AT346321B - Verfahren zur herstellung von neuen 4'- substituierten benzoylphenylnaphthalinen und den saeureadditionssalzen hievon - Google Patents

Verfahren zur herstellung von neuen 4'- substituierten benzoylphenylnaphthalinen und den saeureadditionssalzen hievon

Info

Publication number
AT346321B
AT346321B AT800576A AT800576A AT346321B AT 346321 B AT346321 B AT 346321B AT 800576 A AT800576 A AT 800576A AT 800576 A AT800576 A AT 800576A AT 346321 B AT346321 B AT 346321B
Authority
AT
Austria
Prior art keywords
benzoylphenylnaphthalines
substituted
producing new
additional salts
acid additional
Prior art date
Application number
AT800576A
Other languages
German (de)
English (en)
Other versions
ATA800576A (de
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT122676A priority Critical patent/AT346723B/de
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ATA800576A publication Critical patent/ATA800576A/de
Application granted granted Critical
Publication of AT346321B publication Critical patent/AT346321B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/455—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265—Citric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT800576A 1973-11-07 1976-10-28 Verfahren zur herstellung von neuen 4'- substituierten benzoylphenylnaphthalinen und den saeureadditionssalzen hievon AT346321B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT122676A AT346723B (de) 1973-11-07 1976-02-20 Aufschnittschneidemaschine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62599175A 1975-10-28 1975-10-28

Publications (2)

Publication Number Publication Date
ATA800576A ATA800576A (de) 1978-03-15
AT346321B true AT346321B (de) 1978-11-10

Family

ID=24508491

Family Applications (1)

Application Number Title Priority Date Filing Date
AT800576A AT346321B (de) 1973-11-07 1976-10-28 Verfahren zur herstellung von neuen 4'- substituierten benzoylphenylnaphthalinen und den saeureadditionssalzen hievon

Country Status (30)

Country Link
JP (1) JPS6045191B2 (fr)
AR (1) AR214622A1 (fr)
AT (1) AT346321B (fr)
AU (1) AU509372B2 (fr)
BE (1) BE847716A (fr)
BG (1) BG27555A3 (fr)
CA (1) CA1078834A (fr)
CH (2) CH624398A5 (fr)
CS (1) CS235057B2 (fr)
DD (1) DD127460A5 (fr)
DE (1) DE2646213C2 (fr)
DK (1) DK484776A (fr)
ES (1) ES452735A1 (fr)
FR (1) FR2329264A1 (fr)
GB (1) GB1561687A (fr)
GR (1) GR61816B (fr)
HU (1) HU175227B (fr)
IE (1) IE43641B1 (fr)
IL (1) IL50772A (fr)
MX (1) MX4291E (fr)
NL (1) NL187164C (fr)
NZ (1) NZ182421A (fr)
PH (1) PH14538A (fr)
PL (2) PL111987B1 (fr)
PT (1) PT65752B (fr)
RO (1) RO70755A (fr)
SE (1) SE428689B (fr)
SU (2) SU791220A3 (fr)
YU (1) YU262276A (fr)
ZA (1) ZA766439B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179558A (en) * 1978-01-30 1979-12-18 E. R. Squibb & Sons, Inc. Naphthalenone derivatives and analogs
DE3121175A1 (de) * 1981-05-27 1982-12-16 Klinge Pharma GmbH, 8000 München Erythro-1,2,3-triphenyl-1-pentanon-derivate sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPH0717589B2 (ja) * 1990-01-22 1995-03-01 ファイザー製薬株式会社 新規１，３―ジカルボニル化合物およびその組成物
US6391892B1 (en) * 1995-03-10 2002-05-21 Eli Lilly And Company Naphthyl pharmaceutical compounds

Also Published As

Publication number Publication date
AU509372B2 (en) 1980-05-08
RO70755A (fr) 1981-01-30
DD127460A5 (fr) 1977-09-28
BG27555A3 (en) 1979-11-12
HU175227B (hu) 1980-06-28
JPS5253845A (en) 1977-04-30
CH624376A5 (en) 1981-07-31
GR61816B (en) 1979-01-22
ZA766439B (en) 1978-06-28
ES452735A1 (es) 1978-01-01
PT65752B (en) 1978-04-20
IE43641B1 (en) 1981-04-22
AR214622A1 (es) 1979-07-13
CH624398A5 (en) 1981-07-31
SU791220A3 (ru) 1980-12-23
DE2646213C2 (de) 1987-02-12
FR2329264B1 (fr) 1978-11-17
IE43641L (en) 1977-04-28
IL50772A0 (en) 1976-12-31
MX4291E (es) 1982-03-17
GB1561687A (en) 1980-02-27
PL104551B1 (pl) 1979-08-31
PL111987B1 (en) 1980-09-30
AU1900476A (en) 1978-05-04
JPS6045191B2 (ja) 1985-10-08
ATA800576A (de) 1978-03-15
FR2329264A1 (fr) 1977-05-27
DK484776A (da) 1977-04-29
YU262276A (en) 1982-05-31
PT65752A (en) 1976-11-01
IL50772A (en) 1980-11-30
CA1078834A (fr) 1980-06-03
NZ182421A (en) 1978-11-13
NL187164B (nl) 1991-01-16
NL7611974A (nl) 1977-05-02
SU818476A3 (ru) 1981-03-30
NL187164C (nl) 1991-06-17
BE847716A (fr) 1977-04-28
CS235057B2 (en) 1985-04-16
SE7611953L (sv) 1977-04-29
SE428689B (sv) 1983-07-18
PH14538A (en) 1981-09-24
DE2646213A1 (de) 1977-05-12

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