ATE119898T1 - Nmda-blockierende verbindungen, pharmazeutische präparate, deren herstellung und verwendung. - Google Patents

Nmda-blockierende verbindungen, pharmazeutische präparate, deren herstellung und verwendung.

Info

Publication number
ATE119898T1
ATE119898T1 AT90312147T AT90312147T ATE119898T1 AT E119898 T1 ATE119898 T1 AT E119898T1 AT 90312147 T AT90312147 T AT 90312147T AT 90312147 T AT90312147 T AT 90312147T AT E119898 T1 ATE119898 T1 AT E119898T1
Authority
AT
Austria
Prior art keywords
designates
preparation
chained
straight
nmda
Prior art date
Application number
AT90312147T
Other languages
English (en)
Inventor
Yoel Kloog
Jeffery J Feigenbaum
Raphael Mechoulam
Mordechai Sokolowsky
Simon Benita
Original Assignee
Yissum Res Dev Co
Univ Ramot
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co, Univ Ramot filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE119898T1 publication Critical patent/ATE119898T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT90312147T 1989-11-07 1990-11-06 Nmda-blockierende verbindungen, pharmazeutische präparate, deren herstellung und verwendung. ATE119898T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL9223889A IL92238A (en) 1989-11-07 1989-11-07 ADMN blocking product containing tetrahydrocannabinol history, several new tetrahydrocannabinol histories and process for their preparation

Publications (1)

Publication Number Publication Date
ATE119898T1 true ATE119898T1 (de) 1995-04-15

Family

ID=11060554

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90312147T ATE119898T1 (de) 1989-11-07 1990-11-06 Nmda-blockierende verbindungen, pharmazeutische präparate, deren herstellung und verwendung.

Country Status (11)

Country Link
EP (1) EP0427518B1 (de)
JP (1) JPH0768235B2 (de)
KR (1) KR950005914B1 (de)
AT (1) ATE119898T1 (de)
AU (1) AU631262B2 (de)
CA (1) CA2029419C (de)
DE (1) DE69017839T2 (de)
DK (1) DK0427518T3 (de)
ES (1) ES2071786T3 (de)
IL (1) IL92238A (de)
ZA (1) ZA908914B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
JP2002514184A (ja) 1996-09-27 2002-05-14 ギルフォード ファーマスーティカルズ インコーポレイテッド Ｎａａｌａｄアーゼ組成物ならびに動物におけるグルタメート異常を治療する方法および神経活性をもたらす方法
DE19706903A1 (de) 1997-02-21 1998-08-27 Bayer Ag Verwendung von bekannten Agonisten des zentralen Cannabinoid-Rezeptors CB 1
AU743788B2 (en) * 1997-05-07 2002-02-07 Unimed Pharmaceuticals, Inc. Method of improving disturbed behavior and elevating mood in humans
ATE367809T1 (de) 1998-04-21 2007-08-15 Us Health Cannabinoiden als antioxidantien und neuroschützende mittel
ZA200802767B (en) 2005-09-29 2009-09-30 Amr Technology Inc Process for production of delta-9-tetrahydrocannabinol
DE102015112092B4 (de) 2015-07-24 2022-03-10 Beko Technologies Gmbh Öl/Wasser-Trennvorrichtung mit Druckluftbeaufschlagung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48824A (en) * 1976-01-12 1980-05-30 Yissum Res Dev Co Pharmaceutical compositions containing (3s,js) tetrahydrocanabinol derivatives and some novel compounds of this type
US4133819A (en) * 1977-06-17 1979-01-09 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4209520A (en) * 1977-06-17 1980-06-24 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
IL80411A (en) * 1986-10-24 1991-08-16 Raphael Mechoulam Preparation of dibenzopyranol derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IL92238A (en) 1995-07-31
CA2029419A1 (en) 1991-05-08
EP0427518B1 (de) 1995-03-15
IL92238A0 (de) 1990-07-26
EP0427518A1 (de) 1991-05-15
AU631262B2 (en) 1992-11-19
ES2071786T3 (es) 1995-07-01
KR950005914B1 (ko) 1995-06-07
CA2029419C (en) 2004-05-25
DE69017839T2 (de) 1995-08-31
ZA908914B (en) 1991-09-25
JPH0768235B2 (ja) 1995-07-26
DE69017839D1 (de) 1995-04-20
KR910009687A (ko) 1991-06-28
JPH03209377A (ja) 1991-09-12
AU6583490A (en) 1991-05-30
DK0427518T3 (da) 1995-07-24

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee