BE838708A - Nouveaux derives 6,7-benzomorphaniques possedant des proprietes analgesiques - Google Patents

Nouveaux derives 6,7-benzomorphaniques possedant des proprietes analgesiques

Info

Publication number
BE838708A
BE838708A BE164433A BE164433A BE838708A BE 838708 A BE838708 A BE 838708A BE 164433 A BE164433 A BE 164433A BE 164433 A BE164433 A BE 164433A BE 838708 A BE838708 A BE 838708A
Authority
BE
Belgium
Prior art keywords
benzomorphanic
derivatives
new
analgesic properties
analgesic
Prior art date
Application number
BE164433A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE838708A publication Critical patent/BE838708A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • One-Way And Automatic Clutches, And Combinations Of Different Clutches (AREA)
BE164433A 1975-02-25 1976-02-19 Nouveaux derives 6,7-benzomorphaniques possedant des proprietes analgesiques BE838708A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7891/75A GB1513961A (en) 1975-02-25 1975-02-25 6,7-benzomorphans method for their preparation and intermediates

Publications (1)

Publication Number Publication Date
BE838708A true BE838708A (fr) 1976-08-19

Family

ID=9841801

Family Applications (1)

Application Number Title Priority Date Filing Date
BE164433A BE838708A (fr) 1975-02-25 1976-02-19 Nouveaux derives 6,7-benzomorphaniques possedant des proprietes analgesiques

Country Status (20)

Country Link
US (2) US4128548A (fr)
JP (2) JPS51111550A (fr)
AT (1) AT360663B (fr)
AU (1) AU505939B2 (fr)
BE (1) BE838708A (fr)
CA (1) CA1080704A (fr)
CH (2) CH621115A5 (fr)
DE (1) DE2606267A1 (fr)
DK (1) DK76176A (fr)
ES (1) ES445494A1 (fr)
FR (1) FR2302092A1 (fr)
GB (1) GB1513961A (fr)
HU (1) HU173571B (fr)
IE (1) IE43450B1 (fr)
IL (1) IL48990A (fr)
IT (1) IT1057250B (fr)
LU (1) LU74431A1 (fr)
NL (1) NL7601924A (fr)
PH (1) PH12974A (fr)
SE (1) SE7602235L (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5381778A (en) * 1976-12-27 1978-07-19 Toshiharu Nakao Cloth loop forming apparatus in steaming apparatus
NL7804509A (nl) * 1978-04-26 1979-10-30 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
NL7907800A (nl) * 1979-10-23 1981-04-27 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.
US5490436A (en) * 1994-03-17 1996-02-13 At&T Corp. Liquid-chamber apparatus for active, dynamic balancing of rotating machinery
EP2987788A1 (fr) 2002-05-17 2016-02-24 Taiwanj Pharmaceuticals Co., Ltd. Composés opioïdes et de type opioïde et leurs utilisations
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7923454B2 (en) * 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
ATE554078T1 (de) * 2007-07-26 2012-05-15 Vitae Pharmaceuticals Inc Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
CL2008003407A1 (es) * 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
WO2009075835A1 (fr) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc Inhibiteurs cycliques d'urée de la 11-hydroxystéroïde déhydrogénase 1
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
EP2245014B1 (fr) * 2008-02-12 2011-11-02 Boehringer Ingelheim International GmbH Derives d'uree de benzomorphanes et structures associees, medicaments contenant de tels composes et leur utilisation
AR071609A1 (es) 2008-05-01 2010-06-30 Vitae Pharmaceuticals Inc Inhibidores ciclicos de 11(beta) -hidroxiesteroide deshidrogenasa 1
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
WO2010010157A2 (fr) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibiteurs de la 11 bêta-hydroxystéroïde déshydrogénase 1
CA2730499A1 (fr) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibiteurs cycliques de la 11 beta-hydroxysteroide deshydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2438049B1 (fr) 2009-06-02 2014-05-14 Boehringer Ingelheim International GmbH Inhibiteurs cycliques de la 11 béta-hydroxystéroïde déshydrogénase 1
EP2440537A1 (fr) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déshydrogénase 1 basée sur la structure 1,3-oxazinan-2-one
JP5456555B2 (ja) 2010-04-23 2014-04-02 株式会社マキタ 電動工具
EP2582698B1 (fr) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Hétérocycles à 5, 6 et 7 chaînons substitués, médicaments contenant ces composés et leur utilisation
EP2585444B1 (fr) 2010-06-25 2014-10-22 Boehringer Ingelheim International GmbH Azaspirohexanones comme inhibiteurs de 11-beta -hsd1 pour le traitement de troubles métaboliques
WO2012059416A1 (fr) 2010-11-02 2012-05-10 Boehringer Ingelheim International Gmbh Combinaisons pharmaceutiques destinées au traitement de troubles du métabolisme
WO2013025664A1 (fr) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Dérivés d'indénopyridine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3138603A (en) * 1958-10-31 1964-06-23 Everette L May New benzomorphans (methanobenzazocines) and preparation thereof
US3372165A (en) * 1960-12-01 1968-03-05 Sterling Drug Inc 1, 2, 3, 4, 5, 6-hexahydro-8-hydroxy-2, 6-methano-3-benzazocine derivatives
NL156047B (nl) * 1969-06-04 1978-03-15 Acf Chemiefarma Nv Werkwijze voor de bereiding van farmaceutische preparaten met analgetische en/of morfine-antagonistische werking, gevormde preparaten, alsmede werkwijze voor de bereiding van daartoe geschikte nieuwe 6,7-benzomorfanen.
IE34235B1 (en) * 1969-06-04 1975-03-19 Acf Chemiefarma Nv 6,7-benzomorphans and their preparation
CA1010031A (en) * 1972-10-31 1977-05-10 Kentaro Tamaki 6,7-benzomorphan derivatives
US4010164A (en) * 1973-03-28 1977-03-01 Boehringer Ingelheim Gmbh N-(furyl-methyl)-2-hydroxy-5,9,9-trimethyl-benzomorphans and salts thereof
SU511005A3 (ru) * 1973-10-27 1976-04-15 К.Х.Берингер Зон., (Фирма) Способ получени (метоксиметилфурилметил)6,7-бензоморфанов или морфинанов
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
US4032529A (en) * 1974-09-20 1977-06-28 Sterling Drug Inc. Aminomethanobenzazocine intermediates

Also Published As

Publication number Publication date
CH623572A5 (fr) 1981-06-15
AT360663B (de) 1981-01-26
US4268673A (en) 1981-05-19
SE7602235L (sv) 1976-08-26
DK76176A (da) 1976-08-26
DE2606267A1 (de) 1976-09-30
PH12974A (en) 1979-10-24
CA1080704A (fr) 1980-07-01
NL7601924A (nl) 1976-08-27
JPS51118767A (en) 1976-10-18
HU173571B (hu) 1979-06-28
IE43450L (en) 1976-08-25
LU74431A1 (fr) 1976-08-13
AU1085676A (en) 1977-08-11
GB1513961A (en) 1978-06-14
IL48990A0 (en) 1976-04-30
IT1057250B (it) 1982-03-10
JPS51111550A (en) 1976-10-01
CH621115A5 (fr) 1981-01-15
ES445494A1 (es) 1977-11-01
FR2302092A1 (fr) 1976-09-24
US4128548A (en) 1978-12-05
IL48990A (en) 1980-01-31
IE43450B1 (en) 1981-02-25
FR2302092B1 (fr) 1978-11-10
ATA137276A (de) 1980-06-15
AU505939B2 (en) 1979-12-06

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