ATE119042T1 - Verwendung eines viralen glykoprotein-impstoffes für intranasale immunisierung gegen eine virusinfektion. - Google Patents

Verwendung eines viralen glykoprotein-impstoffes für intranasale immunisierung gegen eine virusinfektion.

Info

Publication number
ATE119042T1
ATE119042T1 AT88905073T AT88905073T ATE119042T1 AT E119042 T1 ATE119042 T1 AT E119042T1 AT 88905073 T AT88905073 T AT 88905073T AT 88905073 T AT88905073 T AT 88905073T AT E119042 T1 ATE119042 T1 AT E119042T1
Authority
AT
Austria
Prior art keywords
virus infection
immunization against
viral glycoprotein
against virus
intranasal immunization
Prior art date
Application number
AT88905073T
Other languages
English (en)
Inventor
Richard W Compans
Ranjit Ray
Original Assignee
Secretech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21945570&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE119042(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Secretech Inc filed Critical Secretech Inc
Application granted granted Critical
Publication of ATE119042T1 publication Critical patent/ATE119042T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AT88905073T 1987-05-05 1988-05-04 Verwendung eines viralen glykoprotein-impstoffes für intranasale immunisierung gegen eine virusinfektion. ATE119042T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4682087A 1987-05-05 1987-05-05

Publications (1)

Publication Number Publication Date
ATE119042T1 true ATE119042T1 (de) 1995-03-15

Family

ID=21945570

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88905073T ATE119042T1 (de) 1987-05-05 1988-05-04 Verwendung eines viralen glykoprotein-impstoffes für intranasale immunisierung gegen eine virusinfektion.

Country Status (13)

Country Link
US (2) US5427782A (de)
EP (1) EP0363414B1 (de)
KR (1) KR890701127A (de)
CN (1) CN1031328A (de)
AT (1) ATE119042T1 (de)
AU (1) AU623857B2 (de)
CA (1) CA1337114C (de)
DE (1) DE3853210T2 (de)
IE (1) IE881314A1 (de)
IL (1) IL86268A0 (de)
NZ (1) NZ224422A (de)
WO (1) WO1988008718A1 (de)
ZA (1) ZA883172B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ224422A (en) * 1987-05-05 1990-11-27 Molecular Eng Ass Composition adapted for intranasal immunisation against viral infection comprising a glycoprotein complexed with a lipid
GB9018690D0 (en) * 1990-08-24 1990-10-10 Wellcome Found Vaccines
DE4407489A1 (de) * 1994-03-07 1995-09-14 Bayer Ag Vakzine zur Prävention von Respirations- und Reproduktionserkrankungen des Schweines
US20030054505A1 (en) * 1997-09-26 2003-03-20 Hong Jin Recombinant rsv expression systems and vaccines
US7465574B2 (en) * 1994-09-30 2008-12-16 Medimmune, Llc Recombinant RSV virus expression systems and vaccines
BR9610590A (pt) * 1995-09-22 2000-10-24 Connaught Lab Glicoproteìnas e vacinas de vìrus parainfluenza
US6830748B1 (en) * 1997-09-26 2004-12-14 Medimmune Vaccines, Inc. Recombinant RSV virus expression systems and vaccines
US6398774B1 (en) 1999-09-29 2002-06-04 Heska Corporation Intranasal delivery system
US7678087B2 (en) * 1999-09-29 2010-03-16 Heska Corporation Equine intranasal delivery system
SE0004532D0 (sv) * 2000-12-07 2000-12-07 Caldwell Karin Dahlgren Use of mucin
US6803041B2 (en) * 2001-03-20 2004-10-12 Boehringer Ingelheim Vetmedica, Inc. Equine herpesvirus vaccine
WO2003057824A2 (en) * 2001-11-13 2003-07-17 The Henry M. Jackson Foundation Compositions and methods for the inhibition of membrane fusion by paramyxoviruses
US9045727B2 (en) * 2002-05-17 2015-06-02 Emory University Virus-like particles, methods of preparation, and immunogenic compositions
US20060088909A1 (en) * 2002-05-17 2006-04-27 Compans Richard W Virus-like particles, methods of preparation, and immunogenic compositions
US7491395B2 (en) 2002-11-20 2009-02-17 Bestewil Holding B.V. Compositions comprising antigen-complexes, method of making same as well as methods of using the antigen-complexes for vaccination
AU2003296592A1 (en) 2002-11-20 2004-06-15 Crucell Holland B.V. Antigen-complexes
WO2004064740A2 (en) * 2003-01-16 2004-08-05 University Of Virginia Patent Foundation Sperm specific lysozyme-like proteins
EP1447080A1 (de) 2003-02-13 2004-08-18 Bestewil Holding B.V. Methode zur Herstellung von Virosomen-artigen Partikeln
TWI329130B (en) 2003-06-19 2010-08-21 Bestewil Holding Bv Functionally reconstituted viral membranes containing adjuvant
US8535683B2 (en) 2006-03-22 2013-09-17 Abbott Biologicals B.V. Intranasal or inhalational administration of virosomes
EP2058002A1 (de) 2007-10-31 2009-05-13 Bestewil Holding B.V. Rekonstituierte Virushüllen des Respiratory Syncytial Virus und Anwendung als Impfstoff für Respiratory Syncytial Virus
ES2532808T3 (es) * 2008-09-16 2015-03-31 Genomidea Inc. Agente terapéutico/profiláctico para cáncer de próstata
TWI510247B (zh) 2009-03-27 2015-12-01 中央研究院 預防病毒的免疫方法及組合物
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
CN114010776A (zh) 2010-06-09 2022-02-08 疫苗技术股份有限公司 用于增强抗逆转录病毒治疗的hiv感染者的治疗性免疫
TWI537385B (zh) 2010-11-04 2016-06-11 中央研究院 產生具簡單醣基化之表面蛋白質之病毒顆粒的方法
AU2012253359B2 (en) 2011-05-11 2017-06-08 Children's Medical Center Corporation Multiple antigen presenting immunogenic composition, and methods and uses thereof
CA2900008C (en) 2013-02-07 2025-10-07 Children's Medical Center Corporation PROTEIN ANTIGENS THAT CONFER PROTECTION AGAINST COLONIZATION AND/OR PNEUMOCOCCAL DISEASE
MA47016A (fr) 2015-10-22 2018-08-29 Modernatx Inc Vaccins contre les virus respiratoires
MA50335A (fr) 2016-12-08 2020-08-19 Modernatx Inc Vaccins à acide nucléique contre des virus respiratoires
EP3595676A4 (de) 2017-03-17 2021-05-05 Modernatx, Inc. Rna-impfstoffe gegen zoonosen
US11351242B1 (en) 2019-02-12 2022-06-07 Modernatx, Inc. HMPV/hPIV3 mRNA vaccine composition
CN111375055B (zh) * 2020-02-20 2021-09-03 陈宛莎 一种2019-nCoV亚单位疫苗组合物及其免疫方法
CN115327132A (zh) * 2022-08-09 2022-11-11 中国医学科学院北京协和医院 一种用于评估下肢缺血患者病情严重度的生物标志物及其用途

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3544680A (en) * 1968-10-09 1970-12-01 Wistar Inst Intranasal immunization against rubella
US3634587A (en) * 1969-11-06 1972-01-11 Ralston Purina Co Method of immunizing cattle against bovine respiratory disease syndrome
US3950512A (en) * 1972-07-25 1976-04-13 Pitman-Moore, Inc. Animal vaccines
US3927208A (en) * 1973-05-14 1975-12-16 Rit Rech Ind Therapeut Live bovine adenovirus vaccines, preparation thereof and method of vaccination using them
US3962421A (en) * 1973-06-18 1976-06-08 American Home Products Corporation Method for the disruption of lipid-containing viruses
US3953592A (en) * 1973-09-27 1976-04-27 Recherche Et Industrie Therapeutiques (R.I.T.) Live influenza virus vaccines and preparation thereof
US4132775A (en) * 1973-12-03 1979-01-02 Richardson-Merrell Inc. Infectious bovine rhinotracheitis virus vaccine and method of preparing and using the same
US3962424A (en) * 1974-01-31 1976-06-08 Recherche Et Industrie Therapeutiques (R.I.T.) Live brovine adenovirus vaccines, preparation thereof and method of vaccination using them
US3962423A (en) * 1974-02-04 1976-06-08 Recherche Et Industrie Therapeutiques (R.I.T.) Live influenza type B virus vaccines and preparation thereof
US3962422A (en) * 1975-02-18 1976-06-08 Syntex (U.S.A.) Inc. Method for immunizing nursing piglets against transmissible gastroenteritis(TGE) virus
US4110433A (en) * 1976-04-23 1978-08-29 Philips Roxane, Inc. Equine rhinopneumonitis virus
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
GB2026340B (en) * 1978-07-03 1982-12-22 Ash P Stabilising microvesicles
US4318903A (en) * 1978-07-12 1982-03-09 Smithkline-Rit Live influenza virus vaccine and the preparation thereof
US4337314A (en) * 1979-05-23 1982-06-29 Research Corporation Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype
US4235877A (en) * 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4261975A (en) * 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US4303644A (en) * 1979-10-16 1981-12-01 Norden Laboratories, Inc. Feline infectious peritonitis virus vaccines
FR2475572A1 (fr) * 1980-02-11 1981-08-14 Pasteur Institut Procede pour l'obtention de fragments de virus a enveloppe lipidique, en particulier d'antigenes utilisables comme vaccins, produits obtenus et applications
DE3014189A1 (de) 1980-04-14 1981-10-15 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur herstellung eines immunogenen membranproteinaggregats von influenza-, parainfluenza- und rhabdo-viren
FR2483779A1 (fr) 1980-06-05 1981-12-11 Synthelabo Procede pour isoler des antigenes glycoproteiques viraux et son application a la preparation de vaccins
US4512972A (en) * 1980-06-30 1985-04-23 Kureha Chemical Industry Co., Ltd. Nasal preparation and processes for their production
US4552758A (en) * 1983-12-20 1985-11-12 St. Jude Children's Research Hospital Human use of avian-human reassortants as vaccines for influenza A virus
US4663161A (en) * 1985-04-22 1987-05-05 Mannino Raphael J Liposome methods and compositions
US4790987A (en) * 1985-11-15 1988-12-13 Research Corporation Viral glycoprotein subunit vaccine
NZ224422A (en) * 1987-05-05 1990-11-27 Molecular Eng Ass Composition adapted for intranasal immunisation against viral infection comprising a glycoprotein complexed with a lipid
NZ224567A (en) * 1987-05-19 1990-08-28 Yissum Res Dev Co Vaccine against newcastle disease virus comprising a live immunogenic lentogenic or mesogenic strain of newcastle disease virus in combination with a liquid containing a mineral or vegetable oil
EP0306912A3 (de) * 1987-09-08 1989-07-05 Albany Medical College Zur selektiven Anregung der Antikörperbildung befähigte immunogene Produkte und ihre Verwendung in pharmazeutischen Zusammensetzungen.
US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines

Also Published As

Publication number Publication date
DE3853210D1 (de) 1995-04-06
IE881314A1 (en) 2001-11-28
DE3853210T2 (de) 1995-10-12
CN1031328A (zh) 1989-03-01
AU623857B2 (en) 1992-05-28
EP0363414B1 (de) 1995-03-01
US5843451A (en) 1998-12-01
IL86268A0 (en) 1988-11-15
KR890701127A (ko) 1989-12-19
WO1988008718A1 (en) 1988-11-17
NZ224422A (en) 1990-11-27
US5427782A (en) 1995-06-27
EP0363414A1 (de) 1990-04-18
ZA883172B (en) 1989-03-29
CA1337114C (en) 1995-09-26
EP0363414A4 (de) 1990-03-21
AU1808188A (en) 1988-12-06
IE881314L (en) 1988-11-05

Similar Documents

Publication Publication Date Title
ATE119042T1 (de) Verwendung eines viralen glykoprotein-impstoffes für intranasale immunisierung gegen eine virusinfektion.
DK0584348T3 (da) Genetisk vaccine mod immundefektvirusser
DK0610250T4 (da) Vaccine med porcint reproduktivt respiratorisk syndrom (PRRS) og diagnose heraf
NO975434L (no) Fremgangsmåte for fremstilling av influensa hemagglutinin multivalente vaksiner
ES2009350A6 (es) Procedimiento para la preparacion de vectores de expresion que codifican una nueva proteina.
ATE213166T1 (de) Prrs-(porcine reproductive and respiratory syndrome)-virusvakzin
DE3786824D1 (de) Rekombinante herpes simplex-viren, vakzine und verfahren.
ES2042751T3 (es) Nuevo procedimiento para la purificacion de viriones de la hepatitis a.
FI102616B1 (fi) Menetelmä rokotteen valmistamiseksi ihmisen parainfluenssa-viruksen tyyppiä 3 varten ja menetelmässä käytettävä ilmentämisjärjestelmä
DE69420970D1 (de) Impfstoff zubereitungen
DK0762895T3 (da) Syntetisk vaccine til beskyttelse mod infektion med human immundefektvirus
NO175846C (no) Fremgangsmåte for å oppnå et immunogen
DK8789D0 (da) Fremgangsmaade til fremstilling af modificerede, staerkt afsvaekkede rna-virusstammer samt vaccine og dens anvendelse
ES449941A1 (es) Un metodo de preparacion de un nuevo virus vivo de la rabia.
DE69015314D1 (de) Verwendung von adenylzyclase als vakzin gegen bordetella.
ES466758A1 (es) Un procedimiento de preparacion de un virus sincitial respi-ratorio atenuado.
DK0485463T3 (da) Svækket hundeparvovirus (CPV), vaccine omfattende CPV og fremgangsmåde til forebyggelse af CPV-infektion i hunde
ATE84722T1 (de) Tollwut-lebendimpfstoff.
AP1561A (en) Use of non-cytolytic retrovirus as vaccines for the treatment of HIV infection.
ES471766A1 (es) Un procedimiento de preparacion de un virus vivo atenuado dela para-influenza
DK0542895T3 (da) Krydsreaktiv influenza A immunisering
RU97115149A (ru) Способ вакцинации против вирусного гепатита в
NL7506620A (en) Cell-free chickenpox virus prodn - for vaccines, by passing on human or monkey cells until attenuated then recovering the virus in presence of a stabiliser
ES8801959A1 (es) Un procedimiento para ensayos de sangre humana respecto de la presencia de anticuerpos frente al agente etiologico viral de sida
TH45965A3 (th) วิธีการสำหรับการเหนี่ยวนำภูมิคุ้มกันต่อไวรัส

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee
RZN Patent revoked