ATA53884A - Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen - Google Patents

Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Info

Publication number
ATA53884A
ATA53884A AT0053884A AT53884A ATA53884A AT A53884 A ATA53884 A AT A53884A AT 0053884 A AT0053884 A AT 0053884A AT 53884 A AT53884 A AT 53884A AT A53884 A ATA53884 A AT A53884A
Authority
AT
Austria
Prior art keywords
diones
salts
producing new
substituted oxazolidin
oxazolidin
Prior art date
Application number
AT0053884A
Other languages
English (en)
Other versions
AT376975B (de
Inventor
Rodney Caughren Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/252,962 external-priority patent/US4342771A/en
Priority claimed from AT0328881A external-priority patent/AT376974B/de
Application filed by Pfizer filed Critical Pfizer
Priority to AT0053884A priority Critical patent/AT376975B/de
Publication of ATA53884A publication Critical patent/ATA53884A/de
Application granted granted Critical
Publication of AT376975B publication Critical patent/AT376975B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0053884A 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen AT376975B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0053884A AT376975B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17320680A 1980-07-28 1980-07-28
US06/252,962 US4342771A (en) 1981-01-02 1981-04-23 Hypoglycemic 5-substituted oxazolidine-2,4-diones
US06/252,961 US4332952A (en) 1980-07-28 1981-04-23 Hypoglycemic 5-substituted oxazolidine-2,4-diones
AT0328881A AT376974B (de) 1980-07-28 1981-07-24 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen
AT0053884A AT376975B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Publications (2)

Publication Number Publication Date
ATA53884A true ATA53884A (de) 1984-06-15
AT376975B AT376975B (de) 1985-01-25

Family

ID=26868873

Family Applications (3)

Application Number Title Priority Date Filing Date
AT0053984A AT376976B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen
AT0053884A AT376975B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen
AT0054084A AT376977B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0053984A AT376976B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT0054084A AT376977B (de) 1980-07-28 1984-02-17 Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen

Country Status (3)

Country Link
US (1) US4332952A (de)
AT (3) AT376976B (de)
CS (2) CS237346B2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689336A (en) * 1981-01-02 1987-08-25 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine 2,4-diones
US4423233A (en) * 1981-04-23 1983-12-27 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4430337A (en) 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
CA1334975C (en) * 1987-11-13 1995-03-28 James H. Holms Furan and pyrrole containing lipoxygenase inhibiting compounds
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5498621A (en) * 1992-05-01 1996-03-12 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5401761A (en) * 1993-12-09 1995-03-28 Pfizer, Inc. Thiazolidinedione hypoglycemic agents
TW403748B (en) * 1994-11-02 2000-09-01 Takeda Chemical Industries Ltd An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
US6380191B1 (en) 1999-06-18 2002-04-30 Merck & Co. Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
CA2376919C (en) 1999-06-18 2008-11-04 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
US6638929B2 (en) * 1999-12-29 2003-10-28 Wyeth Tricyclic protein kinase inhibitors
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
CA2536622C (en) * 2003-08-29 2014-02-11 The Brigham And Women's Hospital, Inc. Inhibitors of cellular necrosis
CA2772760A1 (en) 2008-12-23 2010-07-01 President And Fellows Of Harvard College Small molecule inhibitors of necroptosis
US20160024098A1 (en) 2013-03-15 2016-01-28 President And Fellows Of Harvard College Hybrid necroptosis inhibitors
EP3229807A4 (de) 2014-12-11 2018-10-17 President and Fellows of Harvard College Hemmer von zellulärer nekrose und zugehörige verfahren
WO2025196206A1 (en) * 2024-03-20 2025-09-25 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2338220A (en) * 1942-01-31 1944-01-04 Mallinckrodt Chemical Works Process of making oxazolidinediones
US2721197A (en) * 1953-01-05 1955-10-18 Bristol Lab Inc Bicyclic lactams
US3699229A (en) * 1970-12-18 1972-10-17 Abbott Lab 2-oxo-5-phenyl-4-oxazolidinone as an anti-depressant agent
DE2813873A1 (de) * 1978-03-31 1979-10-11 Basf Ag Verfahren zur herstellung von oxazolidin-2,4-dionen

Also Published As

Publication number Publication date
CS237348B2 (en) 1985-07-16
CS803283A2 (en) 1984-12-14
CS803483A2 (en) 1984-12-14
ATA54084A (de) 1984-06-15
AT376977B (de) 1985-01-25
AT376975B (de) 1985-01-25
AT376976B (de) 1985-01-25
US4332952A (en) 1982-06-01
CS237346B2 (en) 1985-07-16
ATA53984A (de) 1984-06-15

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time
REN Ceased due to non-payment of the annual fee