DE3853210T2 - Verwendung eines viralen glykoprotein-impstoffes für intranasale immunisierung gegen eine virusinfektion. - Google Patents
Verwendung eines viralen glykoprotein-impstoffes für intranasale immunisierung gegen eine virusinfektion.Info
- Publication number
- DE3853210T2 DE3853210T2 DE3853210T DE3853210T DE3853210T2 DE 3853210 T2 DE3853210 T2 DE 3853210T2 DE 3853210 T DE3853210 T DE 3853210T DE 3853210 T DE3853210 T DE 3853210T DE 3853210 T2 DE3853210 T2 DE 3853210T2
- Authority
- DE
- Germany
- Prior art keywords
- virus infection
- immunization against
- viral glycoprotein
- intranasal immunization
- glycoprotein vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4682087A | 1987-05-05 | 1987-05-05 | |
PCT/US1988/001502 WO1988008718A1 (en) | 1987-05-05 | 1988-05-04 | Intranasal immunization against viral infection using viral glycoprotein subunit vaccine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3853210D1 DE3853210D1 (de) | 1995-04-06 |
DE3853210T2 true DE3853210T2 (de) | 1995-10-12 |
Family
ID=21945570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3853210T Revoked DE3853210T2 (de) | 1987-05-05 | 1988-05-04 | Verwendung eines viralen glykoprotein-impstoffes für intranasale immunisierung gegen eine virusinfektion. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5427782A (de) |
EP (1) | EP0363414B1 (de) |
KR (1) | KR890701127A (de) |
CN (1) | CN1031328A (de) |
AT (1) | ATE119042T1 (de) |
AU (1) | AU623857B2 (de) |
CA (1) | CA1337114C (de) |
DE (1) | DE3853210T2 (de) |
IE (1) | IE881314A1 (de) |
IL (1) | IL86268A0 (de) |
NZ (1) | NZ224422A (de) |
WO (1) | WO1988008718A1 (de) |
ZA (1) | ZA883172B (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ224422A (en) * | 1987-05-05 | 1990-11-27 | Molecular Eng Ass | Composition adapted for intranasal immunisation against viral infection comprising a glycoprotein complexed with a lipid |
GB9018690D0 (en) * | 1990-08-24 | 1990-10-10 | Wellcome Found | Vaccines |
DE4407489A1 (de) * | 1994-03-07 | 1995-09-14 | Bayer Ag | Vakzine zur Prävention von Respirations- und Reproduktionserkrankungen des Schweines |
US20030054505A1 (en) * | 1997-09-26 | 2003-03-20 | Hong Jin | Recombinant rsv expression systems and vaccines |
US7465574B2 (en) * | 1994-09-30 | 2008-12-16 | Medimmune, Llc | Recombinant RSV virus expression systems and vaccines |
WO1997011093A2 (en) * | 1995-09-22 | 1997-03-27 | Connaught Laboratories Limited | Parainfluenza virus glycoproteins and vaccines |
US6830748B1 (en) * | 1997-09-26 | 2004-12-14 | Medimmune Vaccines, Inc. | Recombinant RSV virus expression systems and vaccines |
US7678087B2 (en) * | 1999-09-29 | 2010-03-16 | Heska Corporation | Equine intranasal delivery system |
US6398774B1 (en) | 1999-09-29 | 2002-06-04 | Heska Corporation | Intranasal delivery system |
SE0004532D0 (sv) * | 2000-12-07 | 2000-12-07 | Caldwell Karin Dahlgren | Use of mucin |
US6803041B2 (en) | 2001-03-20 | 2004-10-12 | Boehringer Ingelheim Vetmedica, Inc. | Equine herpesvirus vaccine |
WO2003057824A2 (en) * | 2001-11-13 | 2003-07-17 | The Henry M. Jackson Foundation | Compositions and methods for the inhibition of membrane fusion by paramyxoviruses |
WO2004042001A2 (en) * | 2002-05-17 | 2004-05-21 | Emory University | Virus-like particles, methods of preparation, and immonogenic compositions |
US9045727B2 (en) * | 2002-05-17 | 2015-06-02 | Emory University | Virus-like particles, methods of preparation, and immunogenic compositions |
US7491395B2 (en) | 2002-11-20 | 2009-02-17 | Bestewil Holding B.V. | Compositions comprising antigen-complexes, method of making same as well as methods of using the antigen-complexes for vaccination |
DE60335742D1 (de) | 2002-11-20 | 2011-02-24 | Bestewil Holding Bv | Zusammensetzungen mit antigen-komplexen,verfahren zu ihrer herstellung und verfahren zur verwendung derantigen-komplexe zur vakzinierung |
US20060089297A1 (en) * | 2003-01-16 | 2006-04-27 | Herr John C | Sperm specific lysozyme-like proteins |
EP1447080A1 (de) | 2003-02-13 | 2004-08-18 | Bestewil Holding B.V. | Methode zur Herstellung von Virosomen-artigen Partikeln |
AR056245A1 (es) | 2003-06-19 | 2007-10-03 | Bestewil Holding Bv | Membranas virales reconstituidas funcionales que contienen un coadyuvante |
US8535683B2 (en) | 2006-03-22 | 2013-09-17 | Abbott Biologicals B.V. | Intranasal or inhalational administration of virosomes |
EP2058002A1 (de) | 2007-10-31 | 2009-05-13 | Bestewil Holding B.V. | Rekonstituierte Virushüllen des Respiratory Syncytial Virus und Anwendung als Impfstoff für Respiratory Syncytial Virus |
EP2345415B1 (de) * | 2008-09-16 | 2015-01-21 | GenomIdea Inc. | Therapeutisches/prophylaktisches mittel gegen prostatakrebs |
CN103200961B (zh) | 2009-03-27 | 2017-10-27 | 中央研究院 | 抗病毒免疫的方法和组合物 |
WO2010144797A2 (en) | 2009-06-12 | 2010-12-16 | Vaccine Technologies, Incorporated | Influenza vaccines with enhanced immunogenicity and uses thereof |
EP2579892A2 (de) | 2010-06-09 | 2013-04-17 | Vaccine Technologies, Incorporated | Therapeutische immunisierung von hiv-infizierten personen mit stabiler antiretroviraler behandlung |
TWI537385B (zh) | 2010-11-04 | 2016-06-11 | 中央研究院 | 產生具簡單醣基化之表面蛋白質之病毒顆粒的方法 |
BR112013028887B1 (pt) | 2011-05-11 | 2020-10-06 | Children's Medical Center Corporation | Composição imunogênica apresentando múltiplos antígenos, e métodos e usos dos mesmos |
CA2900008A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
MD3718565T2 (ro) | 2015-10-22 | 2022-09-30 | Modernatx Inc | Vaccinuri împotriva virusului respirator |
US11103578B2 (en) | 2016-12-08 | 2021-08-31 | Modernatx, Inc. | Respiratory virus nucleic acid vaccines |
WO2018170347A1 (en) | 2017-03-17 | 2018-09-20 | Modernatx, Inc. | Zoonotic disease rna vaccines |
US11351242B1 (en) | 2019-02-12 | 2022-06-07 | Modernatx, Inc. | HMPV/hPIV3 mRNA vaccine composition |
CN111375055B (zh) * | 2020-02-20 | 2021-09-03 | 陈宛莎 | 一种2019-nCoV亚单位疫苗组合物及其免疫方法 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3544680A (en) * | 1968-10-09 | 1970-12-01 | Wistar Inst | Intranasal immunization against rubella |
US3634587A (en) * | 1969-11-06 | 1972-01-11 | Ralston Purina Co | Method of immunizing cattle against bovine respiratory disease syndrome |
US3950512A (en) * | 1972-07-25 | 1976-04-13 | Pitman-Moore, Inc. | Animal vaccines |
US3927208A (en) * | 1973-05-14 | 1975-12-16 | Rit Rech Ind Therapeut | Live bovine adenovirus vaccines, preparation thereof and method of vaccination using them |
US3962421A (en) * | 1973-06-18 | 1976-06-08 | American Home Products Corporation | Method for the disruption of lipid-containing viruses |
US3953592A (en) * | 1973-09-27 | 1976-04-27 | Recherche Et Industrie Therapeutiques (R.I.T.) | Live influenza virus vaccines and preparation thereof |
US4132775A (en) * | 1973-12-03 | 1979-01-02 | Richardson-Merrell Inc. | Infectious bovine rhinotracheitis virus vaccine and method of preparing and using the same |
US3962424A (en) * | 1974-01-31 | 1976-06-08 | Recherche Et Industrie Therapeutiques (R.I.T.) | Live brovine adenovirus vaccines, preparation thereof and method of vaccination using them |
US3962423A (en) * | 1974-02-04 | 1976-06-08 | Recherche Et Industrie Therapeutiques (R.I.T.) | Live influenza type B virus vaccines and preparation thereof |
US3962422A (en) * | 1975-02-18 | 1976-06-08 | Syntex (U.S.A.) Inc. | Method for immunizing nursing piglets against transmissible gastroenteritis(TGE) virus |
US4110433A (en) * | 1976-04-23 | 1978-08-29 | Philips Roxane, Inc. | Equine rhinopneumonitis virus |
US4196265A (en) * | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4172124A (en) * | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
GB2026340B (en) * | 1978-07-03 | 1982-12-22 | Ash P | Stabilising microvesicles |
US4318903A (en) * | 1978-07-12 | 1982-03-09 | Smithkline-Rit | Live influenza virus vaccine and the preparation thereof |
US4337314A (en) * | 1979-05-23 | 1982-06-29 | Research Corporation | Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype |
US4235877A (en) * | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
US4261975A (en) * | 1979-09-19 | 1981-04-14 | Merck & Co., Inc. | Viral liposome particle |
US4303644A (en) * | 1979-10-16 | 1981-12-01 | Norden Laboratories, Inc. | Feline infectious peritonitis virus vaccines |
FR2475572A1 (fr) * | 1980-02-11 | 1981-08-14 | Pasteur Institut | Procede pour l'obtention de fragments de virus a enveloppe lipidique, en particulier d'antigenes utilisables comme vaccins, produits obtenus et applications |
DE3014189A1 (de) | 1980-04-14 | 1981-10-15 | Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg | Verfahren zur herstellung eines immunogenen membranproteinaggregats von influenza-, parainfluenza- und rhabdo-viren |
FR2483779A1 (fr) | 1980-06-05 | 1981-12-11 | Synthelabo | Procede pour isoler des antigenes glycoproteiques viraux et son application a la preparation de vaccins |
US4512972A (en) * | 1980-06-30 | 1985-04-23 | Kureha Chemical Industry Co., Ltd. | Nasal preparation and processes for their production |
US4552758A (en) * | 1983-12-20 | 1985-11-12 | St. Jude Children's Research Hospital | Human use of avian-human reassortants as vaccines for influenza A virus |
US4663161A (en) * | 1985-04-22 | 1987-05-05 | Mannino Raphael J | Liposome methods and compositions |
US4790987A (en) * | 1985-11-15 | 1988-12-13 | Research Corporation | Viral glycoprotein subunit vaccine |
NZ224422A (en) * | 1987-05-05 | 1990-11-27 | Molecular Eng Ass | Composition adapted for intranasal immunisation against viral infection comprising a glycoprotein complexed with a lipid |
NZ224567A (en) * | 1987-05-19 | 1990-08-28 | Yissum Res Dev Co | Vaccine against newcastle disease virus comprising a live immunogenic lentogenic or mesogenic strain of newcastle disease virus in combination with a liquid containing a mineral or vegetable oil |
EP0306912A3 (de) * | 1987-09-08 | 1989-07-05 | Albany Medical College | Zur selektiven Anregung der Antikörperbildung befähigte immunogene Produkte und ihre Verwendung in pharmazeutischen Zusammensetzungen. |
US5223254A (en) * | 1987-09-29 | 1993-06-29 | Praxis Biologics, Inc. | Respiratory syncytial virus: vaccines |
-
1988
- 1988-04-28 NZ NZ224422A patent/NZ224422A/en unknown
- 1988-05-02 IE IE19881314A patent/IE881314A1/en not_active IP Right Cessation
- 1988-05-03 CA CA000565787A patent/CA1337114C/en not_active Expired - Fee Related
- 1988-05-03 IL IL86268A patent/IL86268A0/xx unknown
- 1988-05-04 EP EP88905073A patent/EP0363414B1/de not_active Revoked
- 1988-05-04 DE DE3853210T patent/DE3853210T2/de not_active Revoked
- 1988-05-04 AT AT88905073T patent/ATE119042T1/de not_active IP Right Cessation
- 1988-05-04 ZA ZA883172A patent/ZA883172B/xx unknown
- 1988-05-04 AU AU18081/88A patent/AU623857B2/en not_active Ceased
- 1988-05-04 WO PCT/US1988/001502 patent/WO1988008718A1/en not_active Application Discontinuation
- 1988-05-05 CN CN88102673A patent/CN1031328A/zh active Pending
-
1989
- 1989-01-05 KR KR1019890700002A patent/KR890701127A/ko not_active Application Discontinuation
-
1992
- 1992-05-20 US US07/887,130 patent/US5427782A/en not_active Expired - Fee Related
-
1996
- 1996-10-11 US US08/728,735 patent/US5843451A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0363414A1 (de) | 1990-04-18 |
ATE119042T1 (de) | 1995-03-15 |
EP0363414A4 (de) | 1990-03-21 |
WO1988008718A1 (en) | 1988-11-17 |
DE3853210D1 (de) | 1995-04-06 |
NZ224422A (en) | 1990-11-27 |
KR890701127A (ko) | 1989-12-19 |
EP0363414B1 (de) | 1995-03-01 |
CN1031328A (zh) | 1989-03-01 |
IE881314L (en) | 1988-11-05 |
AU1808188A (en) | 1988-12-06 |
US5427782A (en) | 1995-06-27 |
CA1337114C (en) | 1995-09-26 |
IL86268A0 (en) | 1988-11-15 |
US5843451A (en) | 1998-12-01 |
AU623857B2 (en) | 1992-05-28 |
IE881314A1 (en) | 2001-11-28 |
ZA883172B (en) | 1989-03-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8339 | Ceased/non-payment of the annual fee | ||
8331 | Complete revocation |