ATE100494T1 - Kontrollsysteme fuer rekombinant-manipulationen. - Google Patents
Kontrollsysteme fuer rekombinant-manipulationen.Info
- Publication number
- ATE100494T1 ATE100494T1 AT85900939T AT85900939T ATE100494T1 AT E100494 T1 ATE100494 T1 AT E100494T1 AT 85900939 T AT85900939 T AT 85900939T AT 85900939 T AT85900939 T AT 85900939T AT E100494 T1 ATE100494 T1 AT E100494T1
- Authority
- AT
- Austria
- Prior art keywords
- sequences
- cassette
- start codon
- expression
- nrbs
- Prior art date
Links
- 108091081024 Start codon Proteins 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 229940088710 antibiotic agent Drugs 0.000 abstract 2
- 230000004927 fusion Effects 0.000 abstract 2
- 239000003550 marker Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 241000701959 Escherichia virus Lambda Species 0.000 abstract 1
- 108010025815 Kanamycin Kinase Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 102000006646 aminoglycoside phosphotransferase Human genes 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57813384A | 1984-02-08 | 1984-02-08 | |
| US06/602,118 US4784949A (en) | 1984-04-19 | 1984-04-19 | Universal dominant selectable marker cassette |
| US61849984A | 1984-06-08 | 1984-06-08 | |
| US64669384A | 1984-08-31 | 1984-08-31 | |
| US06/685,312 US4711845A (en) | 1984-08-31 | 1984-12-24 | Portable temperature-sensitive control cassette |
| EP85900939A EP0172194B1 (de) | 1984-02-08 | 1985-02-07 | Kontrollsysteme für rekombinant-manipulationen |
| PCT/US1985/000196 WO1985003522A1 (en) | 1984-02-08 | 1985-02-07 | Monitoring and control systems for recombinant manipulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE100494T1 true ATE100494T1 (de) | 1994-02-15 |
Family
ID=27541932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85900939T ATE100494T1 (de) | 1984-02-08 | 1985-02-07 | Kontrollsysteme fuer rekombinant-manipulationen. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0172194B1 (de) |
| JP (1) | JP2595205B2 (de) |
| AT (1) | ATE100494T1 (de) |
| DE (1) | DE3587730T2 (de) |
| WO (1) | WO1985003522A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1339736C (en) * | 1986-10-14 | 1998-03-17 | Shionogi & Co., Ltd. | Method for preparing fusion proteins |
| EP0372005A4 (de) * | 1987-10-30 | 1990-06-26 | Oncogen | Expressionssysteme zur erzeugung von polypeptiden in prokaryotischen zellen. |
| EP0314184B1 (de) * | 1987-10-30 | 1995-12-13 | Bristol-Myers Squibb Company | Expressionsplasmide |
| GR1002113B (en) * | 1988-09-02 | 1996-02-02 | Oncogen | Expression systems for preparation of polypeptides in prokaryotic cells |
| DE3936408A1 (de) * | 1989-11-02 | 1991-05-08 | Merck Patent Gmbh | Ueberexpression von proteinen in rekombinanten wirtszellen |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8000127A (nl) * | 1979-01-15 | 1980-07-17 | Harvard College | Werkwijze voor het vormen van prokaryotische of eukaryotische proteinen alsmede een daarbij toepasbaar gekoppeld gen. |
| DE3110031A1 (de) * | 1980-03-17 | 1982-01-07 | President And Fellows Of Harvard College, Cambridge, Mass. | Verschmolzene gene, ihre herstellung und verwendung derselben |
| ZA811368B (en) * | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
| FI811009A7 (fi) * | 1980-06-06 | 1981-12-07 | Biogen Nv | Parannettuja vektoreita, näiden vektoreiden valmistusmenetelmiä ja kloonattujen geenien ekspressiomeneekspressiomenetelmiä. |
| IL66065A (en) * | 1981-06-22 | 1989-06-30 | Lilly Co Eli | Recombinant dna cloning vectors and the e.coli transformants thereof |
| IL66263A (en) * | 1981-08-10 | 1985-12-31 | Genex Corp | Expression vectors for introducing a gene into a procaryotic organism |
| KR840004164A (ko) * | 1982-03-24 | 1984-10-10 | 구라바야시 이꾸시로 | Dna 및 그의 이용 |
| US5079352A (en) * | 1986-08-22 | 1992-01-07 | Cetus Corporation | Purified thermostable enzyme |
-
1985
- 1985-02-07 DE DE85900939T patent/DE3587730T2/de not_active Expired - Fee Related
- 1985-02-07 WO PCT/US1985/000196 patent/WO1985003522A1/en not_active Ceased
- 1985-02-07 JP JP60500756A patent/JP2595205B2/ja not_active Expired - Lifetime
- 1985-02-07 AT AT85900939T patent/ATE100494T1/de not_active IP Right Cessation
- 1985-02-07 EP EP85900939A patent/EP0172194B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1985003522A1 (en) | 1985-08-15 |
| EP0172194A1 (de) | 1986-02-26 |
| JP2595205B2 (ja) | 1997-04-02 |
| DE3587730T2 (de) | 1994-05-05 |
| EP0172194B1 (de) | 1994-01-19 |
| DE3587730D1 (de) | 1994-03-03 |
| JPS62500212A (ja) | 1987-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner | ||
| REN | Ceased due to non-payment of the annual fee |