AT369654B - Verfahren zur herstellung von arzneimitteln mit entzuendungshemmender wirkung in form von tabletten oder kapseln zur oralen verabreichung - Google Patents

Verfahren zur herstellung von arzneimitteln mit entzuendungshemmender wirkung in form von tabletten oder kapseln zur oralen verabreichung

Info

Publication number
AT369654B
AT369654B AT0808379A AT808379A AT369654B AT 369654 B AT369654 B AT 369654B AT 0808379 A AT0808379 A AT 0808379A AT 808379 A AT808379 A AT 808379A AT 369654 B AT369654 B AT 369654B
Authority
AT
Austria
Prior art keywords
capsules
tablets
production
oral administration
inflammatory activity
Prior art date
Application number
AT0808379A
Other languages
English (en)
Other versions
ATA808379A (de
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of ATA808379A publication Critical patent/ATA808379A/de
Application granted granted Critical
Publication of AT369654B publication Critical patent/AT369654B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AT0808379A 1978-12-27 1979-12-21 Verfahren zur herstellung von arzneimitteln mit entzuendungshemmender wirkung in form von tabletten oder kapseln zur oralen verabreichung AT369654B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2856333A DE2856333C2 (de) 1978-12-27 1978-12-27 Oral einnehmbare Arzneimittel mit entzündungshemmender Wirkung

Publications (2)

Publication Number Publication Date
ATA808379A ATA808379A (de) 1982-06-15
AT369654B true AT369654B (de) 1983-01-25

Family

ID=6058494

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0808379A AT369654B (de) 1978-12-27 1979-12-21 Verfahren zur herstellung von arzneimitteln mit entzuendungshemmender wirkung in form von tabletten oder kapseln zur oralen verabreichung

Country Status (13)

Country Link
US (1) US4332795A (de)
JP (1) JPS5589225A (de)
AT (1) AT369654B (de)
BE (1) BE880830A (de)
CA (1) CA1133395A (de)
CH (1) CH643739A5 (de)
DE (1) DE2856333C2 (de)
FR (1) FR2445146A1 (de)
GB (1) GB2039738B (de)
IT (1) IT1164550B (de)
NL (1) NL7909244A (de)
SE (1) SE448603B (de)
ZA (1) ZA797008B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2914789A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Injizierbare arzneimittel mit entzuendungshemmender wirkung
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
DE2952115C2 (de) * 1979-12-22 1982-05-06 A. Nattermann & Cie GmbH, 5000 Köln Rosmarinsäure-Phospholipid-Komplex
US4437155A (en) 1980-11-14 1984-03-13 Sperry Corporation Cache/disk subsystem with dual aging of cache entries
US4374082A (en) * 1981-08-18 1983-02-15 Richard Hochschild Method for making a pharmaceutical and/or nutritional dosage form
DE3374914D1 (en) * 1982-04-12 1988-01-28 Univ Texas Methods and compositions for treating gastro-intestinal ulcer diesease
GB2119244A (en) * 1982-04-30 1983-11-16 Alza Corp Potassium replacement therapy
US4666893A (en) * 1983-02-15 1987-05-19 St. Thomas Institute Methods of inducing resistance to bacterial and viral infections
CA1237670A (en) * 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
DE3346525C2 (de) * 1983-12-22 1987-03-19 A. Nattermann & Cie GmbH, 5000 Köln Pharmazeutische Zubereitung mit speziellen 1,2-Diacyl-glycero-3-phosphocholinen zur Behandlung von Erkrankungen im Magen-Darmbereich
DE3346526C2 (de) * 1983-12-22 1986-12-11 A. Nattermann & Cie GmbH, 5000 Köln Pharmazeutisches Präparat zur therapeutischen Behandlung von rheumatischen Erkrankungen
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
IL79114A (en) * 1985-08-07 1990-09-17 Allergan Pharma Method and composition for making liposomes
US5283067A (en) * 1987-01-30 1994-02-01 Ciba-Geigy Corporation Parenteral suspensions
US4918063A (en) * 1987-02-17 1990-04-17 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US5043329A (en) * 1987-02-17 1991-08-27 Board Of Regents, University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US5260284A (en) * 1987-02-17 1993-11-09 Board Of Regents, The University Of Texas System Methods employing unique mixtures of polar and neutral lipids and sterol for lung surfactant replacement therapy
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
US4950656A (en) * 1987-02-17 1990-08-21 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US5030452A (en) * 1989-01-12 1991-07-09 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
US5091187A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
US5763422A (en) * 1995-01-27 1998-06-09 Board Of Regents, The University Of Texas System Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein
US5955451A (en) * 1995-05-12 1999-09-21 The University Of Texas System Board Of Regents Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein
EP0855906B1 (de) 1995-10-17 2008-02-20 Jagotec AG Verabreichung unlöslicher arzneistoffe
AUPN766496A0 (en) * 1996-01-22 1996-02-15 University Of New England, The Method and composition for the potentiation of anti-inflammatory drugs
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
AU762246B2 (en) * 1998-02-11 2003-06-19 Rtp Pharma Corporation Method and composition for treatment of inflammatory conditions
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
HK1039458B (zh) 1998-05-29 2006-09-01 Skyepharma Canada Inc. 熱保護微粒組合物及其最終蒸汽滅菌的方法
HK1040195B (zh) 1998-08-19 2006-06-02 Skyepharma Canada Inc. 普鲁泊福的可注射水分散体
AU767154B2 (en) 1998-11-20 2003-10-30 Skyepharma Canada Inc. Dispersible phospholipid stabilized microparticles
CN1174741C (zh) * 1999-09-21 2004-11-10 Rtp药品公司 生物活性物质的表面改性微粒组合物
EP1276465B1 (de) 2000-04-20 2014-03-12 Jagotec AG Verbessertes verfahren zur herstellung wasserunlöslicher arzneistoffpartikel
US6634576B2 (en) 2000-08-31 2003-10-21 Rtp Pharma Inc. Milled particles
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
ES2372746T3 (es) * 2000-09-20 2012-01-26 Jagotec Ag Micropartículas de fibrato estabilizadas.
US20100173876A1 (en) * 2000-12-19 2010-07-08 The Board Of Regents Of The University Of Texas System Oil-based nsaid compositions and methods for making and using same
US20040077604A1 (en) * 2001-12-19 2004-04-22 Lenard Lichtenberger Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity
AU2001259099B2 (en) * 2001-02-22 2005-12-22 Skyepharma Canada Inc. Fibrate-statin combinations with reduced fed-fasted effects
US9730884B2 (en) 2011-09-29 2017-08-15 Plx Opco Inc. pH dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same
JP6103143B1 (ja) * 2015-05-18 2017-03-29 不二製油株式会社 IL−1β産生抑制作用を有する食品添加用組成物
CN115666523A (zh) 2020-03-26 2023-01-31 Plx 奥普科有限公司 能够进行pH依赖性重构的药物载体及其制备和使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL32337C (de) *
IT1044768B (it) * 1969-04-03 1980-04-21 Italeapmaco Spa Supposte contenenti un principio attivo ascorbato di aminofemazione liofilizzato e processo per la loro preparazione

Also Published As

Publication number Publication date
FR2445146A1 (fr) 1980-07-25
DE2856333A1 (de) 1980-08-21
IT1164550B (it) 1987-04-15
JPS6320209B2 (de) 1988-04-26
SE448603B (sv) 1987-03-09
DE2856333C2 (de) 1983-09-22
ZA797008B (en) 1980-12-31
US4332795A (en) 1982-06-01
FR2445146B1 (de) 1983-09-02
CH643739A5 (de) 1984-06-29
SE7910371L (sv) 1980-06-28
BE880830A (fr) 1980-04-16
JPS5589225A (en) 1980-07-05
ATA808379A (de) 1982-06-15
NL7909244A (nl) 1980-07-01
CA1133395A (en) 1982-10-12
IT7928358A0 (it) 1979-12-21
GB2039738A (en) 1980-08-20
GB2039738B (en) 1983-04-13

Similar Documents

Publication Publication Date Title
AT369654B (de) Verfahren zur herstellung von arzneimitteln mit entzuendungshemmender wirkung in form von tabletten oder kapseln zur oralen verabreichung
AT383271B (de) Verfahren zur herstellung von cerebralwirksamen arzneimitteln
DE3485075D1 (de) Pharmazeutische zubereitung zur heilung der erkrankungen der zahnwurzelhaut und verfahren zu deren herstellung.
AT371708B (de) Verfahren zur herstellung von pharmazeutischen einheitsdosierungsformen
EP0004773A3 (en) 17-beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes, their pharmaceutical use and processes for their preparation
ZA795530B (en) Pharmaceutical tablet for oral administration and process for its manufacture
DD129164A5 (de) Verfahren zur herstellung und verpackung von pharmazeutischen dosierungseinheiten in tablettenform
FR2352808A1 (fr) Acides 12-azaprostanoiques utiles comme medicaments
IL52493A0 (en) 5-aroyl-pyrrolopyrrole-1-carboxylic acid derivatives their production and pharmaceutical compositions containing them
FR2351996A1 (fr) Composes 9-(3,5-di-o-acyl-b-d-arabinofuranosyl)-adeniniques, leur procede de preparation et leur application en tant que medicaments
ATA652178A (de) Verfahren zur herstellung von amidinosulfonsaeure- derivaten und von deren salzen pharmazeutische zusammensetzungen
ATA156576A (de) Verfahren zur herstellung von arzneipraparaten
BE845581A (fr) Nouvelles oxazolidinones-(2), leur procede de preparation et leur application en tant que medicaments
LU79124A1 (de) Neue arzneimittelkombinationen und verfahren zu ihrer herstellung
JPS5259161A (en) 1*44dihydroo2*66dimethyll44 phenyll3*55pyridineedicarbonic acid isobuthylmethyl preparation method and medicine thereof
ATA510975A (de) Verfahren zur herstellung von arzneiformen zur enteralen verabreichung
FR2335228A1 (fr) Derives de la 5-fluoro-pyrimidine-4-one et medicament contenant ces substances
BE842969A (fr) Acides et esters thenoylacetiques substitues, leur procede de preparation et leur utilisation comme medicaments hypolipidemiants
AT361630B (de) Verfahren zur herstellung von arzneimitteln
ZA795565B (en) New benzimidazolylcarbamic acid esters their production, and their medicinal use
IL55006A (en) Oxaminic acids and salts and esters thereof,their production and pharmaceutical compositions containing them
FR2295750A1 (fr) Nouvelles benzylpyrimidines utiles en tant que medicaments et leur procede de preparation
AT333276B (de) Verfahren zur herstellung von neuen benzofuran-2-onen oder isochromanonen und deren pharmazeutisch vertraglichen saureadditionssalzen
AT366574B (de) Verfahren zur herstellung von pharmazeutischen praeparaten zur oralen verabreichung
LU79430A1 (de) Verfahren zur herstellung von 2-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphanen,von deren saeureadditionssalzen und diese enthaltenden arzneimitteln

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee