AT333770B - Verfahren zur herstellung von neuen bicyclischen imidazolen und pyrimidinen und ihren salzen - Google Patents

Verfahren zur herstellung von neuen bicyclischen imidazolen und pyrimidinen und ihren salzen

Info

Publication number
AT333770B
AT333770B AT1026573A AT1026573A AT333770B AT 333770 B AT333770 B AT 333770B AT 1026573 A AT1026573 A AT 1026573A AT 1026573 A AT1026573 A AT 1026573A AT 333770 B AT333770 B AT 333770B
Authority
AT
Austria
Prior art keywords
pyrimidines
salt
preparation
new bicyclic
imidazoles
Prior art date
Application number
AT1026573A
Other languages
English (en)
Other versions
ATA1026573A (de
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Priority to AT228676A priority Critical patent/AT356650B/de
Priority to AT228576A priority patent/AT356649B/de
Publication of ATA1026573A publication Critical patent/ATA1026573A/de
Application granted granted Critical
Publication of AT333770B publication Critical patent/AT333770B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/42Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/48Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12Nitrogen atoms not forming part of a nitro radical
    • C07D239/14Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT1026573A 1972-12-08 1973-12-07 Verfahren zur herstellung von neuen bicyclischen imidazolen und pyrimidinen und ihren salzen AT333770B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT228676A AT356650B (de) 1973-12-07 1973-12-07 Verfahren zur herstellung von neuen bicyc- lischen imidazol- und pyrimidinderivaten und ihren salzen
AT228576A AT356649B (de) 1972-12-08 1976-03-29 Verfahren zur herstellung von neuen bicyclischen imidazolderivaten und ihren salzen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US313285A US3865836A (en) 1972-12-08 1972-12-08 Bicyclic imidazoles

Publications (2)

Publication Number Publication Date
ATA1026573A ATA1026573A (de) 1976-04-15
AT333770B true AT333770B (de) 1976-12-10

Family

ID=23215116

Family Applications (1)

Application Number Title Priority Date Filing Date
AT1026573A AT333770B (de) 1972-12-08 1973-12-07 Verfahren zur herstellung von neuen bicyclischen imidazolen und pyrimidinen und ihren salzen

Country Status (23)

Country Link
US (1) US3865836A (de)
JP (1) JPS4994694A (de)
AT (1) AT333770B (de)
BE (1) BE808416A (de)
BG (1) BG21608A3 (de)
CA (1) CA1010864A (de)
CH (1) CH593975A5 (de)
DE (1) DE2361188A1 (de)
DK (1) DK141289B (de)
FI (1) FI54711C (de)
FR (1) FR2209576B1 (de)
GB (1) GB1446482A (de)
HU (1) HU168638B (de)
IE (1) IE38618B1 (de)
IL (1) IL43770A (de)
NL (1) NL7316778A (de)
NO (1) NO139087C (de)
PH (1) PH10417A (de)
PL (1) PL94683B1 (de)
RO (1) RO63263A (de)
SE (1) SE411627B (de)
SU (1) SU578003A3 (de)
ZA (1) ZA739343B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG25138A1 (en) * 1977-07-06 1978-08-10 Georgiev A method of obtaining of rs-(+/-)-2,3,5,6-tetrahydro-6-phenylimidazo-(2,1-b)-thiazol(tetramizol)
HU181927B (en) * 1977-07-06 1983-11-28 Iso Pharmachim Process for producing r,s-2,3,5,6-tetrahydro-6-phenyl-imidazo-bracket-2,1-b-bracket closed thiazol /tetramizol/
DE2827617A1 (de) * 1978-06-23 1980-01-10 Boehringer Sohn Ingelheim Neue imidazo eckige klammer auf 1,2- alpha eckige klammer zu imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
US4370500A (en) * 1978-11-06 1983-01-25 American Cyanamid Company Compound: d-N-(2-amino-2-phenethyl)-2-methoxyethylamine and process for preparing the same by selective crystallization
DE3042636A1 (de) * 1980-11-12 1982-06-16 C.H. Boehringer Sohn, 6507 Ingelheim Neue 7-(2,6-dibrom-4-methylphenyl)-2,3-dihydro-imidazo(1,2-a)imidazole, deren saeureadditionssalze, diese enhthaltende arzneimittel und verfahren zu deren herstellung
GB8509531D0 (en) * 1985-04-13 1985-05-15 Bp Chem Int Ltd Preparation of guanidines
US6359144B1 (en) * 1997-02-04 2002-03-19 Lion Bioscience Ag Combinatorial libraries of bicyclic guanidine derivatives and compounds therein
EE200300342A (et) * 2001-01-26 2003-12-15 Bristol-Myers Squibb Company Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine
NZ531244A (en) * 2001-09-21 2006-06-30 Sanofi Aventis Substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-A]pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo [1,2-A]pyrimidin-5(1H)one derivatives for neurodegenerative disorders
CA2610812A1 (en) * 2005-06-14 2006-12-28 Schering Corporation Aspartyl protease inhibitors
US8563560B2 (en) * 2011-02-25 2013-10-22 Ppg Industries Ohio, Inc. Preparation of bicyclic guanidine salts in an aqueous media

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB796996A (en) * 1956-03-29 1958-06-25 Monsanto Canada Ltd Imidazole derivatives
GB805877A (en) * 1957-01-28 1958-12-17 Monsanto Canada Ltd Process for the production of 2, 3, 5, 6-tetrahydro-1-imidaz (1, 2-a) imidazole

Also Published As

Publication number Publication date
IE38618B1 (en) 1978-04-26
SU578003A3 (ru) 1977-10-25
HU168638B (de) 1976-06-28
DK141289B (da) 1980-02-18
ATA1026573A (de) 1976-04-15
DK141289C (de) 1980-08-11
JPS4994694A (de) 1974-09-09
RO63263A (fr) 1978-08-15
BE808416A (fr) 1974-06-10
SE411627B (sv) 1980-01-21
NO139087C (no) 1979-01-03
IL43770A (en) 1976-08-31
US3865836A (en) 1975-02-11
ZA739343B (en) 1975-07-30
NO139087B (no) 1978-09-25
IL43770A0 (en) 1974-03-14
AU6337173A (en) 1975-06-12
PL94683B1 (pl) 1977-08-31
NL7316778A (de) 1974-06-11
IE38618L (en) 1974-06-08
FR2209576B1 (de) 1977-01-28
CA1010864A (en) 1977-05-24
FI54711B (fi) 1978-10-31
PH10417A (en) 1977-03-16
DE2361188A1 (de) 1974-06-12
FI54711C (fi) 1979-02-12
FR2209576A1 (de) 1974-07-05
GB1446482A (en) 1976-08-18
CH593975A5 (de) 1977-12-30
BG21608A3 (de) 1976-07-20

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee