AT332399B - Verfahren zur herstellung von butyrophenonverbindungen - Google Patents
Verfahren zur herstellung von butyrophenonverbindungenInfo
- Publication number
- AT332399B AT332399B AT233973A AT233973A AT332399B AT 332399 B AT332399 B AT 332399B AT 233973 A AT233973 A AT 233973A AT 233973 A AT233973 A AT 233973A AT 332399 B AT332399 B AT 332399B
- Authority
- AT
- Austria
- Prior art keywords
- producing
- butyrophenone compounds
- butyrophenone
- compounds
- producing butyrophenone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/16—Radicals substituted by halogen atoms or nitro radicals
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT18775*#A AT334372B (de) | 1972-06-07 | 1975-01-13 | Verfahren zur herstellung von neuen difluorbutyrophenonverbindungen und ihren saureadditionssalzen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP47027610A JPS5755714B2 (de) | 1972-03-18 | 1972-03-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA233973A ATA233973A (de) | 1976-01-15 |
AT332399B true AT332399B (de) | 1976-09-27 |
Family
ID=12225684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT233973A AT332399B (de) | 1972-03-18 | 1973-03-16 | Verfahren zur herstellung von butyrophenonverbindungen |
Country Status (7)
Country | Link |
---|---|
US (1) | US3979390A (de) |
JP (1) | JPS5755714B2 (de) |
AT (1) | AT332399B (de) |
BE (1) | BE796893A (de) |
CS (1) | CS174873B2 (de) |
DE (1) | DE2313258A1 (de) |
SU (1) | SU568361A3 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5922703B2 (ja) * | 1975-07-18 | 1984-05-28 | 住友化学工業株式会社 | オルト−アミノブチロフエノン誘導体の新規な製造法 |
JPS595587B2 (ja) * | 1974-04-18 | 1984-02-06 | 住友化学工業株式会社 | シンキナブチロフエノンユウドウタイ オヨビ ソノエン ノ セイホウ |
FI60390C (fi) * | 1975-03-05 | 1982-01-11 | Sumitomo Chemical Co | Foerfarande foer framstaellning av neuroleptiska butyrofenoner |
US4160836A (en) * | 1976-05-17 | 1979-07-10 | Janssen Pharmaceutica N.V. | Antiemetic 1-(benzothiazolylalkyl)piperidine derivatives |
US4116963A (en) * | 1977-05-23 | 1978-09-26 | G.D. Searle & Co. | 3,3,3-triarylalkyl-4-phenylalkyl-4-hydroxy piperidines and related compounds |
US4216325A (en) * | 1978-07-11 | 1980-08-05 | A. H. Robins Company, Inc. | 4-(p-Fluorobenzoyl)-1-[3-(p-fluorobenzoyl)propyl]piperidine |
JPS57212180A (en) * | 1981-06-19 | 1982-12-27 | Yoshitomi Pharmaceut Ind Ltd | Tetrahydrofuran(thiophene) compound |
EP0187162B1 (de) * | 1984-05-22 | 1989-11-02 | Sumitomo Chemical Company, Limited | Radioaktives iodospiroperidol und herstellung |
JPS6248684A (ja) * | 1985-08-26 | 1987-03-03 | Sumitomo Chem Co Ltd | 新規なヨ−ドブチロフエノン誘導体およびその製造法 |
JPH085882B2 (ja) * | 1986-12-26 | 1996-01-24 | 住友化学工業株式会社 | 新規なヨ−ドスピロペリド−ル誘導体およびその製造法 |
DE19952146A1 (de) * | 1999-10-29 | 2001-06-07 | Boehringer Ingelheim Pharma | Arylalkane, Arylalkene und Aryl-azaalkane, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
BR0307624A (pt) | 2002-03-13 | 2005-01-11 | Janssen Pharmaceutica Nv | Inibidores de histona desacetilase |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB948071A (en) * | 1959-05-01 | 1964-01-29 | May & Baker Ltd | New heterocyclic compounds |
GB895309A (en) * | 1959-11-18 | 1962-05-02 | Res Lab Dr C Janssen Nv | Pyrrolidine and piperidine derivatives |
US3155669A (en) * | 1962-06-22 | 1964-11-03 | Res Lab Dr C Janssen N V | 2, 4, 8-triaza-spiro (4, 5) dec-2-enes |
US3161645A (en) * | 1962-12-18 | 1964-12-15 | Res Lab Dr C Janssen N V | 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds |
GB1141664A (en) * | 1965-12-08 | 1969-01-29 | Janssen Pharmaceutica Nv | Piperidine derivatives |
US3476762A (en) * | 1966-12-27 | 1969-11-04 | Aldrich Chem Co Inc | 4' - dimethylamino - 4 - (4 - hydroxy-4-phenyl piperidino)butyrophenones and 4 - (4-phenyl-4-hydroxy - piperidino)-1,1-ethylenedioxy - 1 - (4 - dimethylaminophenyl)butanes |
FI52216C (fi) * | 1969-07-16 | 1977-07-11 | Sumitomo Chemical Co | Menetelmä gamma-piperidinobutyrofenonijohdannaisten valmistamiseksi. |
DE2110534C3 (de) * | 1970-03-06 | 1979-03-08 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | γ-Piperazinobutyrophenonderivate, Verfahren zu ihrer Herstellung und Arzneipräparate |
US3799932A (en) * | 1970-03-20 | 1974-03-26 | Sumitomo Chemical Co | Gamma-piperidinobutyrophenones |
-
1972
- 1972-03-18 JP JP47027610A patent/JPS5755714B2/ja not_active Expired
-
1973
- 1973-03-15 CS CS1876A patent/CS174873B2/cs unknown
- 1973-03-16 AT AT233973A patent/AT332399B/de not_active IP Right Cessation
- 1973-03-16 DE DE2313258A patent/DE2313258A1/de not_active Ceased
- 1973-03-16 BE BE128894A patent/BE796893A/xx unknown
- 1973-03-16 SU SU7301896462A patent/SU568361A3/ru active
- 1973-03-16 US US05/341,858 patent/US3979390A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATA233973A (de) | 1976-01-15 |
SU568361A3 (ru) | 1977-08-05 |
BE796893A (fr) | 1973-09-17 |
CS174873B2 (de) | 1977-04-29 |
JPS4892378A (de) | 1973-11-30 |
JPS5755714B2 (de) | 1982-11-25 |
US3979390A (en) | 1976-09-07 |
DE2313258A1 (de) | 1973-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee |