ES2070934T3 - Derivados de oxotremorina 3- o 4-sustituidos. - Google Patents
Derivados de oxotremorina 3- o 4-sustituidos.Info
- Publication number
- ES2070934T3 ES2070934T3 ES90101248T ES90101248T ES2070934T3 ES 2070934 T3 ES2070934 T3 ES 2070934T3 ES 90101248 T ES90101248 T ES 90101248T ES 90101248 T ES90101248 T ES 90101248T ES 2070934 T3 ES2070934 T3 ES 2070934T3
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- substituted
- derivatives
- oxotremorina
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Abstract
ESTE DESCUBRIMIENTO DESCRIBE NUEVOS DERIVADOS DE 3 O 4 SUSTITUIDA OXOTREMORINA TENIENDO GRUPOS AZUFRE U OXIGENO POLAR SUSTITUIDOS. LOS COMPUESTOS TIENEN ACTIVIDAD COMO IMPULSORES NERVIOSOS. TAMBIEN SE DESCUBREN METODOS PARA TRATAR ENFERMEDADES DEL SISTEMA NERVIOSO CENTRAL EN MAMIFEROS EMPLEANDO LOS COMPUESTOS, PREPARACIONES FARMACEUTICAS CONTENIENDO LOS COMPUESTOS Y PROCESOS PARA LA PRODUCCION DE LOS COMPUESTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/300,447 US4937235A (en) | 1989-01-23 | 1989-01-23 | 3- or 4-substituted oxotremorine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2070934T3 true ES2070934T3 (es) | 1995-06-16 |
Family
ID=23159138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90101248T Expired - Lifetime ES2070934T3 (es) | 1989-01-23 | 1990-01-22 | Derivados de oxotremorina 3- o 4-sustituidos. |
Country Status (9)
Country | Link |
---|---|
US (2) | US4937235A (es) |
EP (1) | EP0381984B1 (es) |
JP (1) | JP2894358B2 (es) |
AT (1) | ATE121388T1 (es) |
AU (1) | AU622517B2 (es) |
CA (1) | CA2008107C (es) |
DE (1) | DE69018659T2 (es) |
DK (1) | DK0381984T3 (es) |
ES (1) | ES2070934T3 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089518A (en) * | 1989-01-23 | 1992-02-18 | American Cyanamid Company | 3- or 4-substituted oxotremorine derivatives and a method of treating cholinergic dysfunction therewith |
JP2834501B2 (ja) * | 1989-11-25 | 1998-12-09 | 鐘淵化学工業株式会社 | 3,4―エポキシ酪酸エステルの製法および中間体 |
US5550257A (en) * | 1991-04-24 | 1996-08-27 | American Cyanamid Company | Substituted oxotremorine derivatives |
US5356885A (en) * | 1991-04-24 | 1994-10-18 | American Cyanamid Company | Substituted oxotremorine derivatives and pharmaceutical use thereof |
US5346910A (en) * | 1992-06-03 | 1994-09-13 | American Cyanamid Company | Maleimide derivatives of oxotremorine |
US5932745A (en) * | 1997-07-30 | 1999-08-03 | American Home Products Corporation | Process for converting propargylic amine-N-oxides to enaminones |
KR100295740B1 (ko) | 1998-09-17 | 2001-11-05 | 박영구 | N-치환된-하이드록시고리화알킬아민유도체의제조방법 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1245743A (en) * | 1967-11-09 | 1971-09-08 | Astra Ab | Alkynyl lactams |
US3856790A (en) | 1970-01-06 | 1974-12-24 | American Home Prod | Cyclic amides of 1,4-diaminobut-2-yne |
EP0009326A3 (en) * | 1978-08-30 | 1980-04-16 | Pfizer Limited | Pyrrolyl keto and amino acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them |
GR78370B (es) * | 1981-12-24 | 1984-09-26 | Delalande Sa | |
US4847284A (en) * | 1988-03-23 | 1989-07-11 | Merck & Co., Inc. | Antifungal fermentation product and derivatives and compositions thereof |
DE3835291A1 (de) * | 1988-04-19 | 1989-11-02 | Bayer Ag | 1,3-disubstituierte pyrrolidine |
-
1989
- 1989-01-23 US US07/300,447 patent/US4937235A/en not_active Expired - Fee Related
-
1990
- 1990-01-19 CA CA002008107A patent/CA2008107C/en not_active Expired - Fee Related
- 1990-01-19 JP JP2008533A patent/JP2894358B2/ja not_active Expired - Lifetime
- 1990-01-22 DK DK90101248.4T patent/DK0381984T3/da active
- 1990-01-22 EP EP90101248A patent/EP0381984B1/en not_active Expired - Lifetime
- 1990-01-22 DE DE69018659T patent/DE69018659T2/de not_active Expired - Fee Related
- 1990-01-22 ES ES90101248T patent/ES2070934T3/es not_active Expired - Lifetime
- 1990-01-22 AT AT90101248T patent/ATE121388T1/de active
- 1990-01-22 AU AU48684/90A patent/AU622517B2/en not_active Ceased
- 1990-02-20 US US07/481,924 patent/US4952600A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US4952600A (en) | 1990-08-28 |
EP0381984B1 (en) | 1995-04-19 |
CA2008107C (en) | 1996-08-13 |
JP2894358B2 (ja) | 1999-05-24 |
CA2008107A1 (en) | 1990-07-23 |
JPH02229155A (ja) | 1990-09-11 |
ATE121388T1 (de) | 1995-05-15 |
DK0381984T3 (da) | 1995-05-08 |
AU622517B2 (en) | 1992-04-09 |
DE69018659T2 (de) | 1996-01-18 |
US4937235A (en) | 1990-06-26 |
DE69018659D1 (de) | 1995-05-24 |
EP0381984A1 (en) | 1990-08-16 |
AU4868490A (en) | 1990-07-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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