ATE108279T1 - Verfahren zum schnellen mischen kleiner volumina zur verbesserung biologischer reaktionen. - Google Patents

Verfahren zum schnellen mischen kleiner volumina zur verbesserung biologischer reaktionen.

Info

Publication number
ATE108279T1
ATE108279T1 AT88903636T AT88903636T ATE108279T1 AT E108279 T1 ATE108279 T1 AT E108279T1 AT 88903636 T AT88903636 T AT 88903636T AT 88903636 T AT88903636 T AT 88903636T AT E108279 T1 ATE108279 T1 AT E108279T1
Authority
AT
Austria
Prior art keywords
microspheres
small volume
biological response
cells
volume mixing
Prior art date
Application number
AT88903636T
Other languages
English (en)
Inventor
Wallace H Coulter
John David Hollinger
Thomas Russell
Carlos Rodriguez
Ronald Paul
Kenneth H Kortright
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Corp filed Critical Coulter Corp
Application granted granted Critical
Publication of ATE108279T1 publication Critical patent/ATE108279T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/201Holders therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/22Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
AT88903636T 1987-03-13 1988-03-11 Verfahren zum schnellen mischen kleiner volumina zur verbesserung biologischer reaktionen. ATE108279T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2533787A 1987-03-13 1987-03-13

Publications (1)

Publication Number Publication Date
ATE108279T1 true ATE108279T1 (de) 1994-07-15

Family

ID=21825432

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88903636T ATE108279T1 (de) 1987-03-13 1988-03-11 Verfahren zum schnellen mischen kleiner volumina zur verbesserung biologischer reaktionen.

Country Status (10)

Country Link
EP (1) EP0349591B1 (de)
KR (1) KR890700397A (de)
CN (1) CN1018673B (de)
AT (1) ATE108279T1 (de)
AU (1) AU610581B2 (de)
CA (1) CA1326435C (de)
DE (1) DE3850573T2 (de)
ES (1) ES2011653A6 (de)
NO (1) NO177809C (de)
WO (1) WO1988006918A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2644894B1 (fr) * 1989-03-24 1994-05-13 Sanofi Trousse et methode de dosage enzymatique applicables a des cellules entieres
FR2644893B1 (fr) * 1989-03-24 1991-07-12 Sanofi Sa Trousse et methode de dosage applicables a des cellules entieres
US5340719A (en) * 1990-11-23 1994-08-23 Corporation Coulter Method and apparatus for optically screening microscopic cells
US5348859A (en) * 1990-11-23 1994-09-20 Coulter Corporation Method and apparatus for obtaining an absolute white blood cell subset count and white blood cell multipart differential
WO1992009878A1 (en) * 1990-11-23 1992-06-11 Coulter Corporation Method and apparatus for optically screening microscopic cells
CN101149371B (zh) * 2007-10-26 2011-03-09 南方医科大学珠江医院 一种鼠免疫状态监测试剂及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985649A (en) * 1974-11-25 1976-10-12 Eddelman Roy T Ferromagnetic separation process and material
US3970518A (en) * 1975-07-01 1976-07-20 General Electric Company Magnetic separation of biological particles
US4267234A (en) * 1978-03-17 1981-05-12 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US4230685A (en) * 1979-02-28 1980-10-28 Northwestern University Method of magnetic separation of cells and the like, and microspheres for use therein
US4325910A (en) * 1979-07-11 1982-04-20 Technicraft, Inc. Automated multiple-purpose chemical-analysis apparatus
US4276260A (en) * 1980-01-28 1981-06-30 Coulter Electronics, Inc. Fluid transfer mechanism
EP0051496B1 (de) * 1980-11-04 1986-02-05 Olympus Optical Co., Ltd. Verfahren und Vorrichtung zur Analyse immunologischer Agglutinationsreaktionen
WO1982003462A1 (en) * 1981-03-27 1982-10-14 Ltd Biospecia Immunological analysis and a biochemical agent therefore
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
US4550017A (en) * 1982-10-15 1985-10-29 Syntex (U.S.A.) Inc. Fluorescence screening for blood typing
US4485175A (en) * 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes
US4584277A (en) * 1983-04-05 1986-04-22 Syntex (U.S.A.) Inc. Fluorescent multiparameter particle analysis
US4672040A (en) * 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US4628026A (en) * 1983-11-15 1986-12-09 Dietlind Gardell Method and apparatus for automated double fluorochromization analysis in lymphocytotoxicity testing
JPS61225656A (ja) * 1985-03-29 1986-10-07 Toshiba Corp 検体検査装置

Also Published As

Publication number Publication date
EP0349591A1 (de) 1990-01-10
CA1326435C (en) 1994-01-25
AU1570088A (en) 1988-10-10
EP0349591B1 (de) 1994-07-06
WO1988006918A1 (en) 1988-09-22
AU610581B2 (en) 1991-05-23
DE3850573D1 (de) 1994-08-11
DE3850573T2 (de) 1994-10-27
NO885042D0 (no) 1988-11-11
CN88101256A (zh) 1988-09-21
NO885042L (no) 1989-01-09
NO177809C (no) 1995-11-22
EP0349591A4 (en) 1991-01-16
KR890700397A (ko) 1989-04-24
CN1018673B (zh) 1992-10-14
NO177809B (no) 1995-08-14
ES2011653A6 (es) 1990-02-01

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