AT360663B - Verfahren zur herstellung von neuen 6,7- -benzomorphanen - Google Patents
Verfahren zur herstellung von neuen 6,7- -benzomorphanenInfo
- Publication number
- AT360663B AT360663B AT137276A AT137276A AT360663B AT 360663 B AT360663 B AT 360663B AT 137276 A AT137276 A AT 137276A AT 137276 A AT137276 A AT 137276A AT 360663 B AT360663 B AT 360663B
- Authority
- AT
- Austria
- Prior art keywords
- benzomorphans
- producing new
- producing
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- One-Way And Automatic Clutches, And Combinations Of Different Clutches (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7891/75A GB1513961A (en) | 1975-02-25 | 1975-02-25 | 6,7-benzomorphans method for their preparation and intermediates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA137276A ATA137276A (de) | 1980-06-15 |
| AT360663B true AT360663B (de) | 1981-01-26 |
Family
ID=9841801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT137276A AT360663B (de) | 1975-02-25 | 1976-02-25 | Verfahren zur herstellung von neuen 6,7- -benzomorphanen |
Country Status (20)
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5381778A (en) * | 1976-12-27 | 1978-07-19 | Toshiharu Nakao | Cloth loop forming apparatus in steaming apparatus |
| NL7804509A (nl) * | 1978-04-26 | 1979-10-30 | Acf Chemiefarma Nv | Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan. |
| DE2828039A1 (de) * | 1978-06-26 | 1980-01-10 | Boehringer Sohn Ingelheim | 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung |
| US4208523A (en) * | 1978-11-30 | 1980-06-17 | Sterling Drug Inc. | 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines |
| NL7907800A (nl) * | 1979-10-23 | 1981-04-27 | Acf Chemiefarma Nv | Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten. |
| US5490436A (en) * | 1994-03-17 | 1996-02-13 | At&T Corp. | Liquid-chamber apparatus for active, dynamic balancing of rotating machinery |
| US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP1506174B1 (en) | 2002-05-17 | 2015-09-30 | Taiwanj Pharmaceuticals Co., Ltd. | Use of naltrexone for treating kidney and liver damage |
| US8017622B2 (en) * | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| JP5451611B2 (ja) * | 2007-07-26 | 2014-03-26 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター |
| AR069207A1 (es) * | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
| JP5769970B2 (ja) * | 2007-11-16 | 2015-08-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用 |
| JP5490014B2 (ja) | 2007-12-11 | 2014-05-14 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤 |
| TW200934490A (en) * | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| CA2711757C (en) * | 2008-02-12 | 2016-07-26 | Boehringer Ingelheim International Gmbh | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| JP5301563B2 (ja) | 2008-05-01 | 2013-09-25 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| TW200950780A (en) | 2008-05-13 | 2009-12-16 | Boehringer Ingelheim Int | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| JP5379160B2 (ja) | 2008-07-25 | 2013-12-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| JP5777030B2 (ja) | 2008-07-25 | 2015-09-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤 |
| MA33216B1 (fr) | 2009-04-30 | 2012-04-02 | Boehringer Ingelheim Int | Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1 |
| JP5670440B2 (ja) | 2009-06-02 | 2015-02-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 |
| WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| JP5456555B2 (ja) | 2010-04-23 | 2014-04-02 | 株式会社マキタ | 電動工具 |
| JP5860042B2 (ja) | 2010-06-16 | 2016-02-16 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用 |
| JP5813106B2 (ja) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 代謝障害の処置のための１１−β−ＨＳＤ１のインヒビターとしてのアザスピロヘキサノン |
| AU2011325286B2 (en) | 2010-11-02 | 2015-04-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
