DK0388188T3 - Benzoxepinderivater - Google Patents

Benzoxepinderivater

Info

Publication number
DK0388188T3
DK0388188T3 DK90302745.6T DK90302745T DK0388188T3 DK 0388188 T3 DK0388188 T3 DK 0388188T3 DK 90302745 T DK90302745 T DK 90302745T DK 0388188 T3 DK0388188 T3 DK 0388188T3
Authority
DK
Denmark
Prior art keywords
formula
chem
benzoxepin
represented
hydrolyzing
Prior art date
Application number
DK90302745.6T
Other languages
English (en)
Inventor
Toshio Tatsuoka
Makoto Shibata
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of DK0388188T3 publication Critical patent/DK0388188T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
DK90302745.6T 1989-03-15 1990-03-14 Benzoxepinderivater DK0388188T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1061040A JP2851054B2 (ja) 1989-03-15 1989-03-15 ベンズオキセピン誘導体

Publications (1)

Publication Number Publication Date
DK0388188T3 true DK0388188T3 (da) 1994-02-14

Family

ID=13159742

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90302745.6T DK0388188T3 (da) 1989-03-15 1990-03-14 Benzoxepinderivater

Country Status (7)

Country Link
US (1) US5041444A (da)
EP (1) EP0388188B1 (da)
JP (1) JP2851054B2 (da)
AT (1) ATE100097T1 (da)
DE (1) DE69005861T2 (da)
DK (1) DK0388188T3 (da)
ES (1) ES2062336T3 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2579078C (en) 2004-08-27 2016-11-22 Infinity Pharmaceuticals, Inc. Cyclopamine analogues and methods of use thereof
ITMI20042168A1 (it) * 2004-11-12 2005-02-12 Erregierre Spa Processo di preparazione di itopride cloridrato
TWI433674B (zh) 2006-12-28 2014-04-11 Infinity Discovery Inc 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類
CA2679845A1 (en) 2007-03-07 2008-09-12 Infinity Discovery, Inc. Cyclopamine lactam analogs and methods of use thereof
NZ579361A (en) 2007-03-07 2012-04-27 Infinity Discovery Inc Heterocyclic cyclopamine analogs and methods of use thereof
AU2008345097A1 (en) 2007-12-27 2009-07-09 Infinity Pharmaceuticals, Inc. Methods for stereoselective reduction
MX2010009536A (es) * 2008-03-01 2010-09-24 Merck Patent Gmbh Amidas de acido 5-oxo-2,3,4,5-tetrahidro-benzo[b]oxepin-4-carboxil ico y amidas de acido 2,3-dihidro-benzo[b]oxepin-4-carboxilico para el tratamiento y la prevension de la diabetes tipo 1 y 2.
CA2769795C (en) 2009-08-05 2020-01-07 Infinity Pharmaceuticals, Inc. Enzymatic transamination of cyclopamine analogs
WO2012037217A1 (en) 2010-09-14 2012-03-22 Infinity Pharmaceuticals, Inc. Transfer hydrogenation of cyclopamine analogs
WO2016019587A1 (en) * 2014-08-08 2016-02-11 Merck Sharp & Dohme Corp. [7, 6]-fused bicyclic antidiabetic compounds
MX2017015681A (es) 2015-06-04 2018-09-11 Pellepharm Inc Formulaciones topicas para suministrar compuestos inhibidores de hedgehog y uso de los mismos.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766212A (en) * 1983-02-15 1988-08-23 Merrell Dow Pharmaceuticals Inc. 2H-[1]benzoxepino[5,4-b]-1,4-oxazine derivatives
AU597671B2 (en) * 1986-06-20 1990-06-07 Suntory Limited 2-Phenylbenzoxepin derivative

Also Published As

Publication number Publication date
EP0388188A1 (en) 1990-09-19
DE69005861T2 (de) 1994-04-28
US5041444A (en) 1991-08-20
DE69005861D1 (de) 1994-02-24
ATE100097T1 (de) 1994-01-15
JP2851054B2 (ja) 1999-01-27
EP0388188B1 (en) 1994-01-12
JPH02243687A (ja) 1990-09-27
ES2062336T3 (es) 1994-12-16

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