ATE100097T1 - Benzoxepin-derivate. - Google Patents
Benzoxepin-derivate.Info
- Publication number
- ATE100097T1 ATE100097T1 AT90302745T AT90302745T ATE100097T1 AT E100097 T1 ATE100097 T1 AT E100097T1 AT 90302745 T AT90302745 T AT 90302745T AT 90302745 T AT90302745 T AT 90302745T AT E100097 T1 ATE100097 T1 AT E100097T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- benzoxepin
- chem
- derivatives
- benzoxepin derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1061040A JP2851054B2 (ja) | 1989-03-15 | 1989-03-15 | ベンズオキセピン誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE100097T1 true ATE100097T1 (de) | 1994-01-15 |
Family
ID=13159742
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90302745T ATE100097T1 (de) | 1989-03-15 | 1990-03-14 | Benzoxepin-derivate. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5041444A (de) |
EP (1) | EP0388188B1 (de) |
JP (1) | JP2851054B2 (de) |
AT (1) | ATE100097T1 (de) |
DE (1) | DE69005861T2 (de) |
DK (1) | DK0388188T3 (de) |
ES (1) | ES2062336T3 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005280112B2 (en) | 2004-08-27 | 2012-07-19 | Infinity Pharmaceuticals, Inc. | Cyclopamine analogues and methods of use thereof |
ITMI20042168A1 (it) * | 2004-11-12 | 2005-02-12 | Erregierre Spa | Processo di preparazione di itopride cloridrato |
TWI433674B (zh) | 2006-12-28 | 2014-04-11 | Infinity Discovery Inc | 環杷明(cyclopamine)類似物類 |
EP2129677B1 (de) | 2007-03-07 | 2014-12-17 | Infinity Discovery, Inc. | Heterocyclische cyclopamin-analoga und verfahren zu ihrer verwendung |
MX2009009429A (es) | 2007-03-07 | 2010-07-05 | Infinity Discovery Inc | Analogos de ciclopamina lactama y metodos de uso de los mismos. |
EP2224807B1 (de) | 2007-12-27 | 2016-11-09 | Infinity Pharmaceuticals, Inc. | Verfahren für stereoselektive reduktion |
ES2475209T3 (es) * | 2008-03-01 | 2014-07-10 | Merck Patent Gmbh | Amidas del ácido 5-oxo-2,3,4,5-tetrahidro-benzo[b]oxepin-4-carbox�lico y amidas del ácido 2,3-dihidrobenzo[b]oxepin-4-carbox�lico para el tratamiento y prevención de la diabetes de tipos 1 y 2. |
AU2010279325B2 (en) | 2009-08-05 | 2016-10-20 | Infinity Pharmaceuticals, Inc. | Enzymatic transamination of cyclopamine analogs |
US9394313B2 (en) | 2010-09-14 | 2016-07-19 | Infinity Pharmaceuticals, Inc. | Transfer hydrogenation of cyclopamine analogs |
WO2016019587A1 (en) * | 2014-08-08 | 2016-02-11 | Merck Sharp & Dohme Corp. | [7, 6]-fused bicyclic antidiabetic compounds |
WO2016196928A1 (en) | 2015-06-04 | 2016-12-08 | PellePharm, Inc. | Topical formulations for delivery of hedgehog inhibitor compounds and use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4766212A (en) * | 1983-02-15 | 1988-08-23 | Merrell Dow Pharmaceuticals Inc. | 2H-[1]benzoxepino[5,4-b]-1,4-oxazine derivatives |
AU597671B2 (en) * | 1986-06-20 | 1990-06-07 | Suntory Limited | 2-Phenylbenzoxepin derivative |
-
1989
- 1989-03-15 JP JP1061040A patent/JP2851054B2/ja not_active Expired - Lifetime
-
1990
- 1990-03-08 US US07/490,327 patent/US5041444A/en not_active Expired - Fee Related
- 1990-03-14 AT AT90302745T patent/ATE100097T1/de not_active IP Right Cessation
- 1990-03-14 ES ES90302745T patent/ES2062336T3/es not_active Expired - Lifetime
- 1990-03-14 EP EP90302745A patent/EP0388188B1/de not_active Expired - Lifetime
- 1990-03-14 DK DK90302745.6T patent/DK0388188T3/da active
- 1990-03-14 DE DE90302745T patent/DE69005861T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH02243687A (ja) | 1990-09-27 |
EP0388188A1 (de) | 1990-09-19 |
DE69005861T2 (de) | 1994-04-28 |
DE69005861D1 (de) | 1994-02-24 |
US5041444A (en) | 1991-08-20 |
JP2851054B2 (ja) | 1999-01-27 |
DK0388188T3 (da) | 1994-02-14 |
EP0388188B1 (de) | 1994-01-12 |
ES2062336T3 (es) | 1994-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |