ATA53984A - Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen - Google Patents

Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Info

Publication number
ATA53984A
ATA53984A AT84539A AT53984A ATA53984A AT A53984 A ATA53984 A AT A53984A AT 84539 A AT84539 A AT 84539A AT 53984 A AT53984 A AT 53984A AT A53984 A ATA53984 A AT A53984A
Authority
AT
Austria
Prior art keywords
diones
salts
producing new
substituted oxazolidin
oxazolidin
Prior art date
Application number
AT84539A
Other languages
English (en)
Other versions
AT376976B (de
Inventor
Rodney Caughren Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/252,962 external-priority patent/US4342771A/en
Priority claimed from AT0328881A external-priority patent/AT376974B/de
Application filed by Pfizer filed Critical Pfizer
Priority to AT0053984A priority Critical patent/AT376976B/de
Publication of ATA53984A publication Critical patent/ATA53984A/de
Application granted granted Critical
Publication of AT376976B publication Critical patent/AT376976B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
AT0053984A 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen AT376976B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0053984A AT376976B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17320680A 1980-07-28 1980-07-28
US06/252,961 US4332952A (en) 1980-07-28 1981-04-23 Hypoglycemic 5-substituted oxazolidine-2,4-diones
US06/252,962 US4342771A (en) 1981-01-02 1981-04-23 Hypoglycemic 5-substituted oxazolidine-2,4-diones
AT0328881A AT376974B (de) 1980-07-28 1981-07-24 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen
AT0053984A AT376976B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Publications (2)

Publication Number Publication Date
ATA53984A true ATA53984A (de) 1984-06-15
AT376976B AT376976B (de) 1985-01-25

Family

ID=26868873

Family Applications (3)

Application Number Title Priority Date Filing Date
AT0053884A AT376975B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen
AT0053984A AT376976B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen
AT0054084A AT376977B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0053884A AT376975B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT0054084A AT376977B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Country Status (3)

Country Link
US (1) US4332952A (de)
AT (3) AT376975B (de)
CS (2) CS237346B2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689336A (en) * 1981-01-02 1987-08-25 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine 2,4-diones
US4423233A (en) * 1981-04-23 1983-12-27 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4430337A (en) 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
CA1334975C (en) * 1987-11-13 1995-03-28 James H. Holms Furan and pyrrole containing lipoxygenase inhibiting compounds
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5498621A (en) * 1992-05-01 1996-03-12 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5401761A (en) * 1993-12-09 1995-03-28 Pfizer, Inc. Thiazolidinedione hypoglycemic agents
TW403748B (en) * 1994-11-02 2000-09-01 Takeda Chemical Industries Ltd An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
ES2277842T3 (es) 1999-06-18 2007-08-01 MERCK & CO., INC. Derivados de ariltiazolidindiona y de ariloxazolidindiona.
US6399640B1 (en) 1999-06-18 2002-06-04 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
US6638929B2 (en) 1999-12-29 2003-10-28 Wyeth Tricyclic protein kinase inhibitors
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
EP3081214A3 (de) 2003-08-29 2016-11-16 The Brigham And Women's Hospital, Inc. Zellnekrosehemmer
EP2381775A4 (de) 2008-12-23 2012-08-15 Harvard College Kleinmolekulare nektroptosehemmer
US9725452B2 (en) 2013-03-15 2017-08-08 Presidents And Fellows Of Harvard College Substituted indoles and pyrroles as RIP kinase inhibitors
MX2017007607A (es) 2014-12-11 2018-05-28 Harvard College Inhibidores de necrosis celular y metodos relacionados.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2338220A (en) * 1942-01-31 1944-01-04 Mallinckrodt Chemical Works Process of making oxazolidinediones
US2721197A (en) * 1953-01-05 1955-10-18 Bristol Lab Inc Bicyclic lactams
US3699229A (en) * 1970-12-18 1972-10-17 Abbott Lab 2-oxo-5-phenyl-4-oxazolidinone as an anti-depressant agent
DE2813873A1 (de) * 1978-03-31 1979-10-11 Basf Ag Verfahren zur herstellung von oxazolidin-2,4-dionen

Also Published As

Publication number Publication date
CS803283A2 (en) 1984-12-14
US4332952A (en) 1982-06-01
AT376975B (de) 1985-01-25
CS803483A2 (en) 1984-12-14
ATA54084A (de) 1984-06-15
CS237348B2 (en) 1985-07-16
ATA53884A (de) 1984-06-15
AT376977B (de) 1985-01-25
AT376976B (de) 1985-01-25
CS237346B2 (en) 1985-07-16

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties