ATE121388T1 - 3- oder 4-substituierte oxotremorin-derivate. - Google Patents
3- oder 4-substituierte oxotremorin-derivate.Info
- Publication number
- ATE121388T1 ATE121388T1 AT90101248T AT90101248T ATE121388T1 AT E121388 T1 ATE121388 T1 AT E121388T1 AT 90101248 T AT90101248 T AT 90101248T AT 90101248 T AT90101248 T AT 90101248T AT E121388 T1 ATE121388 T1 AT E121388T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- substituted
- oxotremorine
- derivatives
- oxotremorine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/300,447 US4937235A (en) | 1989-01-23 | 1989-01-23 | 3- or 4-substituted oxotremorine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE121388T1 true ATE121388T1 (de) | 1995-05-15 |
Family
ID=23159138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90101248T ATE121388T1 (de) | 1989-01-23 | 1990-01-22 | 3- oder 4-substituierte oxotremorin-derivate. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US4937235A (de) |
| EP (1) | EP0381984B1 (de) |
| JP (1) | JP2894358B2 (de) |
| AT (1) | ATE121388T1 (de) |
| AU (1) | AU622517B2 (de) |
| CA (1) | CA2008107C (de) |
| DE (1) | DE69018659T2 (de) |
| DK (1) | DK0381984T3 (de) |
| ES (1) | ES2070934T3 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089518A (en) * | 1989-01-23 | 1992-02-18 | American Cyanamid Company | 3- or 4-substituted oxotremorine derivatives and a method of treating cholinergic dysfunction therewith |
| JP2834501B2 (ja) * | 1989-11-25 | 1998-12-09 | 鐘淵化学工業株式会社 | ３，４―エポキシ酪酸エステルの製法および中間体 |
| US5550257A (en) * | 1991-04-24 | 1996-08-27 | American Cyanamid Company | Substituted oxotremorine derivatives |
| US5356885A (en) * | 1991-04-24 | 1994-10-18 | American Cyanamid Company | Substituted oxotremorine derivatives and pharmaceutical use thereof |
| US5346910A (en) * | 1992-06-03 | 1994-09-13 | American Cyanamid Company | Maleimide derivatives of oxotremorine |
| US5932745A (en) * | 1997-07-30 | 1999-08-03 | American Home Products Corporation | Process for converting propargylic amine-N-oxides to enaminones |
| KR100295740B1 (ko) | 1998-09-17 | 2001-11-05 | 박영구 | N-치환된-하이드록시고리화알킬아민유도체의제조방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1245743A (en) * | 1967-11-09 | 1971-09-08 | Astra Ab | Alkynyl lactams |
| US3856790A (en) | 1970-01-06 | 1974-12-24 | American Home Prod | Cyclic amides of 1,4-diaminobut-2-yne |
| EP0009326A3 (de) * | 1978-08-30 | 1980-04-16 | Pfizer Limited | Pyrrolylketo- und Aminosäuren und deren Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
| GR78370B (de) * | 1981-12-24 | 1984-09-26 | Delalande Sa | |
| US4847284A (en) * | 1988-03-23 | 1989-07-11 | Merck & Co., Inc. | Antifungal fermentation product and derivatives and compositions thereof |
| DE3835291A1 (de) * | 1988-04-19 | 1989-11-02 | Bayer Ag | 1,3-disubstituierte pyrrolidine |
-
1989
- 1989-01-23 US US07/300,447 patent/US4937235A/en not_active Expired - Fee Related
-
1990
- 1990-01-19 CA CA002008107A patent/CA2008107C/en not_active Expired - Fee Related
- 1990-01-19 JP JP2008533A patent/JP2894358B2/ja not_active Expired - Lifetime
- 1990-01-22 AT AT90101248T patent/ATE121388T1/de active
- 1990-01-22 EP EP90101248A patent/EP0381984B1/de not_active Expired - Lifetime
- 1990-01-22 AU AU48684/90A patent/AU622517B2/en not_active Ceased
- 1990-01-22 ES ES90101248T patent/ES2070934T3/es not_active Expired - Lifetime
- 1990-01-22 DE DE69018659T patent/DE69018659T2/de not_active Expired - Fee Related
- 1990-01-22 DK DK90101248.4T patent/DK0381984T3/da active
- 1990-02-20 US US07/481,924 patent/US4952600A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU622517B2 (en) | 1992-04-09 |
| DE69018659D1 (de) | 1995-05-24 |
| US4952600A (en) | 1990-08-28 |
| DE69018659T2 (de) | 1996-01-18 |
| US4937235A (en) | 1990-06-26 |
| EP0381984B1 (de) | 1995-04-19 |
| JP2894358B2 (ja) | 1999-05-24 |
| DK0381984T3 (da) | 1995-05-08 |
| ES2070934T3 (es) | 1995-06-16 |
| AU4868490A (en) | 1990-07-26 |
| CA2008107A1 (en) | 1990-07-23 |
| JPH02229155A (ja) | 1990-09-11 |
| EP0381984A1 (de) | 1990-08-16 |
| CA2008107C (en) | 1996-08-13 |
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