ATE104987T1 - Verfahren zur anreicherung der blutgerinnungsfaktoren ii, vii, ix und x. - Google Patents
Verfahren zur anreicherung der blutgerinnungsfaktoren ii, vii, ix und x.Info
- Publication number
- ATE104987T1 ATE104987T1 AT8989112443T AT89112443T ATE104987T1 AT E104987 T1 ATE104987 T1 AT E104987T1 AT 8989112443 T AT8989112443 T AT 8989112443T AT 89112443 T AT89112443 T AT 89112443T AT E104987 T1 ATE104987 T1 AT E104987T1
- Authority
- AT
- Austria
- Prior art keywords
- factors
- vii
- coagaging
- encouragement
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 108010039209 Blood Coagulation Factors Proteins 0.000 abstract 3
- 102000015081 Blood Coagulation Factors Human genes 0.000 abstract 3
- 239000003114 blood coagulation factor Substances 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 2
- 102100022641 Coagulation factor IX Human genes 0.000 abstract 1
- 108010076282 Factor IX Proteins 0.000 abstract 1
- 229940019700 blood coagulation factors Drugs 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 229960004222 factor ix Drugs 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3826792A DE3826792C1 (enExample) | 1988-08-06 | 1988-08-06 | |
| EP89112443A EP0354354B1 (de) | 1988-08-06 | 1989-07-07 | Verfahren zur Anreicherung der Blutgerinnungsfaktoren II, VII, IX und X |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE104987T1 true ATE104987T1 (de) | 1994-05-15 |
Family
ID=6360383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT8989112443T ATE104987T1 (de) | 1988-08-06 | 1989-07-07 | Verfahren zur anreicherung der blutgerinnungsfaktoren ii, vii, ix und x. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5071961A (enExample) |
| EP (1) | EP0354354B1 (enExample) |
| JP (1) | JP2579217B2 (enExample) |
| AT (1) | ATE104987T1 (enExample) |
| DE (2) | DE3826792C1 (enExample) |
| ES (1) | ES2055761T3 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3914869C1 (enExample) * | 1989-05-05 | 1990-08-09 | Biotest Pharma Gmbh, 6072 Dreieich, De | |
| DE69033033T2 (de) * | 1989-07-20 | 1999-10-28 | Analytical Control Systems, Inc. | Verbesserte kontrollverfahren für stabile blutkoagulation |
| DK0573605T3 (da) * | 1991-03-01 | 2001-01-02 | Rhone Poulenc Rorer Int | Fremstilling af faktor IX |
| US5589571A (en) * | 1994-10-28 | 1996-12-31 | Cor Therapeutics, Inc. | Process for production of inhibited forms of activated blood factors |
| DE19504852C2 (de) * | 1995-02-15 | 2003-01-23 | Octapharma Ag Lachen | Verfahren zur Reinigung Vitamin K-abhängiger Gerinnungsfaktoren durch Affinitäts-Chromatographie |
| US5714583A (en) | 1995-06-07 | 1998-02-03 | Genetics Institute, Inc. | Factor IX purification methods |
| JP3023657B2 (ja) * | 1995-09-25 | 2000-03-21 | 本田技研工業株式会社 | 自動2輪車のリヤスイングアーム |
| US5762757A (en) * | 1996-12-05 | 1998-06-09 | Betzdearborn Inc. | Methods for inhibiting organic contaminant deposition in pulp and papermaking systems |
| FR2948664B1 (fr) | 2009-07-31 | 2013-11-01 | Lfb Biotechnologies | Procede pour la purification de proteines de la coagulation a domaine gla |
| FR2948665B1 (fr) * | 2009-07-31 | 2011-09-23 | Lfb Biotechnologies | Procede pour la purification de proteines de la coagulation a domaine gla actives |
| JP2012050386A (ja) * | 2010-09-01 | 2012-03-15 | Kaneka Corp | 2種類以上の多孔質充填剤を充填するカラム |
| JP5836577B2 (ja) * | 2010-09-14 | 2015-12-24 | 株式会社カネカ | クリングル配列を有する蛋白質またはペプチドを精製または除去するアフィニティ担体の製造方法、その精製方法、除去方法 |
| SG191186A1 (en) | 2010-12-15 | 2013-07-31 | Baxter Int | Eluate collection using conductivity gradient |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE15489T1 (de) * | 1980-05-27 | 1985-09-15 | Miles Lab | Die blutkoagulation aktivierendes produkt und verfahren zu dessen herstellung. |
| DE3033932C2 (de) * | 1980-09-10 | 1984-05-24 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | Verfahren zur Kaltsterilisation von Blutgerinnungsfaktor VIII enthaltenden Präparaten |
| US4481189A (en) * | 1982-04-14 | 1984-11-06 | New York Blood Center Inc. | Process for preparing sterilized plasma and plasma derivatives |
| US4447416A (en) * | 1982-04-28 | 1984-05-08 | American National Red Cross | Plasma protein concentrates of reduced thrombogenicity and their use in clinical replacement therapy |
| US4508709A (en) * | 1983-12-05 | 1985-04-02 | Armour Pharmaceutical Company | Process for purifying factor VIII:C |
| US4721572A (en) * | 1985-07-12 | 1988-01-26 | Miles Laboratories, Inc. | Purfication of blood clotting factors and other blood proteins on non-carbohydrate sulfated matrices |
| NL8701915A (nl) * | 1987-08-14 | 1989-03-01 | Waander Riethorst | Adsorbensmateriaal en toepassing daarvan voor het isoleren van stollingsfaktoren. |
| US5118614A (en) * | 1988-01-18 | 1992-06-02 | Tessek Sdruzeni Praha | Concentrates of coagulation factors ii, vii, ix and x, method of their preparation and use |
-
1988
- 1988-08-06 DE DE3826792A patent/DE3826792C1/de not_active Expired
-
1989
- 1989-07-07 ES ES89112443T patent/ES2055761T3/es not_active Expired - Lifetime
- 1989-07-07 DE DE58907555T patent/DE58907555D1/de not_active Expired - Fee Related
- 1989-07-07 AT AT8989112443T patent/ATE104987T1/de not_active IP Right Cessation
- 1989-07-07 EP EP89112443A patent/EP0354354B1/de not_active Expired - Lifetime
- 1989-07-20 US US07/383,371 patent/US5071961A/en not_active Expired - Fee Related
- 1989-08-04 JP JP1201463A patent/JP2579217B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE58907555D1 (de) | 1994-06-01 |
| JPH02113893A (ja) | 1990-04-26 |
| DE3826792C1 (enExample) | 1989-07-06 |
| ES2055761T3 (es) | 1994-09-01 |
| JP2579217B2 (ja) | 1997-02-05 |
| EP0354354A2 (de) | 1990-02-14 |
| US5071961A (en) | 1991-12-10 |
| EP0354354B1 (de) | 1994-04-27 |
| EP0354354A3 (en) | 1990-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |