AT373246B - Neues verfahren zur herstellung von 6-piperidino- 2,4-diaminopyrimidin-3-oxid - Google Patents

Neues verfahren zur herstellung von 6-piperidino- 2,4-diaminopyrimidin-3-oxid

Info

Publication number
AT373246B
AT373246B AT0689879A AT689879A AT373246B AT 373246 B AT373246 B AT 373246B AT 0689879 A AT0689879 A AT 0689879A AT 689879 A AT689879 A AT 689879A AT 373246 B AT373246 B AT 373246B
Authority
AT
Austria
Prior art keywords
diaminopyrimidin
piperidino
oxide
producing
new method
Prior art date
Application number
AT0689879A
Other languages
German (de)
English (en)
Other versions
ATA689879A (de
Inventor
Andras Vedres
Csaba Dr Szantay
Gyula Balogh
Judit Dr Horvath
Tamas Mester
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ATA689879A publication Critical patent/ATA689879A/de
Application granted granted Critical
Publication of AT373246B publication Critical patent/AT373246B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50Three nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT0689879A 1978-10-27 1979-10-23 Neues verfahren zur herstellung von 6-piperidino- 2,4-diaminopyrimidin-3-oxid AT373246B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU78EE2594A HU177601B (en) 1978-10-27 1978-10-27 New process for preparing 6-piperidino-2,4-diamino-pyrimidine-3-oxide

Publications (2)

Publication Number Publication Date
ATA689879A ATA689879A (de) 1983-05-15
AT373246B true AT373246B (de) 1983-12-27

Family

ID=10995794

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0689879A AT373246B (de) 1978-10-27 1979-10-23 Neues verfahren zur herstellung von 6-piperidino- 2,4-diaminopyrimidin-3-oxid

Country Status (14)

Country Link
JP (1) JPS5559172A (es)
AT (1) AT373246B (es)
CH (1) CH642365A5 (es)
CS (1) CS213398B2 (es)
DE (1) DE2943161A1 (es)
DK (1) DK454579A (es)
ES (1) ES485457A1 (es)
FI (1) FI793307A (es)
GB (1) GB2032434B (es)
HU (1) HU177601B (es)
PL (1) PL119712B1 (es)
SE (1) SE432596B (es)
SU (1) SU913942A3 (es)
YU (1) YU262579A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1179344A (en) * 1981-07-15 1984-12-11 Jean-Claude Muller Process for the preparation of 6-¬3,6-dihydro-1(2h)- pyridyl| pyrimidine-3-oxides
CH649291A5 (de) * 1982-03-16 1985-05-15 Hoffmann La Roche Dicarbamate.
HU196061B (en) * 1986-07-10 1988-09-28 Richter Gedeon Vegyeszet Process for production of pirimidine-derivatives
HU196067B (en) * 1986-07-10 1988-09-28 Richter Gedeon Vegyeszet Process for production of 6-amin-1,2-dihydro-1-hydroxi-2-imino-4-piperidin-piramidin
FI864046A (fi) * 1986-10-07 1988-04-08 Farmos Oy Foerfarande foer framstaellning av en terapeutiskt aktiv foerening.
LU86958A1 (fr) * 1987-07-31 1989-03-08 Oreal Sels d'acide thiamorpholinone carboxylique et de derives de diamino-2,4 pyrimidine,leur utilisation en cosmetique et pharmacie
LU86960A1 (fr) * 1987-07-31 1989-03-08 Oreal Procede de preparation de piperidino-6 diamino-2,4 pyrimidine oxyde-3 et composes nouveaux
US4959475A (en) * 1989-01-04 1990-09-25 Lonza Ltd. Process for the production of 2,4-diamino-6-piperidinyl-pyrimidine-3-N-oxide

Also Published As

Publication number Publication date
HU177601B (en) 1981-11-28
CS213398B2 (en) 1982-04-09
DE2943161A1 (de) 1980-05-08
YU262579A (en) 1983-01-21
SU913942A3 (en) 1982-03-15
DK454579A (da) 1980-04-28
SE432596B (sv) 1984-04-09
FI793307A (fi) 1980-04-28
CH642365A5 (de) 1984-04-13
PL219242A1 (es) 1980-06-16
PL119712B1 (en) 1982-01-30
ATA689879A (de) 1983-05-15
GB2032434A (en) 1980-05-08
JPS5559172A (en) 1980-05-02
SE7908629L (sv) 1980-04-28
GB2032434B (en) 1982-11-17
ES485457A1 (es) 1980-10-01

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee