| NO (1) | NO169346C (da) |
| NZ (1) | NZ224288A (da) |
| PH (1) | PH24090A (da) |
| PT (1) | PT87294B (da) |
| ZA (1) | ZA882717B (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4891367A (en) * | 1987-04-22 | 1990-01-02 | Merrell Dow Pharmaceuticals Inc. | 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
| US4954488A (en) * | 1989-06-14 | 1990-09-04 | Merrell Dow Pharmaceuticals Inc. | Method of treating hyperaldosteronism using 17β-cyclopropylaminoandrostene derivatives |
| US4966898A (en) * | 1989-08-15 | 1990-10-30 | Merrell Dow Pharmaceuticals Inc. | 4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
| US5209926A (en) * | 1990-06-12 | 1993-05-11 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
| US5124154A (en) * | 1990-06-12 | 1992-06-23 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
| US5256408A (en) * | 1990-06-12 | 1993-10-26 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
| US5252319A (en) * | 1990-06-12 | 1993-10-12 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
| CZ287434B6 (en) * | 1992-03-31 | 2000-11-15 | British Tech Group | Use of steroids, substituted in position 17, steroids functioning as carcinostatics and pharmaceutical preparation containing thereof |
| US5604213A (en) * | 1992-03-31 | 1997-02-18 | British Technology Group Limited | 17-substituted steroids useful in cancer treatment |
| US5486511A (en) * | 1993-05-25 | 1996-01-23 | Merrell Dow Pharmaceuticals Inc. | 4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase |
| JP3753971B2 (ja) | 2000-11-17 | 2006-03-08 | 武田薬品工業株式会社 | 新規イミダゾール誘導体、その製造法および用途 |
| DE60144246D1 (de) | 2000-11-20 | 2011-04-28 | Takeda Pharmaceutical | Imidazolderivate, verfahren zu deren herstellung und deren verwendung |
| AU2002221080A1 (en) | 2000-12-08 | 2002-06-18 | Masami Kusaka | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparingthe same and use thereof |
| UY32730A (es) | 2009-06-26 | 2011-01-31 | Novartis Ag | Inhibidores de cyp17 |
| KR101926320B1 (ko) | 2010-08-04 | 2018-12-06 | 펠피큐어 파마슈티걸즈 아이엔씨 | 전립선 암종의 치료를 위한 병용 요법 |
| EP2627648A1 (en) | 2010-09-16 | 2013-08-21 | Novartis AG | 17aHYDROXYLASE/C17,20-LYASE INHIBITORS |
| MX359399B (es) | 2011-04-28 | 2018-09-27 | Novartis Ag | Inhibidores de 17alfa-hidroxilasa/c17-20-liasa. |
| WO2014158875A1 (en) | 2013-03-14 | 2014-10-02 | Pellficure Pharmaceuticals Inc. | Novel therapy for prostate carcinoma |
| CA2960750A1 (en) | 2014-09-12 | 2016-03-17 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
| WO2018080933A1 (en) | 2016-10-24 | 2018-05-03 | Pellficure Pharmaceuticals Inc. | Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL302932A (da) * | 1962-12-31 | |||
| US4891367A (en) * | 1987-04-22 | 1990-01-02 | Merrell Dow Pharmaceuticals Inc. | 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
-
1988
- 1988-04-18 ZA ZA882717A patent/ZA882717B/xx unknown
- 1988-04-18 CA CA000564364A patent/CA1326234C/en not_active Expired - Fee Related
- 1988-04-18 AU AU14719/88A patent/AU606677B2/en not_active Ceased
- 1988-04-18 NZ NZ224288A patent/NZ224288A/xx unknown
- 1988-04-19 PH PH36817A patent/PH24090A/en unknown
- 1988-04-20 IL IL86139A patent/IL86139A/xx unknown
- 1988-04-21 NO NO881746A patent/NO169346C/no unknown
- 1988-04-21 ES ES198888106397T patent/ES2038712T3/es not_active Expired - Lifetime
- 1988-04-21 JP JP63096969A patent/JP2711672B2/ja not_active Expired - Fee Related
- 1988-04-21 DK DK217588A patent/DK217588A/da not_active Application Discontinuation
- 1988-04-21 CN CN198888102176A patent/CN88102176A/zh active Pending
- 1988-04-21 EP EP88106397A patent/EP0288053B1/en not_active Expired - Lifetime
- 1988-04-21 FI FI881877A patent/FI88397C/fi not_active IP Right Cessation
- 1988-04-21 HU HU882029A patent/HU198511B/hu not_active IP Right Cessation
- 1988-04-21 PT PT87294A patent/PT87294B/pt not_active IP Right Cessation
- 1988-04-21 KR KR1019880004512A patent/KR960015037B1/ko not_active Expired - Fee Related
- 1988-04-21 AT AT88106397T patent/ATE67211T1/de not_active IP Right Cessation
- 1988-04-21 DE DE8888106397T patent/DE3864725D1/de not_active Expired - Fee Related
-
1991
- 1991-09-12 GR GR91401315T patent/GR3002713T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT47307A (en) | 1989-02-28 |
| KR880012633A (ko) | 1988-11-28 |
| FI881877A0 (fi) | 1988-04-21 |
| NO169346C (no) | 1992-06-10 |
| FI88397B (fi) | 1993-01-29 |
| KR960015037B1 (ko) | 1996-10-24 |
| PT87294B (pt) | 1992-08-31 |
| ES2038712T3 (es) | 1993-08-01 |
| PT87294A (pt) | 1988-05-01 |
| DE3864725D1 (de) | 1991-10-17 |
| PH24090A (en) | 1990-03-05 |
| EP0288053A1 (en) | 1988-10-26 |
| EP0288053B1 (en) | 1991-09-11 |
| ZA882717B (en) | 1988-10-17 |
| AU1471988A (en) | 1988-10-27 |
| CA1326234C (en) | 1994-01-18 |
| JPS63284195A (ja) | 1988-11-21 |
| FI88397C (fi) | 1993-05-10 |
| NO881746L (no) | 1988-10-24 |
| NZ224288A (en) | 1989-12-21 |
| IL86139A (en) | 1993-02-21 |
| CN88102176A (zh) | 1988-11-23 |
| NO169346B (no) | 1992-03-02 |
| DK217588A (da) | 1988-10-23 |
| HU198511B (en) | 1989-10-30 |
| ATE67211T1 (de) | 1991-09-15 |
| IL86139A0 (en) | 1988-11-15 |
| FI881877A7 (fi) | 1988-10-23 |
| JP2711672B2 (ja) | 1998-02-10 |
| GR3002713T3 (en) | 1993-01-25 |
| AU606677B2 (en) | 1991-02-14 |
| NO881746D0 (no) | 1988-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |