FI54711B - Foerfarande foer framstaellning av terapeutiskt anvaendbara bicykliska imidazoler och pyrimidiner - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara bicykliska imidazoler och pyrimidiner

Info

Publication number
FI54711B
FI54711B FI3729/73A FI372973A FI54711B FI 54711 B FI54711 B FI 54711B FI 3729/73 A FI3729/73 A FI 3729/73A FI 372973 A FI372973 A FI 372973A FI 54711 B FI54711 B FI 54711B
Authority
FI
Finland
Prior art keywords
pyrimidiner
imidazoler
bicyclic
procedure
processing
Prior art date
Application number
FI3729/73A
Other languages
English (en)
Other versions
FI54711C (fi
Inventor
Josephus Ludovicus Hube Gelder
Willy Joannes Van Laerhoven
Alfons Herman Marg Raeymaekers
Leopold Frans Corneel Roevens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of FI54711B publication Critical patent/FI54711B/fi
Publication of FI54711C publication Critical patent/FI54711C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/42Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/48Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12Nitrogen atoms not forming part of a nitro radical
    • C07D239/14Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms
FI3729/73A 1972-12-08 1973-12-05 Foerfarande foer framstaellning av terapeutiskt anvaendbara bicykliska imidazoler och pyrimidiner FI54711C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US313285A US3865836A (en) 1972-12-08 1972-12-08 Bicyclic imidazoles

Publications (2)

Publication Number Publication Date
FI54711B true FI54711B (fi) 1978-10-31
FI54711C FI54711C (fi) 1979-02-12

Family

ID=23215116

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3729/73A FI54711C (fi) 1972-12-08 1973-12-05 Foerfarande foer framstaellning av terapeutiskt anvaendbara bicykliska imidazoler och pyrimidiner

Country Status (23)

Country Link
US (1) US3865836A (fi)
JP (1) JPS4994694A (fi)
AT (1) AT333770B (fi)
BE (1) BE808416A (fi)
BG (1) BG21608A3 (fi)
CA (1) CA1010864A (fi)
CH (1) CH593975A5 (fi)
DE (1) DE2361188A1 (fi)
DK (1) DK141289B (fi)
FI (1) FI54711C (fi)
FR (1) FR2209576B1 (fi)
GB (1) GB1446482A (fi)
HU (1) HU168638B (fi)
IE (1) IE38618B1 (fi)
IL (1) IL43770A (fi)
NL (1) NL7316778A (fi)
NO (1) NO139087C (fi)
PH (1) PH10417A (fi)
PL (1) PL94683B1 (fi)
RO (1) RO63263A (fi)
SE (1) SE411627B (fi)
SU (1) SU578003A3 (fi)
ZA (1) ZA739343B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG25138A1 (en) * 1977-07-06 1978-08-10 Georgiev A method of obtaining of rs-(+/-)-2,3,5,6-tetrahydro-6-phenylimidazo-(2,1-b)-thiazol(tetramizol)
HU181927B (en) * 1977-07-06 1983-11-28 Iso Pharmachim Process for producing r,s-2,3,5,6-tetrahydro-6-phenyl-imidazo-bracket-2,1-b-bracket closed thiazol /tetramizol/
DE2827617A1 (de) * 1978-06-23 1980-01-10 Boehringer Sohn Ingelheim Neue imidazo eckige klammer auf 1,2- alpha eckige klammer zu imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
US4370500A (en) * 1978-11-06 1983-01-25 American Cyanamid Company Compound: d-N-(2-amino-2-phenethyl)-2-methoxyethylamine and process for preparing the same by selective crystallization
DE3042636A1 (de) * 1980-11-12 1982-06-16 C.H. Boehringer Sohn, 6507 Ingelheim Neue 7-(2,6-dibrom-4-methylphenyl)-2,3-dihydro-imidazo(1,2-a)imidazole, deren saeureadditionssalze, diese enhthaltende arzneimittel und verfahren zu deren herstellung
GB8509531D0 (en) * 1985-04-13 1985-05-15 Bp Chem Int Ltd Preparation of guanidines
US6359144B1 (en) * 1997-02-04 2002-03-19 Lion Bioscience Ag Combinatorial libraries of bicyclic guanidine derivatives and compounds therein
EP1359916A4 (en) * 2001-01-26 2004-04-07 Bristol Myers Squibb Co IMIDAZOLYLATED DERIVATIVES AS INHIBITORS OF CORTICOTROPIN RELEASE FACTOR
EP1430056B1 (en) * 2001-09-21 2005-10-26 Sanofi-Aventis Substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h)one derivatives for neurodegenerative disorders
ATE482214T1 (de) * 2005-06-14 2010-10-15 Schering Corp Aspartylproteasehemmer
US8563560B2 (en) * 2011-02-25 2013-10-22 Ppg Industries Ohio, Inc. Preparation of bicyclic guanidine salts in an aqueous media

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB796996A (en) * 1956-03-29 1958-06-25 Monsanto Canada Ltd Imidazole derivatives
GB805877A (en) * 1957-01-28 1958-12-17 Monsanto Canada Ltd Process for the production of 2, 3, 5, 6-tetrahydro-1-imidaz (1, 2-a) imidazole

Also Published As

Publication number Publication date
NO139087B (no) 1978-09-25
DK141289B (da) 1980-02-18
DE2361188A1 (de) 1974-06-12
AU6337173A (en) 1975-06-12
IE38618L (en) 1974-06-08
FI54711C (fi) 1979-02-12
DK141289C (fi) 1980-08-11
NO139087C (no) 1979-01-03
JPS4994694A (fi) 1974-09-09
BG21608A3 (fi) 1976-07-20
PH10417A (en) 1977-03-16
PL94683B1 (pl) 1977-08-31
SE411627B (sv) 1980-01-21
AT333770B (de) 1976-12-10
CH593975A5 (fi) 1977-12-30
BE808416A (fr) 1974-06-10
NL7316778A (fi) 1974-06-11
IL43770A (en) 1976-08-31
US3865836A (en) 1975-02-11
HU168638B (fi) 1976-06-28
FR2209576B1 (fi) 1977-01-28
ZA739343B (en) 1975-07-30
IE38618B1 (en) 1978-04-26
IL43770A0 (en) 1974-03-14
ATA1026573A (de) 1976-04-15
CA1010864A (en) 1977-05-24
SU578003A3 (ru) 1977-10-25
RO63263A (fr) 1978-08-15
FR2209576A1 (fi) 1974-07-05
GB1446482A (en) 1976-08-18

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