AT59697B - Process for the preparation of a new yohimbine salt. - Google Patents

Process for the preparation of a new yohimbine salt.

Info

Publication number
AT59697B
AT59697B AT59697DA AT59697B AT 59697 B AT59697 B AT 59697B AT 59697D A AT59697D A AT 59697DA AT 59697 B AT59697 B AT 59697B
Authority
AT
Austria
Prior art keywords
yohimbine
salt
new
preparation
acid
Prior art date
Application number
Other languages
German (de)
Original Assignee
Chem Fab Dr V Kereszty Dr Wolf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Fab Dr V Kereszty Dr Wolf filed Critical Chem Fab Dr V Kereszty Dr Wolf
Application granted granted Critical
Publication of AT59697B publication Critical patent/AT59697B/en

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

   <Desc/Clms Page number 1> 
 



  Verfahren zur Darstellung eines neuen Yohimbinsalzes. 



   Das am meisten gebräuchliche Salz des Yohimbins, das salzsaure Yohimbin, ist wegen seiner Schwerlöslichkeit schwierig dosierbar. Andererseits sind die   n) it Zitronen-   säure, Milchsäure, Weinsäure, Glykolsäure usw. gebildeten, in Wasser gut   löslichen   Yohirnbinsalze wenig beständig, da sie Neigung   haben,   sich in laktidartige Verbindungen umzuwandeln. Hingegen ist das gemäss dem vorliegenden Verfahren dargestellte, azetylsalizylsaure Yohimbin einerseits leicht löslich, andererseits aber auch beständig. 



   Die neue Verbindung ist feinkristallinisch, zersetzt   sxh   bei 75  und ist insbesondere 
 EMI1.1 
   Hase aus.   



   Das azetylsalizylsaure Yohimbin wird durch Vermengen von   äquimoleknlare Slengen   von   Azotylsalizylsäure   bzw. Yohimbin enthaltenden Lösungen und Kristallisieren des Produktes gewonnen. Man löst z. B. Azetylsalizylsäure in trockenem   Äther,   vermengt diese Lösung 
 EMI1.2 
   kristallisierende   Produkt durch Filtrieren von der Flüssigkeit und trocknet es auf Tonplatten. 

**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.



   <Desc / Clms Page number 1>
 



  Process for the preparation of a new yohimbine salt.



   The most common yohimbine salt, hydrochloric acid yohimbine, is difficult to dose because of its poor solubility. On the other hand, the yohirnbine salts formed by citric acid, lactic acid, tartaric acid, glycolic acid, etc., which are readily soluble in water, are not very stable, since they tend to be converted into lactide-like compounds. In contrast, the acetylsalicylic acid yohimbine prepared according to the present method is on the one hand easily soluble, but on the other hand also stable.



   The new compound is finely crystalline, decomposes sxh at 75 and is in particular
 EMI1.1
   Rabbit out.



   The acetylsalicylic acid yohimbine is obtained by mixing equimolar amounts of solutions containing azotylsalicylic acid or yohimbine and crystallizing the product. One solves z. B. acetylsalicylic acid in dry ether, mixes this solution
 EMI1.2
   crystallizing product by filtering off the liquid and drying it on clay plates.

** WARNING ** End of DESC field may overlap beginning of CLMS **.

Claims (1)

PATENT-ANSPRUCH : Verfahren zur Darstellung eines neuen Yohimbinsalzes, und zwar des Salzes der EMI1.3 bzw. Yohimbin enthaltende Lösungen vermengt werden, wonach das Produkt auskristallisiert und durch Filtrieren von der Reaktionsflüssigkeit getrennt werden kann. **WARNUNG** Ende CLMS Feld Kannt Anfang DESC uberlappen**. PATENT CLAIM: Process for the preparation of a new yohimbine salt, namely the salt of EMI1.3 or yohimbine-containing solutions are mixed, after which the product crystallizes out and can be separated from the reaction liquid by filtration. ** WARNING ** End of CLMS field may overlap beginning of DESC **.
AT59697D 1911-04-15 1912-04-15 Process for the preparation of a new yohimbine salt. AT59697B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU59697X 1911-04-15

Publications (1)

Publication Number Publication Date
AT59697B true AT59697B (en) 1913-06-25

Family

ID=10971052

Family Applications (1)

Application Number Title Priority Date Filing Date
AT59697D AT59697B (en) 1911-04-15 1912-04-15 Process for the preparation of a new yohimbine salt.

Country Status (1)

Country Link
AT (1) AT59697B (en)

Similar Documents

Publication Publication Date Title
AT59697B (en) Process for the preparation of a new yohimbine salt.
AT120431B (en) Process for the production of double compounds of urea with sodium iodine.
AT125233B (en) Process for the preparation of salt-like compounds from higher homologues of polyoxybenzenes.
AT124745B (en) Process for the preparation of the mono- or di [β-oxyäthylamine] salt of 3-acetylamino-4-oxybenzolaric acid (1).
DE432420C (en) Process for the preparation of N-methylsulphurous acid salts of secondary amines
AT141169B (en) Process for the production of a spray against plant diseases.
AT154137B (en) Process for the preparation of double compounds of N.N-disubstituted amides of 3,5-dimethyl-isoxazolearboxylic acid- (4).
AT152300B (en) Process for the preparation of guaiacol compounds.
AT113002B (en) Process for the preparation of monoboric acid choline.
AT97145B (en) Process for the preparation of mercury salts of complex bismuthic acids.
AT91678B (en) Process for the production of cold glue from blood.
AT101337B (en) Process for the preparation of a basic bismuth salt of guaiacol-o-carboxylic acid.
DE497909C (en) Process for the preparation of readily soluble salts of N-substituted benzimidazolonarsinic acids
AT117232B (en) Process for the preparation of salts of antimonic acid and its derivatives.
AT112734B (en) Process for the preparation of monocamphorates of the Solanaceae alkaloids.
DE419676C (en) Process for the production of indecomposable and injectable solutions for medicinal purposes containing calcium and silicon compounds at the same time
DE827493C (en) Process for the manufacture of products of the thiosemicarbazone series
DE531009C (en) Process for the preparation of compounds of the higher homologues of polyoxybenzenes
AT77317B (en) Process for the preparation of mercury solutions suitable for injection.
DE765191C (en) Process for the production of solid, water-soluble aluminum acetate
AT69849B (en) Process for the preparation of esters of oxyquinolines.
DE541169C (en) Process for the production of mercury compounds from humic acids
AT64972B (en) Process for the preparation of hexamethylenetetramine salts of α-phenylquinoline-γ-carboxylic acids.
AT235260B (en) Process for the preparation of new derivatives of glycinamide
AT70829B (en) Process for the preparation of amino acid esters.