AT370107B - Verfahren zur herstellung von 7-(substituierten) amino-3-substituierten-thiomethyl-delta3-cephem -4-carbonsaeuren - Google Patents

Verfahren zur herstellung von 7-(substituierten) amino-3-substituierten-thiomethyl-delta3-cephem -4-carbonsaeuren

Info

Publication number
AT370107B
AT370107B AT0472779A AT472779A AT370107B AT 370107 B AT370107 B AT 370107B AT 0472779 A AT0472779 A AT 0472779A AT 472779 A AT472779 A AT 472779A AT 370107 B AT370107 B AT 370107B
Authority
AT
Austria
Prior art keywords
substituted
delta3
cephem
thiomethyl
amino
Prior art date
Application number
AT0472779A
Other languages
English (en)
Other versions
ATA472779A (de
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of ATA472779A publication Critical patent/ATA472779A/de
Application granted granted Critical
Publication of AT370107B publication Critical patent/AT370107B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT0472779A 1978-07-06 1979-07-06 Verfahren zur herstellung von 7-(substituierten) amino-3-substituierten-thiomethyl-delta3-cephem -4-carbonsaeuren AT370107B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53082377A JPS6027677B2 (ja) 1978-07-06 1978-07-06 ７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法

Publications (2)

Publication Number Publication Date
ATA472779A ATA472779A (de) 1981-10-15
AT370107B true AT370107B (de) 1983-03-10

Family

ID=13772884

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0472779A AT370107B (de) 1978-07-06 1979-07-06 Verfahren zur herstellung von 7-(substituierten) amino-3-substituierten-thiomethyl-delta3-cephem -4-carbonsaeuren

Country Status (33)

Country Link
US (1) US4312986A (de)
JP (1) JPS6027677B2 (de)
AR (1) AR225289A1 (de)
AT (1) AT370107B (de)
AU (1) AU515683B2 (de)
BE (1) BE877504A (de)
BG (1) BG49615A3 (de)
CA (1) CA1139744A (de)
CH (1) CH641809A5 (de)
CS (1) CS208116B2 (de)
DD (1) DD144778A5 (de)
DE (1) DE2926664C2 (de)
DK (1) DK160942C (de)
EG (1) EG14330A (de)
ES (1) ES482252A1 (de)
FI (1) FI74967C (de)
FR (1) FR2430423A1 (de)
GB (1) GB2027429B (de)
GR (1) GR72517B (de)
HK (1) HK8385A (de)
HU (1) HU179804B (de)
IN (1) IN151439B (de)
IT (1) IT1118889B (de)
KE (1) KE3424A (de)
MX (1) MX5545E (de)
NL (1) NL182146C (de)
NO (1) NO152653C (de)
NZ (1) NZ190938A (de)
PL (1) PL123459B1 (de)
RO (1) RO78358A (de)
SE (1) SE444935B (de)
SU (1) SU1105116A3 (de)
YU (1) YU42948B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543043A (en) * 1978-09-22 1980-03-26 Sankyo Co Ltd Preparation of 3-substituted thiomethylcephalosporin derivative
JPS55139387A (en) * 1979-04-19 1980-10-31 Yamanouchi Pharmaceut Co Ltd Novel synthetic method of 7-amino-3-heterocyclic thiomethyl-delta3-carboxylic acids
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
EP0051824B1 (de) * 1980-11-11 1986-01-15 Takeda Chemical Industries, Ltd. Verfahren zur Herstellung von 7-Aminocephem-Verbindungen
JPS6052754B2 (ja) * 1981-01-29 1985-11-21 山之内製薬株式会社 ７−アミノ−３−ハロゲノメチル−△↑３−セフェム−４−カルボン酸類およびその製法
JPS57128705A (en) * 1981-02-04 1982-08-10 Mitsui Petrochem Ind Ltd Vapor-phase polymerizing method of olefin
JPS58986A (ja) * 1981-05-07 1983-01-06 Fujisawa Pharmaceut Co Ltd セフェム化合物
ES8300334A1 (es) * 1981-09-01 1982-11-01 Gema Sa Procedimiento para la preparacion de un acido 7-aminocefa- losporanido-3-substituido
DK163925C (da) * 1981-09-10 1992-09-14 Takeda Chemical Industries Ltd Fremgangsmaade til fremstilling af cephalosporinforbindelser
KR100477763B1 (ko) * 2000-08-16 2005-03-21 주식회사 엔지켐 세파트리진 프로필렌글리콜 중간체의 신규한 제조방법
KR100432425B1 (ko) * 2000-11-16 2004-05-22 씨제이 주식회사 세펨 유도체 또는 그 염의 신규한 제조방법
US7335767B2 (en) * 2002-10-29 2008-02-26 Lupin Limited Method for preparation of ceftiofur and salts thereof
EP2462253B1 (de) 2009-08-07 2021-04-07 Swagelok Company Niedrigtemperaturaufkohlung in einem weichen vakuum
WO2013109415A1 (en) 2012-01-20 2013-07-25 Swagelok Company Concurrent flow of activating gas in low temperature carburization
CN106967091A (zh) * 2017-05-13 2017-07-21 山西千岫制药有限公司 一种头孢替安母核的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795484U (de) 1959-04-21 1959-09-10 Richard Langer Quertraeger fuer laengsdraehte zum abstuetzen von pflanzen, insbesondere weinreben.
NL130098C (de) * 1963-07-15
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
GB1381272A (en) * 1971-01-26 1975-01-22 Glaxo Lab Ltd Cephalosporin compounds
JPS5116436B1 (de) * 1971-05-31 1976-05-24
ZA728331B (en) 1971-12-23 1974-06-26 Lilly Co Eli Preparation of 3-alkylthiomethyl cephalosporins
US3840531A (en) * 1972-03-21 1974-10-08 Lilly Co Eli Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof
CA1015745A (en) 1972-06-27 1977-08-16 Fujisawa Pharmaceutical Co. 3-substituted-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
DK635474A (de) * 1974-02-05 1975-10-13 Ciba Geigy Ag
JPS5111782A (en) 1974-07-16 1976-01-30 Takeda Chemical Industries Ltd 77 aminosefuemujudotaino seizoho
US4150156A (en) * 1975-11-21 1979-04-17 Merck & Co., Inc. 7-(Substituted methyl)-3-(substituted thio)-cephalosporins, derivatives and pharmaceutical compositions containing them
JPS6022719B2 (ja) * 1977-11-24 1985-06-03 富山化学工業株式会社 ７−置換または非置換アミノ−３−置換チオメチルセフェムカルボン酸類の新規製造法
US4144391A (en) * 1977-03-07 1979-03-13 Eli Lilly And Company Cephalosporin displacement reaction

