AT303015B - Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze - Google Patents

Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze

Info

Publication number
AT303015B
AT303015B AT784271A AT784271A AT303015B AT 303015 B AT303015 B AT 303015B AT 784271 A AT784271 A AT 784271A AT 784271 A AT784271 A AT 784271A AT 303015 B AT303015 B AT 303015B
Authority
AT
Austria
Prior art keywords
amides
esters
salts
new
production
Prior art date
Application number
AT784271A
Other languages
German (de)
English (en)
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2990769A external-priority patent/JPS5010299B1/ja
Priority claimed from JP2990569A external-priority patent/JPS5010298B1/ja
Priority claimed from JP8004269A external-priority patent/JPS5010308B1/ja
Priority claimed from JP10419469A external-priority patent/JPS4939995B1/ja
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Priority claimed from US00206966A external-priority patent/US3821404A/en
Application granted granted Critical
Publication of AT303015B publication Critical patent/AT303015B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT784271A 1969-04-16 1970-04-15 Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze AT303015B (de)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP2990769A JPS5010299B1 (enExample) 1969-04-16 1969-04-16
JP2990569A JPS5010298B1 (enExample) 1969-04-16 1969-04-16
JP3416669 1969-05-02
JP3416769 1969-05-02
JP8004169 1969-10-03
JP8004269A JPS5010308B1 (enExample) 1969-10-03 1969-10-03
JP10280969 1969-12-19
JP10419469A JPS4939995B1 (enExample) 1969-12-23 1969-12-23
US2641270A 1970-04-07 1970-04-07
US00206966A US3821404A (en) 1969-04-16 1971-12-10 Phenoxy carboxylic acid derivatives as anti-atherosclerosis agents

Publications (1)

Publication Number Publication Date
AT303015B true AT303015B (de) 1972-11-10

Family

ID=27579824

Family Applications (2)

Application Number Title Priority Date Filing Date
AT784271A AT303015B (de) 1969-04-16 1970-04-15 Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze
AT344070A AT302278B (de) 1969-04-16 1970-04-15 Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT344070A AT302278B (de) 1969-04-16 1970-04-15 Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze

Country Status (9)

Country Link
US (2) US3716583A (enExample)
AT (2) AT303015B (enExample)
BE (1) BE748970A (enExample)
CA (1) CA964273A (enExample)
CH (2) CH539012A (enExample)
DK (1) DK128731B (enExample)
FI (1) FI52570C (enExample)
FR (1) FR2042333B1 (enExample)
NL (1) NL139016B (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
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US4008265A (en) * 1971-05-22 1977-02-15 Sumitomo Chemical Company, Limited Novel bisphenoxy carboxylic acid derivatives and their salts
US4092324A (en) * 1971-05-22 1978-05-30 Sumitomo Chemical Company, Limited Diheterocyclic esters of 4-(1,1-bis-(phenoxy-propionic or -butoyric acid)-cyclohexane)α-methyl substituted
JPS575214B2 (enExample) * 1972-06-01 1982-01-29
JPS4931651A (enExample) * 1972-07-20 1974-03-22
JPS5735171B2 (enExample) * 1973-07-02 1982-07-27
AT353776B (de) * 1973-12-27 1979-12-10 Siegfried Ag Verfahren zur herstellung von neuen alkan- saeuren, deren estern und salzen
CH617417A5 (enExample) * 1973-12-27 1980-05-30 Siegfried Ag
FR2428629A1 (fr) * 1978-06-14 1980-01-11 Hexachimie Nouveaux composes bis(aryloxycarboxyliques), leur preparation et leur utilisation en therapeutique
EP0363760A1 (de) * 1988-10-12 1990-04-18 Bayer Ag Aromatische Ether
US5179097A (en) * 1991-06-10 1993-01-12 Angres Isaac A Salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
SI1413331T1 (sl) * 2001-01-26 2008-02-29 Schering Corp Kombinacije fenofibrata peroksisomskega proliferator aktivirajocega receptorja (PPAR) z ezetimib zaviralcem absorpcije sterola za vaskularne indikacije
US20020147184A1 (en) * 2001-01-26 2002-10-10 Schering Corporation Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
EP1785144A3 (en) * 2001-01-26 2007-05-23 Shering Corporation Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
EP1911462A3 (en) 2001-01-26 2011-11-30 Schering Corporation Compositions comprising a sterol absorption inhibitor
JP4711600B2 (ja) * 2001-01-26 2011-06-29 シェーリング コーポレイション シトステロール血症の処置のための置換アゼチジノン化合物の使用
DK1385548T3 (da) * 2001-01-26 2007-09-10 Schering Corp Kombinationer af sterolabsorptionsinhibitor(er) med (et eller flere) kardiovaskulære midler til behandling af vaskulære tilstande
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
CA2434488A1 (en) * 2001-01-26 2002-08-01 Harry R. Davis Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
WO2002096415A2 (en) * 2001-05-25 2002-12-05 Schering Corporation Use of azetidinone substituted derivatives in the treatment of alzheimer's disease
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
ATE411018T1 (de) * 2001-09-21 2008-10-15 Schering Corp Verfahren zur behandlung oder verhinderung von vaskulärer entzündung mit sterol-absorbierungs- inhibitor(en)
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7132415B2 (en) * 2001-09-21 2006-11-07 Schering Corporation Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
CA2504878A1 (en) * 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorption inhibitors for the treatment of demyelination
CN100439361C (zh) 2003-03-07 2008-12-03 先灵公司 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
CN1756755A (zh) * 2003-03-07 2006-04-05 先灵公司 取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4589919B2 (ja) * 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
NZ577031A (en) * 2003-05-30 2010-09-30 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as HMG-CO inhibitors
EP1680189A2 (en) * 2003-11-05 2006-07-19 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
US6998397B2 (en) * 2004-07-23 2006-02-14 Drebsk Comptech, Inc. Method for decreasing cholesterol level in blood
WO2007054896A1 (en) * 2005-11-08 2007-05-18 Ranbaxy Laboratories Limited Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
TW200744583A (en) * 2006-03-14 2007-12-16 Ranbaxy Lab Ltd Statin stabilizing dosage formulations
EP2049102A4 (en) * 2006-07-14 2010-12-22 Ranbaxy Lab Ltd POLYMORPHIC FORMS OF AN HMG COA REDUCTASE HEATHER AND USE
AR065670A1 (es) 2007-03-09 2009-06-24 Indigene Pharmaceuticals Inc Combinacion de metformina r-(+) lipoato y agentes antihiperlipidemicos para el tratamiento de hiperglucemia diabetica y complicaciones diabeticas
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
AR103624A1 (es) 2015-02-06 2017-05-24 Intercept Pharmaceuticals Inc Composiciones farmacéuticas para terapia de combinación
CN104610051A (zh) * 2015-03-02 2015-05-13 北京万全德众医药生物技术有限公司 一种制备克利贝特杂质的方法
EA202193334A1 (ru) 2019-05-30 2022-03-14 Интерсепт Фармасьютикалз, Инк. Фармацевтические композиции, содержащие агонист fxr и фибрат, для применения при лечении холестатического заболевания печени

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2444594A (en) * 1947-08-07 1948-07-06 American Cyanamid Co Isopropylidene-p-phenoxy-2-ethanol-p-phenoxyacetic acid
US2541003A (en) * 1948-08-17 1951-02-06 American Cyanamid Co Process for reacting salts of phenols with halo-alkanoic acid compounds
GB860303A (en) * 1958-06-20 1961-02-01 Ici Ltd Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª
US3169144A (en) * 1960-08-12 1965-02-09 Massarani Elena Anticholesterinemic and antilipaemic agents
GB970969A (en) * 1963-08-15 1964-09-23 Shell Int Research Dicarboxylic acids and their esters and a process for the preparation thereof
FR1380816A (fr) * 1963-11-18 1964-12-04 Ciba Geigy Procédé de préparation de nouveaux acides isobutyriques, entre autres de l'acide alpha-[p-(2-p'-chlorophényl-propyl-[2])-phénoxy]-isobutyrique
US3470234A (en) * 1965-08-23 1969-09-30 Ciba Geigy Corp Diaryl substituted benzocycloalkanes
US3470235A (en) * 1965-11-05 1969-09-30 Eastman Kodak Co Alicyclic bisphenyleneoxydicarboxylic acids,salts and esters
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
US3630715A (en) * 1968-12-19 1971-12-28 Weston Chemical Corp Alkylene bis (phenoxyacetic acid) derivatives as herbicides
US3755603A (en) * 1970-07-01 1973-08-28 Syntex Corp Biphenylyloxyacetic acids in pharmaceutical compositions

Also Published As

Publication number Publication date
US3959484A (en) 1976-05-25
FI52570C (fi) 1977-10-10
CH539012A (de) 1973-08-31
AT302278B (de) 1972-10-10
FI52570B (enExample) 1977-06-30
CA964273A (en) 1975-03-11
FR2042333B1 (enExample) 1973-04-06
DK128731B (da) 1974-06-24
US3716583A (en) 1973-02-13
BE748970A (fr) 1970-09-16
NL7005400A (enExample) 1970-10-20
NL139016B (nl) 1973-06-15
CH556807A (de) 1974-12-13
FR2042333A1 (enExample) 1971-02-12

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time