AT356637B - Verfahren zur herstellung von neuen n-acyl- taurinsalzen - Google Patents
Verfahren zur herstellung von neuen n-acyl- taurinsalzenInfo
- Publication number
- AT356637B AT356637B AT202878A AT202878A AT356637B AT 356637 B AT356637 B AT 356637B AT 202878 A AT202878 A AT 202878A AT 202878 A AT202878 A AT 202878A AT 356637 B AT356637 B AT 356637B
- Authority
- AT
- Austria
- Prior art keywords
- acyl
- producing new
- taurine salts
- taurine
- salts
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
- C07C303/22—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
- C07C309/15—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton the nitrogen atom of at least one of the amino groups being part of any of the groups, X being a hetero atom, Y being any atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7708692A FR2384751A1 (fr) | 1977-03-23 | 1977-03-23 | Nouveaux derives de la taurine a activite neuro-musculaire renforcee |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA202878A ATA202878A (de) | 1979-10-15 |
| AT356637B true AT356637B (de) | 1980-05-12 |
Family
ID=9188473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT202878A AT356637B (de) | 1977-03-23 | 1978-03-22 | Verfahren zur herstellung von neuen n-acyl- taurinsalzen |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US4199601A (enExample) |
| JP (1) | JPS53149928A (enExample) |
| AT (1) | AT356637B (enExample) |
| AU (1) | AU523705B2 (enExample) |
| BE (1) | BE865163A (enExample) |
| CA (1) | CA1095930A (enExample) |
| CH (1) | CH629479A5 (enExample) |
| DE (1) | DE2810918C2 (enExample) |
| ES (1) | ES468201A1 (enExample) |
| FR (1) | FR2384751A1 (enExample) |
| GB (1) | GB1599962A (enExample) |
| GR (1) | GR62093B (enExample) |
| IT (1) | IT1111455B (enExample) |
| NL (1) | NL7803131A (enExample) |
| OA (1) | OA05914A (enExample) |
| SE (1) | SE443781B (enExample) |
| ZA (1) | ZA781697B (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2457281A1 (fr) * | 1979-05-23 | 1980-12-19 | Meram Lab | Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee |
| US4915685A (en) * | 1986-03-19 | 1990-04-10 | Petelenz Tomasz J | Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange |
| US5602150A (en) * | 1992-10-02 | 1997-02-11 | Research Foundation For Mental Hygiene, Inc. | Treatment of central nervous system disorders associated with psychotic behavior and dementia with a combination of neuroleptic drugs and taurine, or derivatives thereof, to prevent the development of tardive dyskinesia |
| US6099869A (en) | 1995-04-18 | 2000-08-08 | Nutrition 21 | Calcium taurate and antihypertensive drug for hypertension |
| IT1291127B1 (it) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica |
| ATE251129T1 (de) * | 1998-01-27 | 2003-10-15 | Merck Sante Sas | Derivatives of aminoalkane sulphonic, phosphonic and phosphinic acids, their preparation and their use as medicaments |
| CA2369997C (en) * | 1999-04-28 | 2009-11-17 | Queen's University At Kingston | Compositions and methods for treating amyloidosis |
| US6562836B1 (en) | 1999-05-24 | 2003-05-13 | Queen's University Of Kingston | Methods and compounds for inhibiting amyloid deposits |
| US6881750B2 (en) * | 2003-03-04 | 2005-04-19 | Nutrition Corp. Of America, Ltd. | Potassium taurate bicarbonate and ascorbate |
| US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) * | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| AU2005310986A1 (en) * | 2004-11-12 | 2006-06-08 | Bellus Health (International) Limited | Methods and fluorinated compositions for treating amyloid-related diseases |
| AU2005310979A1 (en) * | 2004-11-16 | 2006-06-08 | Bellus Health (International) Limited | Compounds for the treatment of CNS and amyloid associated diseases |
| FR2878160B1 (fr) * | 2004-11-19 | 2008-07-25 | Jean Pierre Durlach | Utilisation du n-acetyl-taurinate de magnesium pour la preparation de medicaments inhibiteurs de l'hypersensiblite photique |
| EP1836161B1 (en) * | 2004-12-22 | 2016-07-20 | BHI Limited Partnership | Methods and compositions for treating amyloid-related diseases |
| SI2089417T1 (sl) | 2006-10-12 | 2015-04-30 | Bhi Limited Partnership | Metode, spojine, sestavki in vektorji za dostavo 3-amino-1-propansulfonske kisline |
| TW200924746A (en) * | 2007-09-07 | 2009-06-16 | Xenoport Inc | Complex pantoic acid ester neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use |
| WO2009033079A1 (en) * | 2007-09-07 | 2009-03-12 | Xenoport, Inc. | Externally masked neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use |
| US20090099253A1 (en) * | 2007-10-15 | 2009-04-16 | Xenoport, Inc. | Internally Masked Neopentyl Sulfonyl Ester Cyclization Release Prodrugs of Acamprosate, Compositions Thereof, and Methods of Use |
| FR2927809B1 (fr) | 2008-02-26 | 2011-01-14 | Tri Inov | Nouvelle utilisation de n-acetyl-taurinate de zinc. |
| RU2453310C1 (ru) * | 2010-12-09 | 2012-06-20 | Открытое акционерное общество "Всероссийский научный центр по безопасности биологически активных веществ" (ОАО "ВНЦ БАВ") | Средство, обладающее нейропротекторным действием в условиях ишемического поражения мозга и гипоксии, представляющее собой 2-аминоэтансульфонат магния, фармацевтические композиции |
| FR2973702B1 (fr) | 2011-04-08 | 2013-04-26 | Tri Inov | N-acetyl-taurinate de zinc pour le traitement du cancer de la prostate |
| BR112014012918A2 (pt) * | 2011-11-29 | 2017-06-13 | Basf Se | processo para preparar um sal de ácido, ácido, sal de sódio ácido, e, uso de um ácido |
| MX365366B (es) | 2015-06-17 | 2019-05-30 | Jean Profet Margaret | Formulaciones tópicas y orales que comprenden taurina y magnesio para la prevención y el tratamiento del acné. |
| CN112516123B (zh) * | 2015-12-25 | 2022-07-19 | 北京乳凝创智生物技术研发中心（有限合伙） | 一种保健品外用制剂 |
| BE1025644B1 (fr) * | 2017-10-13 | 2019-05-15 | Synapharm Industrial Synthesis | Compose pour le traitement d'une maladie ou d'un trouble du systeme nerveux central chez un sujet en stimulant et/ou en restaurant la plasticite neuronale |
| BE1025645B1 (fr) * | 2017-10-13 | 2019-05-15 | Synapharm Industrial Synthesis | Compose pour le traitement de la neurotoxicite due a l'hyperexcitabilite des recepteurs glutamatergiques ionotropes |
| EP3738588A1 (en) | 2019-05-13 | 2020-11-18 | Margaret Jean Profet | Topical and oral formulations comprising taurine and magnesium for use in the treatment of rosacea |
| WO2020229443A1 (fr) | 2019-05-16 | 2020-11-19 | Synapharm Industrial Synthesis | Composé et composition pour utilisation dans le traitement du syndrome prémenstruel et/ou du trouble dysphorique prémenstruel |
| ES2917623T3 (es) | 2019-05-16 | 2022-07-11 | Synapharm Ind Synthesis | Compuesto y composición para uso en el tratamiento del síndrome premenstrual y/o del trastorno disfórico premenstrual |
| BE1026955B1 (fr) * | 2019-06-11 | 2020-08-04 | Synapharm Ind Synthesis | Procédé de fabrication de N-acétyl-taurinate de magnésium |
| RU2730835C1 (ru) * | 2019-10-23 | 2020-08-26 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации ФГБОУ ВО ВолгГМУ МЗ РФ | Дикалиевая соль N-(3-гидроксибензоил)таурина, обладающая антиагрегантной и антитромботической активностью в сочетании с церебропротективным действием |
| RU2731106C1 (ru) * | 2019-10-23 | 2020-08-28 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации ФГБОУ ВО ВолгГМУ МЗ РФ | Дикалиевая соль N-(4-гидроксибензоил)таурина, обладающая антиагрегантной и антитромботической активностью |
| WO2021245697A1 (en) | 2020-06-01 | 2021-12-09 | Celagenex Research (India) Pvt. Ltd. | Novel synergistic medicinal compositions for treating dysfunctional d-serine signaling |
| WO2026013679A1 (en) * | 2024-07-11 | 2026-01-15 | Celagenex Research (India) Pvt. Ltd. | A conjugate compound for regulation of mbp expression and novel in-situ process for preparation thereof. |
| CN119504517B (zh) * | 2025-01-22 | 2025-04-18 | 浙江天启生化股份有限公司 | 一种乙酰牛磺酸镁的制备方法 |
| WO2026162765A1 (en) * | 2025-01-31 | 2026-08-06 | Synapharm Industrial Synthesis | Compound and compositions for weight management and related conditions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3232968A (en) * | 1959-12-01 | 1966-02-01 | Gen Aniline & Film Corp | Process for preparing n-acyl taurates using hypophosphorous acid as catalyst |
| US3344174A (en) * | 1962-08-21 | 1967-09-26 | Monsanto Co | Vicinal acylamido sulfonate compounds |
| DE1256650B (de) * | 1965-08-07 | 1967-12-21 | Dr Dieter Arlt | Verfahren zur Herstellung von N-acylierten 2-Amino-alkan-sulfonsaeuren-(1) bzw. von 2-Amino-alkan-sulfonsaeuren-(1) |
| US3544597A (en) * | 1969-06-12 | 1970-12-01 | Rohm & Haas | Process for manufacturing sulfonated amides |
| US3960918A (en) * | 1973-06-26 | 1976-06-01 | The Lubrizol Corporation | Preparation of esters of amidoalkanesulfonic acids |
-
1977
- 1977-03-23 FR FR7708692A patent/FR2384751A1/fr active Granted
-
1978
- 1978-03-06 GR GR55625A patent/GR62093B/el unknown
- 1978-03-14 DE DE2810918A patent/DE2810918C2/de not_active Expired
- 1978-03-16 SE SE7803032A patent/SE443781B/sv not_active IP Right Cessation
- 1978-03-17 GB GB10688/78A patent/GB1599962A/en not_active Expired
- 1978-03-20 OA OA56441A patent/OA05914A/xx unknown
- 1978-03-20 CA CA299,464A patent/CA1095930A/en not_active Expired
- 1978-03-20 US US05/888,202 patent/US4199601A/en not_active Expired - Lifetime
- 1978-03-22 AT AT202878A patent/AT356637B/de not_active IP Right Cessation
- 1978-03-22 IT IT67631/78A patent/IT1111455B/it active
- 1978-03-22 ES ES468201A patent/ES468201A1/es not_active Expired
- 1978-03-22 CH CH312778A patent/CH629479A5/fr not_active IP Right Cessation
- 1978-03-22 BE BE2056782A patent/BE865163A/xx not_active IP Right Cessation
- 1978-03-23 ZA ZA00781697A patent/ZA781697B/xx unknown
- 1978-03-23 NL NL7803131A patent/NL7803131A/xx not_active Application Discontinuation
- 1978-03-23 JP JP3398978A patent/JPS53149928A/ja active Granted
- 1978-03-31 AU AU34634/78A patent/AU523705B2/en not_active Expired
-
1979
- 1979-12-14 US US06/103,729 patent/US4271189A/en not_active Expired - Lifetime
- 1979-12-14 US US06/103,730 patent/US4267194A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IT1111455B (it) | 1986-01-13 |
| JPS53149928A (en) | 1978-12-27 |
| AU523705B2 (en) | 1982-08-12 |
| GR62093B (en) | 1979-02-22 |
| ZA781697B (en) | 1979-03-28 |
| IT7867631A0 (it) | 1978-03-22 |
| OA05914A (fr) | 1981-06-30 |
| SE443781B (sv) | 1986-03-10 |
| FR2384751A1 (fr) | 1978-10-20 |
| DE2810918C2 (de) | 1985-06-20 |
| CA1095930A (en) | 1981-02-17 |
| NL7803131A (nl) | 1978-09-26 |
| GB1599962A (en) | 1981-10-07 |
| ES468201A1 (es) | 1978-12-01 |
| BE865163A (fr) | 1978-09-22 |
| US4271189A (en) | 1981-06-02 |
| JPS6256867B2 (enExample) | 1987-11-27 |
| SE7803032L (sv) | 1978-09-24 |
| ATA202878A (de) | 1979-10-15 |
| US4199601A (en) | 1980-04-22 |
| FR2384751B1 (enExample) | 1979-07-20 |
| DE2810918A1 (de) | 1978-09-28 |
| CH629479A5 (fr) | 1982-04-30 |
| AU3463478A (en) | 1979-10-04 |
| US4267194A (en) | 1981-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EIH | Change in the person of patent owner | ||
| ELJ | Ceased due to non-payment of the annual fee |