| US8735585B2 (en) | 2011-08-17 | 2014-05-27 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3138603A (en) * | 1958-10-31 | 1964-06-23 | Everette L May | New benzomorphans (methanobenzazocines) and preparation thereof |
| US3372165A (en) * | 1960-12-01 | 1968-03-05 | Sterling Drug Inc | 1, 2, 3, 4, 5, 6-hexahydro-8-hydroxy-2, 6-methano-3-benzazocine derivatives |
| NL156047B (nl) * | 1969-06-04 | 1978-03-15 | Acf Chemiefarma Nv | Werkwijze voor de bereiding van farmaceutische preparaten met analgetische en/of morfine-antagonistische werking, gevormde preparaten, alsmede werkwijze voor de bereiding van daartoe geschikte nieuwe 6,7-benzomorfanen. |
| IE34235B1 (en) * | 1969-06-04 | 1975-03-19 | Acf Chemiefarma Nv | 6,7-benzomorphans and their preparation |
| US3969468A (en) * | 1972-10-31 | 1976-07-13 | Kyowa Hakko Kogyo Co., Ltd. | 2-Amino-1,2,3,4-tetrahydronaphthalene derivatives |
| US4010164A (en) * | 1973-03-28 | 1977-03-01 | Boehringer Ingelheim Gmbh | N-(furyl-methyl)-2-hydroxy-5,9,9-trimethyl-benzomorphans and salts thereof |
| SU511005A3 (ru) * | 1973-10-27 | 1976-04-15 | К.Х.Берингер Зон., (Фирма) | Способ получени (метоксиметилфурилметил)6,7-бензоморфанов или морфинанов |
| US4087532A (en) * | 1974-03-09 | 1978-05-02 | Boehringer Ingelheim Gmbh | Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof |
| US4032529A (en) * | 1974-09-20 | 1977-06-28 | Sterling Drug Inc. | Aminomethanobenzazocine intermediates |
-
1975
- 1975-02-25 GB GB7891/75A patent/GB1513961A/en not_active Expired
-
1976
- 1976-02-05 AU AU10856/76A patent/AU505939B2/en not_active Expired
- 1976-02-09 IL IL48990A patent/IL48990A/xx unknown
- 1976-02-17 DE DE19762606267 patent/DE2606267A1/de not_active Withdrawn
- 1976-02-17 US US05/658,739 patent/US4128548A/en not_active Expired - Lifetime
- 1976-02-19 BE BE164433A patent/BE838708A/xx unknown
- 1976-02-20 IE IE334/76A patent/IE43450B1/en unknown
- 1976-02-23 PH PH18131A patent/PH12974A/en unknown
- 1976-02-23 JP JP1875676A patent/JPS51111550A/ja active Pending
- 1976-02-24 DK DK76176*#A patent/DK76176A/da unknown
- 1976-02-24 ES ES445494A patent/ES445494A1/es not_active Expired
- 1976-02-24 IT IT67415/76A patent/IT1057250B/it active
- 1976-02-24 SE SE7602235A patent/SE7602235L/xx not_active Application Discontinuation
- 1976-02-24 FR FR7605083A patent/FR2302092A1/fr active Granted
- 1976-02-25 HU HU76CE1075A patent/HU173571B/hu unknown
- 1976-02-25 LU LU74431A patent/LU74431A1/xx unknown
- 1976-02-25 AT AT137276A patent/AT360663B/de not_active IP Right Cessation
- 1976-02-25 CH CH234376A patent/CH621115A5/de not_active IP Right Cessation
- 1976-02-25 CA CA246,540A patent/CA1080704A/en not_active Expired
- 1976-02-25 JP JP51019022A patent/JPS51118767A/ja active Pending
- 1976-02-25 NL NL7601924A patent/NL7601924A/xx not_active Application Discontinuation
-
1978
- 1978-07-28 US US05/928,862 patent/US4268673A/en not_active Expired - Lifetime
-
1979
- 1979-11-20 CH CH1036579A patent/CH623572A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH621115A5 (US07714131-20100511-C00024.png) | 1981-01-15 |
| FR2302092A1 (fr) | 1976-09-24 |
| ES445494A1 (es) | 1977-11-01 |
| ATA137276A (de) | 1980-06-15 |
| AU505939B2 (en) | 1979-12-06 |
| IL48990A0 (en) | 1976-04-30 |
| DE2606267A1 (de) | 1976-09-30 |
| CH623572A5 (US07714131-20100511-C00024.png) | 1981-06-15 |
| FR2302092B1 (US07714131-20100511-C00024.png) | 1978-11-10 |
| BE838708A (fr) | 1976-08-19 |
| IL48990A (en) | 1980-01-31 |
| IE43450B1 (en) | 1981-02-25 |
| IT1057250B (it) | 1982-03-10 |
| JPS51111550A (en) | 1976-10-01 |
| AU1085676A (en) | 1977-08-11 |
| US4128548A (en) | 1978-12-05 |
| IE43450L (en) | 1976-08-25 |
| JPS51118767A (en) | 1976-10-18 |
| GB1513961A (en) | 1978-06-14 |
| LU74431A1 (US07714131-20100511-C00024.png) | 1976-08-13 |
| NL7601924A (nl) | 1976-08-27 |
| DK76176A (da) | 1976-08-26 |
| PH12974A (en) | 1979-10-24 |
| CA1080704A (en) | 1980-07-01 |
| SE7602235L (sv) | 1976-08-26 |
| HU173571B (hu) | 1979-06-28 |
| US4268673A (en) | 1981-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |