AT327203B - Verfahren zur herstellung von neuen n,n'-disubstituierten cyclischen diaminen und deren saureadditionssalzen - Google Patents

Verfahren zur herstellung von neuen n,n'-disubstituierten cyclischen diaminen und deren saureadditionssalzen

Info

Publication number
AT327203B
AT327203B AT981272A AT981272A AT327203B AT 327203 B AT327203 B AT 327203B AT 981272 A AT981272 A AT 981272A AT 981272 A AT981272 A AT 981272A AT 327203 B AT327203 B AT 327203B
Authority
AT
Austria
Prior art keywords
preparation
new
acid addition
addition salts
cyclic diamines
Prior art date
Application number
AT981272A
Other languages
German (de)
English (en)
Other versions
ATA981272A (de
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Priority to AT469774*7A priority Critical patent/AT327207B/de
Priority to AT469674A priority patent/AT336625B/de
Publication of ATA981272A publication Critical patent/ATA981272A/de
Application granted granted Critical
Publication of AT327203B publication Critical patent/AT327203B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT981272A 1971-11-19 1972-11-17 Verfahren zur herstellung von neuen n,n'-disubstituierten cyclischen diaminen und deren saureadditionssalzen AT327203B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT469774*7A AT327207B (de) 1971-11-19 1972-11-17 Verfahren zur herstellung von neuen n,n'-disubstituierten cyclischen diaminen und deren saureadditionssalzen
AT469674A AT336625B (de) 1971-11-19 1974-11-17 Verfahren zur herstellung von neuen n,n'-disubstituierten cyclischen diaminen und deren saureadditionssalzen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2157424A DE2157424C3 (de) 1971-11-19 1971-11-19 Therapeutisch wirksame N5N'disubstituierte cyclische Diamine und Verfahren zu deren Herstellung
DE2240665A DE2240665C2 (de) 1971-11-19 1972-08-18 N,N'disubstituierte cyclische Diamine

Publications (2)

Publication Number Publication Date
ATA981272A ATA981272A (de) 1975-04-15
AT327203B true AT327203B (de) 1976-01-26

Family

ID=25762040

Family Applications (1)

Application Number Title Priority Date Filing Date
AT981272A AT327203B (de) 1971-11-19 1972-11-17 Verfahren zur herstellung von neuen n,n'-disubstituierten cyclischen diaminen und deren saureadditionssalzen

Country Status (12)

Country Link
US (1) US4374990A (forum.php)
JP (4) JPS5523831B2 (forum.php)
AT (1) AT327203B (forum.php)
BE (1) BE791501A (forum.php)
CA (1) CA1025866A (forum.php)
CH (4) CH613202A5 (forum.php)
DE (2) DE2157424C3 (forum.php)
ES (1) ES408565A1 (forum.php)
FR (1) FR2160611B1 (forum.php)
GB (1) GB1407854A (forum.php)
NL (1) NL170147C (forum.php)
SE (1) SE408423B (forum.php)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791501A (fr) * 1971-11-19 1973-05-17 Albert Ag Chem Werke Diamines cycliques n,n'-disubstituees et leur procede de preparation
GB1382602A (en) * 1972-06-01 1975-02-05 Labaz Benzodioxan compounds and process for preparing the same
AR207031A1 (es) * 1974-03-06 1976-09-09 Kyorin Seiyaku Kk Procedimiento para preparacion de nuevos derivados de 1-(3-fenilpropil)-4-furoilpiperacina
DE2757532A1 (de) * 1977-12-23 1979-07-05 Hoechst Ag N,n'-disubstituiertes cyclisches diamin und verfahren zu dessen herstellung
US4593102A (en) * 1984-04-10 1986-06-03 A. H. Robins Company, Inc. N-[(amino)alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulfur linked substitution in the 2, 3 or 4-position
IT1176613B (it) * 1984-08-14 1987-08-18 Ravizza Spa Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione
DE3669876D1 (de) * 1985-05-13 1990-05-03 Kuraray Co 3,4-dihydrobenzopyranderivate.
DE3529994A1 (de) * 1985-08-22 1987-02-26 Hoechst Ag Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
JP2573195B2 (ja) * 1986-09-30 1997-01-22 エーザイ株式会社 環状アミン誘導体
US4937246A (en) * 1987-11-25 1990-06-26 Takeda Chemical Industries, Ltd. PAF antagonist, 1,4-disubstituted piperazine compounds and production thereof
JPH01217875A (ja) * 1988-02-24 1989-08-31 Matsushita Electric Works Ltd 配線ダクト用プラグ
US4997836A (en) * 1988-11-11 1991-03-05 Takeda Chemical Industries, Ltd. Trisubstituted piperazine compounds, their production and use
EP0385043A1 (en) * 1989-02-28 1990-09-05 Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. (Faes) New derivatives of 4-substituted piperazines
US5739132A (en) * 1992-07-02 1998-04-14 Tanabe Seiyaku Co., Ltd. Pyridazinone derivatives and processes for preparing the same
SE9202266D0 (sv) * 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel piperazine carboxamides
DE4332384A1 (de) * 1993-09-23 1995-03-30 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten III
FR2724656B1 (fr) * 1994-09-15 1996-12-13 Adir Nouveaux derives du benzopyranne, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6395738B1 (en) * 1997-10-01 2002-05-28 Kyowa Hakko Kogyo Co., Ltd. Benzofuran derivatives
AUPP818099A0 (en) 1999-01-14 1999-02-11 Fujisawa Pharmaceutical Co., Ltd. New n-containing heterocyclic compounds
US6541477B2 (en) * 1999-08-27 2003-04-01 Scios, Inc. Inhibitors of p38-a kinase
EP1257544B1 (en) * 2000-02-11 2012-07-25 Vertex Pharmaceuticals Incorporated Piperazine and piperidine derivatives for treatment or prevention of neuronal damage
DE10035908A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
CA2440438C (en) * 2001-03-09 2011-05-03 Ortho-Mcneil Pharmaceutical, Inc. Heterocyclic compounds
CN1703401A (zh) 2001-05-22 2005-11-30 神经原公司 黑色素浓集激素受体的配体:取代的1－苄基－4－芳基哌嗪类似物
US20040204477A1 (en) * 2001-07-09 2004-10-14 Juergen Moll Interaction inhibitors of tcf-4 with beta-catenin
US7037913B2 (en) * 2002-05-01 2006-05-02 Bristol-Myers Squibb Company Bicyclo 4.4.0 antiviral derivatives
WO2003101871A1 (fr) * 2002-06-04 2003-12-11 Canon Kabushiki Kaisha Procede de detection d'alimentation en double de feuilles et dispositif servant a detecter l'alimentation en double de feuilles
BR0312294A (pt) * 2002-06-29 2005-04-12 Zentaris Gmbh Arilcarbonil piperazinas e hteroarilcarbonilpiperazinas e o uso das mesmas para tratamento de doenças benignas e malignas
US20040034019A1 (en) * 2002-08-08 2004-02-19 Ronald Tomlinson Piperazine and piperidine derivatives
KR20050033662A (ko) 2002-09-06 2005-04-12 얀센 파마슈티카 엔.브이. 헤테로사이클릭 화합물
US20040127395A1 (en) * 2002-09-06 2004-07-01 Desai Pragnya J. Use of histamine H4 receptor modulators for the treatment of allergy and asthma
SE0400441D0 (sv) * 2004-02-25 2004-02-25 Active Biotech Ab Novel Benzofurans and Indols
US20090018118A1 (en) * 2005-12-29 2009-01-15 Uros Urleb Heterocyclic compounds

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3037981A (en) * 1959-03-23 1962-06-05 Miles Lab Phenyltetrahydropyranylpiperazines
FR1369991A (fr) * 1963-04-05 1964-08-21 Lipha Nouvelles carboxamides-3 hydroxy-4 coumarines et leurs procédés de préparation
US3291798A (en) * 1964-02-25 1966-12-13 Upjohn Co Hydroquinones, lower alkanoyl derivatives thereof and processes for their production
DE1545786A1 (de) * 1965-01-27 1969-12-11 Hoechst Ag Verfahren zur Herstellung von Carbonsaeure-N-methylpiperaziden
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
US3472856A (en) * 1967-05-29 1969-10-14 Sterling Drug Inc 1-((thianaphthenyl)-lower-alkyl)-4-substituted-piperazines
US3637705A (en) * 1968-10-01 1972-01-25 Abbott Lab N-3 4-dihalo phenyl piperazines
US3646047A (en) * 1970-02-02 1972-02-29 American Cyanamid Co Certain benzo(b)thiophene-2-carboxamide derivatives
BE791501A (fr) * 1971-11-19 1973-05-17 Albert Ag Chem Werke Diamines cycliques n,n'-disubstituees et leur procede de preparation
US4115569A (en) * 1971-11-19 1978-09-19 Hoechst Aktiengesellschaft Cyclic diamine derivatives
US3865828A (en) * 1972-03-22 1975-02-11 Egyt Gyogyszervegyeszeti Gyar Pyridine derivatives having antidepressant activity
GB1428186A (en) * 1972-06-21 1976-03-17 Fujisawa Pharmaceutical Co Chromone derivatives
AR207031A1 (es) * 1974-03-06 1976-09-09 Kyorin Seiyaku Kk Procedimiento para preparacion de nuevos derivados de 1-(3-fenilpropil)-4-furoilpiperacina
DE2555290A1 (de) * 1975-12-09 1977-06-16 Boehringer Mannheim Gmbh Neue benzopyron-derivate und verfahren zu ihrer herstellung
US4123529A (en) * 1976-04-23 1978-10-31 Lilly Industries Limited Phenylpiperazine derivatives
DE2757532A1 (de) * 1977-12-23 1979-07-05 Hoechst Ag N,n'-disubstituiertes cyclisches diamin und verfahren zu dessen herstellung
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.

Also Published As

Publication number Publication date
DE2157424C3 (de) 1980-09-25
CH613202A5 (forum.php) 1979-09-14
JPS5253871A (en) 1977-04-30
ATA981272A (de) 1975-04-15
CH612430A5 (forum.php) 1979-07-31
CA1025866A (en) 1978-02-07
DE2240665A1 (de) 1974-03-07
ES408565A1 (es) 1975-11-01
JPS5523831B2 (forum.php) 1980-06-25
GB1407854A (en) 1975-09-24
SE408423B (sv) 1979-06-11
DE2240665C2 (de) 1982-07-08
JPS5760350B2 (forum.php) 1982-12-18
NL170147C (nl) 1982-10-01
JPS5519219B2 (forum.php) 1980-05-24
JPS5253872A (en) 1977-04-30
FR2160611A1 (forum.php) 1973-06-29
US4374990A (en) 1983-02-22
DE2157424A1 (de) 1973-05-24
CH592080A5 (forum.php) 1977-10-14
NL170147B (nl) 1982-05-03
JPS4861484A (forum.php) 1973-08-28
CH590265A5 (forum.php) 1977-07-29
JPS5440555B2 (forum.php) 1979-12-04
BE791501A (fr) 1973-05-17
NL7215416A (forum.php) 1973-05-22
DE2157424B2 (de) 1980-01-31
JPS5253873A (en) 1977-04-30
FR2160611B1 (forum.php) 1975-11-28

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