ATE125811T1 - 7-(diphenylmethyl)oxy-9a-methoxymitosan, seine herstellung und verwendung. - Google Patents

7-(diphenylmethyl)oxy-9a-methoxymitosan, seine herstellung und verwendung.

Info

Publication number
ATE125811T1
ATE125811T1 AT91103504T AT91103504T ATE125811T1 AT E125811 T1 ATE125811 T1 AT E125811T1 AT 91103504 T AT91103504 T AT 91103504T AT 91103504 T AT91103504 T AT 91103504T AT E125811 T1 ATE125811 T1 AT E125811T1
Authority
AT
Austria
Prior art keywords
methoxymitosane
oxy
ethylamino
diphenylmethyl
pyridyldithio
Prior art date
Application number
AT91103504T
Other languages
English (en)
Inventor
Daniel A Benigni
Kenton L Shultis
Henry She Lai Wong
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE125811T1 publication Critical patent/ATE125811T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
AT91103504T 1990-03-08 1991-03-07 7-(diphenylmethyl)oxy-9a-methoxymitosan, seine herstellung und verwendung. ATE125811T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/491,380 US5075454A (en) 1990-03-08 1990-03-08 7-(diphenylmethyl)oxy-9a-methoxymitosane

Publications (1)

Publication Number Publication Date
ATE125811T1 true ATE125811T1 (de) 1995-08-15

Family

ID=23951969

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91103504T ATE125811T1 (de) 1990-03-08 1991-03-07 7-(diphenylmethyl)oxy-9a-methoxymitosan, seine herstellung und verwendung.

Country Status (18)

Country Link
US (2) US5075454A (de)
EP (1) EP0445813B1 (de)
JP (1) JP2991348B2 (de)
KR (1) KR0152495B1 (de)
AT (1) ATE125811T1 (de)
AU (1) AU630022B2 (de)
CA (1) CA2037687C (de)
CY (1) CY1885A (de)
DE (1) DE69111640T2 (de)
DK (1) DK0445813T3 (de)
ES (1) ES2077091T3 (de)
FI (1) FI95260C (de)
GR (1) GR3017040T3 (de)
HK (1) HK4496A (de)
IE (1) IE68314B1 (de)
PT (1) PT96966B (de)
TW (1) TW219938B (de)
ZA (1) ZA911672B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495348B1 (en) * 1993-10-07 2002-12-17 Regents Of The University Of Minnesota Mitomycin biosynthetic gene cluster
US6524812B1 (en) 1993-10-07 2003-02-25 Regents Of The University Of Minnesota Genes encoding resistance to DNA alkylating agents
US5703111A (en) * 1996-01-05 1997-12-30 Bristol-Myers Squibb Company Stable injectable formulation of BMY-25067
CA2208690A1 (en) * 1996-09-06 1998-03-06 James Robert Mccandless Package for compounding rubber, compounded rubber and tire having tread thereof
KR20180003312U (ko) 2017-05-16 2018-11-26 남송학 구근줄기 절단 및 선별 배출장치

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3306821A (en) * 1962-09-04 1967-02-28 Upjohn Co Porfiromycin derivatives and method of making same
US4059573A (en) * 1973-08-01 1977-11-22 Glaxo Laboratories Limited Extraction of N-blocked amino acids from aqueous media
JPS5840088A (ja) * 1981-09-04 1983-03-08 Kyowa Hakko Kogyo Co Ltd 発酵法によるマイトマイシンａの製造法
EP0116208B1 (de) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Mitomycin-Analoge
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
US4691023A (en) * 1984-02-24 1987-09-01 Bristol-Myers Company Amino disulfides
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
US4814445A (en) * 1984-09-04 1989-03-21 Bristol-Myers Company Process for preparing mitomycin analogs
US4866189A (en) * 1985-04-12 1989-09-12 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US4720543A (en) * 1985-06-06 1988-01-19 Georgetown University 1a-7-substituted derivatives of mitomycin and uses thereof
US5023253A (en) * 1987-12-21 1991-06-11 University Patents, Inc. 6-substituted mitomycin analogs

Also Published As

Publication number Publication date
FI911184A (fi) 1991-09-09
IE910762A1 (en) 1991-09-11
DE69111640T2 (de) 1996-01-25
PT96966B (pt) 1998-07-31
TW219938B (de) 1994-02-01
AU7269891A (en) 1991-09-12
ES2077091T3 (es) 1995-11-16
CA2037687A1 (en) 1991-09-09
DE69111640D1 (de) 1995-09-07
KR910016754A (ko) 1991-11-05
EP0445813A1 (de) 1991-09-11
JP2991348B2 (ja) 1999-12-20
KR0152495B1 (en) 1998-10-15
FI95260B (fi) 1995-09-29
EP0445813B1 (de) 1995-08-02
FI911184A0 (fi) 1991-03-08
GR3017040T3 (en) 1995-11-30
CA2037687C (en) 2001-10-30
JPH04211688A (ja) 1992-08-03
PT96966A (pt) 1991-10-31
IE68314B1 (en) 1996-06-12
AU630022B2 (en) 1992-10-15
US5075454A (en) 1991-12-24
FI95260C (fi) 1996-01-10
ZA911672B (en) 1991-11-27
CY1885A (en) 1996-04-05
DK0445813T3 (da) 1995-09-18
US5352798A (en) 1994-10-04
HK4496A (en) 1996-01-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee