NO139087C - Analogifremgangsmaater til fremstilling av terapeutisk aktive bicykliske imidazoler og pyrimidiner - Google Patents

Analogifremgangsmaater til fremstilling av terapeutisk aktive bicykliske imidazoler og pyrimidiner

Info

Publication number
NO139087C
NO139087C NO734672A NO467273A NO139087C NO 139087 C NO139087 C NO 139087C NO 734672 A NO734672 A NO 734672A NO 467273 A NO467273 A NO 467273A NO 139087 C NO139087 C NO 139087C
Authority
NO
Norway
Prior art keywords
analogical
pyrimidines
procedures
preparation
therapeutically active
Prior art date
Application number
NO734672A
Other languages
English (en)
Norwegian (no)
Other versions
NO139087B (no
Inventor
Josephus L H Van Gelder
Willy Joannes Van Laerhoven
Alfons Herman Marg Raeymaekers
Leopold Frans Corneel Roevens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO139087B publication Critical patent/NO139087B/no
Publication of NO139087C publication Critical patent/NO139087C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/42Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/48Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12Nitrogen atoms not forming part of a nitro radical
    • C07D239/14Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO734672A 1972-12-08 1973-12-06 Analogifremgangsmaater til fremstilling av terapeutisk aktive bicykliske imidazoler og pyrimidiner NO139087C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US313285A US3865836A (en) 1972-12-08 1972-12-08 Bicyclic imidazoles

Publications (2)

Publication Number Publication Date
NO139087B NO139087B (no) 1978-09-25
NO139087C true NO139087C (no) 1979-01-03

Family

ID=23215116

Family Applications (1)

Application Number Title Priority Date Filing Date
NO734672A NO139087C (no) 1972-12-08 1973-12-06 Analogifremgangsmaater til fremstilling av terapeutisk aktive bicykliske imidazoler og pyrimidiner

Country Status (23)

Country Link
US (1) US3865836A (de)
JP (1) JPS4994694A (de)
AT (1) AT333770B (de)
BE (1) BE808416A (de)
BG (1) BG21608A3 (de)
CA (1) CA1010864A (de)
CH (1) CH593975A5 (de)
DE (1) DE2361188A1 (de)
DK (1) DK141289B (de)
FI (1) FI54711C (de)
FR (1) FR2209576B1 (de)
GB (1) GB1446482A (de)
HU (1) HU168638B (de)
IE (1) IE38618B1 (de)
IL (1) IL43770A (de)
NL (1) NL7316778A (de)
NO (1) NO139087C (de)
PH (1) PH10417A (de)
PL (1) PL94683B1 (de)
RO (1) RO63263A (de)
SE (1) SE411627B (de)
SU (1) SU578003A3 (de)
ZA (1) ZA739343B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181927B (en) * 1977-07-06 1983-11-28 Iso Pharmachim Process for producing r,s-2,3,5,6-tetrahydro-6-phenyl-imidazo-bracket-2,1-b-bracket closed thiazol /tetramizol/
BG25138A1 (en) * 1977-07-06 1978-08-10 Georgiev A method of obtaining of rs-(+/-)-2,3,5,6-tetrahydro-6-phenylimidazo-(2,1-b)-thiazol(tetramizol)
DE2827617A1 (de) * 1978-06-23 1980-01-10 Boehringer Sohn Ingelheim Neue imidazo eckige klammer auf 1,2- alpha eckige klammer zu imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
US4370500A (en) * 1978-11-06 1983-01-25 American Cyanamid Company Compound: d-N-(2-amino-2-phenethyl)-2-methoxyethylamine and process for preparing the same by selective crystallization
DE3042636A1 (de) * 1980-11-12 1982-06-16 C.H. Boehringer Sohn, 6507 Ingelheim Neue 7-(2,6-dibrom-4-methylphenyl)-2,3-dihydro-imidazo(1,2-a)imidazole, deren saeureadditionssalze, diese enhthaltende arzneimittel und verfahren zu deren herstellung
GB8509531D0 (en) * 1985-04-13 1985-05-15 Bp Chem Int Ltd Preparation of guanidines
US6359144B1 (en) * 1997-02-04 2002-03-19 Lion Bioscience Ag Combinatorial libraries of bicyclic guanidine derivatives and compounds therein
IL156813A0 (en) * 2001-01-26 2004-02-08 Bristol Myers Squibb Co Imidazolyl derivatives and pharmaceutical compositions containing the same
IL160397A0 (en) * 2001-09-21 2004-07-25 Sanofi Synthelabo Substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido{1,2-a} pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo {1,2-a} pyrimidin-5 (1h) one derivatives for neurodegenerative disorders
MX2007016175A (es) * 2005-06-14 2008-03-07 Schering Corp Inhibidor de aspartil proteasas.
US8563560B2 (en) * 2011-02-25 2013-10-22 Ppg Industries Ohio, Inc. Preparation of bicyclic guanidine salts in an aqueous media

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB796996A (en) * 1956-03-29 1958-06-25 Monsanto Canada Ltd Imidazole derivatives
GB805877A (en) * 1957-01-28 1958-12-17 Monsanto Canada Ltd Process for the production of 2, 3, 5, 6-tetrahydro-1-imidaz (1, 2-a) imidazole

Also Published As

Publication number Publication date
AU6337173A (en) 1975-06-12
FI54711B (fi) 1978-10-31
IL43770A (en) 1976-08-31
US3865836A (en) 1975-02-11
DK141289B (da) 1980-02-18
RO63263A (fr) 1978-08-15
BE808416A (fr) 1974-06-10
NL7316778A (de) 1974-06-11
JPS4994694A (de) 1974-09-09
CA1010864A (en) 1977-05-24
DK141289C (de) 1980-08-11
SE411627B (sv) 1980-01-21
SU578003A3 (ru) 1977-10-25
PH10417A (en) 1977-03-16
IL43770A0 (en) 1974-03-14
FR2209576B1 (de) 1977-01-28
FI54711C (fi) 1979-02-12
DE2361188A1 (de) 1974-06-12
FR2209576A1 (de) 1974-07-05
GB1446482A (en) 1976-08-18
ATA1026573A (de) 1976-04-15
ZA739343B (en) 1975-07-30
HU168638B (de) 1976-06-28
PL94683B1 (pl) 1977-08-31
IE38618B1 (en) 1978-04-26
NO139087B (no) 1978-09-25
IE38618L (en) 1974-06-08
AT333770B (de) 1976-12-10
CH593975A5 (de) 1977-12-30
BG21608A3 (de) 1976-07-20

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