ATE110376T1 - Biphenyl-derivate, verfahren zu deren herstellung und deren zwischenprodukte. - Google Patents

Biphenyl-derivate, verfahren zu deren herstellung und deren zwischenprodukte.

Info

Publication number
ATE110376T1
ATE110376T1 AT90401483T AT90401483T ATE110376T1 AT E110376 T1 ATE110376 T1 AT E110376T1 AT 90401483 T AT90401483 T AT 90401483T AT 90401483 T AT90401483 T AT 90401483T AT E110376 T1 ATE110376 T1 AT E110376T1
Authority
AT
Austria
Prior art keywords
group
biphenyl derivatives
chem
substituted
formula
Prior art date
Application number
AT90401483T
Other languages
English (en)
Inventor
Tameo Iwasaki
Kazuhiko Kondo
Yuzo Matsuoka
Mamoru Matsumoto
Masaki Sugiura
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Application granted granted Critical
Publication of ATE110376T1 publication Critical patent/ATE110376T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT90401483T 1989-06-02 1990-06-01 Biphenyl-derivate, verfahren zu deren herstellung und deren zwischenprodukte. ATE110376T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1141988A JPH0660142B2 (ja) 1989-06-02 1989-06-02 ビフェニル誘導体、その製法及びその合成中間体

Publications (1)

Publication Number Publication Date
ATE110376T1 true ATE110376T1 (de) 1994-09-15

Family

ID=15304785

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90401483T ATE110376T1 (de) 1989-06-02 1990-06-01 Biphenyl-derivate, verfahren zu deren herstellung und deren zwischenprodukte.

Country Status (10)

Country Link
US (1) US5103023A (de)
EP (1) EP0401125B1 (de)
JP (1) JPH0660142B2 (de)
KR (1) KR0130757B1 (de)
AT (1) ATE110376T1 (de)
CA (1) CA2017897A1 (de)
DE (1) DE69011748T2 (de)
DK (1) DK0401125T3 (de)
ES (1) ES2063305T3 (de)
HK (1) HK174395A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344958A (en) * 1992-11-23 1994-09-06 Rohm And Haas Company Insecticidal N'-substituted-N,N'-diacylhydrazines
US5530028A (en) * 1992-11-23 1996-06-25 Rohm And Haas Company Insecticidal N'-substituted-N,N'-diacylhydrazines
US5612341A (en) * 1995-06-07 1997-03-18 Biotech Research Laboratories Brominated hexahydroxybiphenyl derivatives
CN102250085B (zh) * 2010-05-21 2014-01-22 四川大学 联苯双酯衍生物及其在制备自身免疫性疾病药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60209582A (ja) * 1984-04-04 1985-10-22 Isukura Sangyo Kk Ｄｄｂの合成方法
DE3789352T2 (de) * 1986-05-27 1994-06-23 Tsumura & Co Neue biphenylabkömmlinge, deren herstellung und verwendung.
EP0269754B1 (de) * 1986-06-13 1993-11-03 TSUMURA & CO. Biphenylabkömmlinge, verfahren zur herstellung und verwendung
JPS63192771A (ja) * 1987-02-06 1988-08-10 Isukura Sangyo Kk ２，３，２′，３′−ビス（メチレンジオキシ）ビフエニル化合物、その製造法およびそれを含む肝疾患治療剤

Also Published As

Publication number Publication date
EP0401125B1 (de) 1994-08-24
KR910000623A (ko) 1991-01-29
CA2017897A1 (en) 1990-12-02
US5103023A (en) 1992-04-07
DK0401125T3 (da) 1994-09-19
DE69011748D1 (de) 1994-09-29
JPH0660142B2 (ja) 1994-08-10
DE69011748T2 (de) 1995-01-12
EP0401125A2 (de) 1990-12-05
KR0130757B1 (ko) 1998-04-07
ES2063305T3 (es) 1995-01-01
HK174395A (en) 1995-11-24
EP0401125A3 (de) 1991-04-24
JPH037246A (ja) 1991-01-14

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