Also Published As

Publication number Publication date
PL216906A1 (de) 1980-04-21
IT7949678A0 (it) 1979-07-06
GB2027429B (en) 1982-12-08
AU515683B2 (en) 1981-04-16
CS208116B2 (en) 1981-08-31
CH641809A5 (de) 1984-03-15
GR72517B (de) 1983-11-16
AR225289A1 (es) 1982-03-15
RO78358A (ro) 1982-02-26
NL182146C (nl) 1988-01-18
JPS559048A (en) 1980-01-22
NL7905246A (nl) 1980-01-08
BG49615A3 (en) 1991-12-16
CA1139744A (en) 1983-01-18
AU4839479A (en) 1980-01-10
KE3424A (en) 1984-08-10
NO152653B (no) 1985-07-22
FR2430423B1 (de) 1983-05-13
US4312986A (en) 1982-01-26
DE2926664C2 (de) 1983-10-20
DK284779A (da) 1980-02-11
NL182146B (nl) 1987-08-17
DE2926664A1 (de) 1980-01-24
MX5545E (es) 1983-10-03
YU161879A (en) 1982-10-31
SE444935B (sv) 1986-05-20
JPS6027677B2 (ja) 1985-06-29
SU1105116A3 (ru) 1984-07-23
NO152653C (no) 1985-10-30
DK160942C (da) 1991-10-21
FI74967C (fi) 1988-04-11
IN151439B (de) 1983-04-23
IT1118889B (it) 1986-03-03
GB2027429A (en) 1980-02-20
DD144778A5 (de) 1980-11-05
FI74967B (fi) 1987-12-31
FR2430423A1 (fr) 1980-02-01
BE877504A (fr) 1980-01-07
NO792237L (no) 1980-01-08
HK8385A (en) 1985-02-08
EG14330A (en) 1983-09-30
NZ190938A (en) 1981-10-19
ATA472779A (de) 1981-10-15
YU42948B (en) 1989-02-28
HU179804B (en) 1982-12-28
PL123459B1 (en) 1982-10-30
DK160942B (da) 1991-05-06
SE7905899L (sv) 1980-01-07
FI792117A (fi) 1980-01-07
ES482252A1 (es) 1980-04-01

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time