AT306930B - Verfahren zur Herstellung von 1-Glykosyl-5-azacytosinen - Google Patents

Verfahren zur Herstellung von 1-Glykosyl-5-azacytosinen

Info

Publication number
AT306930B
AT306930B AT439269A AT439269A AT306930B AT 306930 B AT306930 B AT 306930B AT 439269 A AT439269 A AT 439269A AT 439269 A AT439269 A AT 439269A AT 306930 B AT306930 B AT 306930B
Authority
AT
Austria
Prior art keywords
azacytosines
glycosyl
preparation
Prior art date
Application number
AT439269A
Other languages
German (de)
English (en)
Inventor
Alois Piskala
Frantisek Sorm
Original Assignee
Ceskoslovenska Akademie Ved
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceskoslovenska Akademie Ved filed Critical Ceskoslovenska Akademie Ved
Application granted granted Critical
Publication of AT306930B publication Critical patent/AT306930B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT439269A 1968-05-08 1969-05-07 Verfahren zur Herstellung von 1-Glykosyl-5-azacytosinen AT306930B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS339968 1968-05-08

Publications (1)

Publication Number Publication Date
AT306930B true AT306930B (de) 1973-04-25

Family

ID=5373920

Family Applications (1)

Application Number Title Priority Date Filing Date
AT439269A AT306930B (de) 1968-05-08 1969-05-07 Verfahren zur Herstellung von 1-Glykosyl-5-azacytosinen

Country Status (12)

Country Link
JP (1) JPS4916435B1 (enExample)
AT (1) AT306930B (enExample)
BE (1) BE732268A (enExample)
BR (1) BR6908600D0 (enExample)
CA (1) CA921904A (enExample)
CH (1) CH527207A (enExample)
DE (1) DE1922702A1 (enExample)
ES (1) ES366910A1 (enExample)
FR (1) FR2008048A1 (enExample)
GB (1) GB1227691A (enExample)
IT (1) IT1037009B (enExample)
NL (1) NL6906909A (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2012888C3 (de) * 1970-03-14 1981-04-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden
US6905669B2 (en) 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
US6982253B2 (en) 2002-06-05 2006-01-03 Supergen, Inc. Liquid formulation of decitabine and use of the same
US6943249B2 (en) 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US7038038B2 (en) 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
US20060014949A1 (en) * 2004-07-13 2006-01-19 Supergen Inc. Compositions and formulations of decitabine polymorphs and methods of use thereof
US7250416B2 (en) 2005-03-11 2007-07-31 Supergen, Inc. Azacytosine analogs and derivatives
US7700567B2 (en) 2005-09-29 2010-04-20 Supergen, Inc. Oligonucleotide analogues incorporating 5-aza-cytosine therein
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
HUE055911T2 (hu) 2008-05-15 2021-12-28 Celgene Corp Citidin-analógokat tartalmazó orális készítmények, és eljárások azok alkalmazására
EP2318423B1 (en) 2008-08-08 2014-05-07 ScinoPharm Taiwan, Ltd. Process for making 5-azacytosine nucleosides and their derivatives
AU2012236476A1 (en) 2011-03-31 2013-05-02 Celgene International Sarl Systhesis of 5-azacytidine
HUE042327T2 (hu) 2011-08-30 2019-06-28 Astex Pharmaceuticals Inc Decitabin-származék készítmények
HK1254645A1 (zh) 2015-07-02 2019-07-26 Otsuka Pharmaceutical Co., Ltd. 冻乾药物组合物
WO2017090264A1 (ja) 2015-11-27 2017-06-01 大原薬品工業株式会社 ５－アザシチジン又は其の２'－デオキシ体の５'位ジベンジル燐酸エステル
US10227374B2 (en) 2016-04-21 2019-03-12 Ohara Pharmaceutical Co., Ltd. Silyl etherified derivatives of 5-azacytidines in carbohydrate moiety
JP6162349B1 (ja) 2016-04-21 2017-07-12 大原薬品工業株式会社 ５−アザシチジン類の糖部シリルエーテル誘導体
WO2017183215A1 (ja) 2016-04-21 2017-10-26 大原薬品工業株式会社 ５－アザシチジン類の糖部シリルエーテル誘導体
SG11202000932XA (en) 2017-08-03 2020-02-27 Otsuka Pharma Co Ltd Drug compound and purification methods thereof
US20220332737A1 (en) * 2019-06-07 2022-10-20 Ludwig-Maximilians-Universität München Carbocyclic nucleoside analogue

Also Published As

Publication number Publication date
CA921904A (en) 1973-02-27
GB1227691A (enExample) 1971-04-07
CH527207A (de) 1972-08-31
BE732268A (enExample) 1969-10-01
BR6908600D0 (pt) 1973-02-22
ES366910A1 (es) 1971-03-16
DE1922702A1 (de) 1969-11-20
IT1037009B (it) 1979-11-10
FR2008048A1 (enExample) 1970-01-16
NL6906909A (enExample) 1969-11-11
JPS4916435B1 (enExample) 1974-04-22

Similar Documents

Publication Publication Date Title
CH507249A (de) Verfahren zur Herstellung von 2-Brom-a-ergokryptin
AT306930B (de) Verfahren zur Herstellung von 1-Glykosyl-5-azacytosinen
AT291254B (de) Verfahren zur herstellung von 3-amino-4jod-5-methyllisoxazolen
CH519453A (de) Verfahren zur Herstellung von Dihalogenphenolen
AT296964B (de) Verfahren zur Herstellung von 1-Hydroxyphenyl-2-aminoäthanolen
AT289084B (de) Verfahren zur Herstellung von Trimethyl-p-benzochinon
AT295757B (de) Verfahren zur Herstellung von Benzindenen
AT294064B (de) Verfahren zur Herstellung von 1-Alkyl-2-aminomethylpyrrolidinen
AT296254B (de) Verfahren zur Herstellung von 2-Acyloxythionobenzamiden
CH486444A (de) Verfahren zur Herstellung von 7-Cyan-cumarinen
CH519509A (de) Verfahren zur Herstellung von Thiophen-3-isonitrilen
CH511851A (de) Verfahren zur Herstellung von 2-Oxychinolinen
AT292205B (de) Verfahren zur Herstellung von 1-Peracylglykosyl-5-azacytosinen
AT286252B (de) Verfahren zur Herstellung von 3-Aminopropanolen
CH517081A (de) Verfahren zur Herstellung von a-Oximinoketonen
AT289737B (de) Verfahren zur Herstellung von Sulfatobetainen
CH517703A (de) Verfahren zur Herstellung von Glycyl-L-tryptophyl-L-methionyl-glycinamiden
CH505089A (de) Verfahren zur Herstellung von 3-substituierten-7-Aminocumarinen
AT296251B (de) Verfahren zur Herstellung von Methylcyclohexenen
CH518290A (de) Verfahren zur Herstellung von Hydroxyphenazin-di-N-oxiden
AT291577B (de) Verfahren zur Herstellung von Polyacyloxamidrazonen
CH484975A (de) Verfahren zur Herstellung von Polyacyloxamidrazonen
CH487927A (de) Verfahren zur Herstellung von 7-Triazolyl-cumarinen
CH508631A (de) Verfahren zur Herstellung von 2-Alkyl-4-nitroimidazolen
CH514524A (de) Verfahren zur Herstellung von Cyclopent-2-enyl-phenolen

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee