AT303015B - Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze - Google Patents

Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze

Info

Publication number
AT303015B
AT303015B AT784271A AT784271A AT303015B AT 303015 B AT303015 B AT 303015B AT 784271 A AT784271 A AT 784271A AT 784271 A AT784271 A AT 784271A AT 303015 B AT303015 B AT 303015B
Authority
AT
Austria
Prior art keywords
amides
esters
salts
new
production
Prior art date
Application number
AT784271A
Other languages
English (en)
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2990769A external-priority patent/JPS5010299B1/ja
Priority claimed from JP2990569A external-priority patent/JPS5010298B1/ja
Priority claimed from JP8004269A external-priority patent/JPS5010308B1/ja
Priority claimed from JP10419469A external-priority patent/JPS4939995B1/ja
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Priority claimed from US00206966A external-priority patent/US3821404A/en
Application granted granted Critical
Publication of AT303015B publication Critical patent/AT303015B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT784271A 1969-04-16 1970-04-15 Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze AT303015B (de)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP2990769A JPS5010299B1 (de) 1969-04-16 1969-04-16
JP2990569A JPS5010298B1 (de) 1969-04-16 1969-04-16
JP3416769 1969-05-02
JP3416669 1969-05-02
JP8004269A JPS5010308B1 (de) 1969-10-03 1969-10-03
JP8004169 1969-10-03
JP10280969 1969-12-19
JP10419469A JPS4939995B1 (de) 1969-12-23 1969-12-23
US2641270A 1970-04-07 1970-04-07
US00206966A US3821404A (en) 1969-04-16 1971-12-10 Phenoxy carboxylic acid derivatives as anti-atherosclerosis agents

Publications (1)

Publication Number Publication Date
AT303015B true AT303015B (de) 1972-11-10

Family

ID=27579824

Family Applications (2)

Application Number Title Priority Date Filing Date
AT784271A AT303015B (de) 1969-04-16 1970-04-15 Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze
AT344070A AT302278B (de) 1969-04-16 1970-04-15 Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT344070A AT302278B (de) 1969-04-16 1970-04-15 Verfahren zur Herstellung neuer Phenoxyalkansäuren, deren Ester, Amide oder Salze

Country Status (9)

Country Link
US (2) US3716583A (de)
AT (2) AT303015B (de)
BE (1) BE748970A (de)
CA (1) CA964273A (de)
CH (2) CH539012A (de)
DK (1) DK128731B (de)
FI (1) FI52570C (de)
FR (1) FR2042333B1 (de)
NL (1) NL139016B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4092324A (en) * 1971-05-22 1978-05-30 Sumitomo Chemical Company, Limited Diheterocyclic esters of 4-(1,1-bis-(phenoxy-propionic or -butoyric acid)-cyclohexane)α-methyl substituted
US4008265A (en) * 1971-05-22 1977-02-15 Sumitomo Chemical Company, Limited Novel bisphenoxy carboxylic acid derivatives and their salts
JPS575214B2 (de) * 1972-06-01 1982-01-29
JPS4931651A (de) * 1972-07-20 1974-03-22
JPS5735171B2 (de) * 1973-07-02 1982-07-27
CH617417A5 (de) * 1973-12-27 1980-05-30 Siegfried Ag
AT353776B (de) * 1973-12-27 1979-12-10 Siegfried Ag Verfahren zur herstellung von neuen alkan- saeuren, deren estern und salzen
FR2428629A1 (fr) * 1978-06-14 1980-01-11 Hexachimie Nouveaux composes bis(aryloxycarboxyliques), leur preparation et leur utilisation en therapeutique
EP0363760A1 (de) * 1988-10-12 1990-04-18 Bayer Ag Aromatische Ether
US5179097A (en) * 1991-06-10 1993-01-12 Angres Isaac A Salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
IL156585A0 (en) * 2001-01-26 2004-01-04 Schering Corp Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions
CA2434033A1 (en) * 2001-01-26 2002-08-01 Schering Corporation Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
ES2290562T3 (es) * 2001-01-26 2008-02-16 Schering Corporation Combinaciones del activador del receptor activado por el proliferador de los peroxisomas (ppar) fenofibrato con el inhibidor de la absorcion de esteroles ezetimiba para indicaciones vasculares.
KR20070120617A (ko) * 2001-01-26 2007-12-24 쉐링 코포레이션 치환된 아제티딘온 화합물을 포함하는 약제학적 조성물
KR20040025890A (ko) * 2001-01-26 2004-03-26 쉐링 코포레이션 혈관성 질환을 치료하기 위한 스테롤 흡수 억제제와 혈액조절제의 조합물
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
EP1911462A3 (de) 2001-01-26 2011-11-30 Schering Corporation Zusammensetzungen enthaltend einen Sterolabsorptionshemmer
CA2434488A1 (en) * 2001-01-26 2002-08-01 Harry R. Davis Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
US20030013699A1 (en) * 2001-05-25 2003-01-16 Davis Harry R. Methods for treating alzheimer's disease and/or regulating levels of amyloid beta peptides in a subject
US7132415B2 (en) * 2001-09-21 2006-11-07 Schering Corporation Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
ES2312624T3 (es) * 2001-09-21 2009-03-01 Schering Corporation Metodos para tratar o prevenir la inflamacion vascular usando un inhibidor (inhibidores) de la absorcion de esterol.
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
MXPA05004810A (es) * 2002-11-06 2005-07-22 Schering Corp Inhibidores de la absorcion del colesterol para el tratamiento de la desmielinizacion.
ATE406364T1 (de) * 2003-03-07 2008-09-15 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
WO2004081004A1 (en) * 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
EP1601669B1 (de) * 2003-03-07 2008-12-24 Schering Corporation Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
JP4901474B2 (ja) * 2003-05-30 2012-03-21 ランバクシー ラボラトリーズ リミテッド 置換ピロール誘導体
EP1680189A2 (de) * 2003-11-05 2006-07-19 Schering Corporation Kombinationen von lipidmodulierenden mitteln mit substituierten azetidinonen zur behandlung von vaskularen erkrankungen
US6998397B2 (en) * 2004-07-23 2006-02-14 Drebsk Comptech, Inc. Method for decreasing cholesterol level in blood
KR101329112B1 (ko) 2005-11-08 2013-11-14 랜박시 래보러터리스 리미티드 (3r,5r)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
AR059838A1 (es) * 2006-03-14 2008-04-30 Ranbaxy Lab Ltd Formulaciones para dosis estabilizantes de estatina
US20080153896A1 (en) * 2006-07-14 2008-06-26 Gyan Chand Yadav Polymorphic Forms of an HMG-CoA Reductase Inhibitor and Uses Thereof
WO2008112166A2 (en) 2007-03-09 2008-09-18 Indigene Pharmaceuticals Inc. Combination of metformin r-(+) lipoate and antihyperlipidemic agents for the treatment of diabetic hyperglycemia and diabetic complications
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
BR112017016766B1 (pt) 2015-02-06 2023-11-07 Intercept Pharmaceuticals, Inc Composição compreendendo um agonista fxr e fibrato, bem como uso para tratar doença hepática colestática
CN104610051A (zh) * 2015-03-02 2015-05-13 北京万全德众医药生物技术有限公司 一种制备克利贝特杂质的方法
JP2022536060A (ja) 2019-05-30 2022-08-12 インターセプト ファーマシューティカルズ, インコーポレイテッド 胆汁鬱滞性肝疾患の処置で使用するためのfxrアゴニストおよびフィブラートを含む医薬組成物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2444594A (en) * 1947-08-07 1948-07-06 American Cyanamid Co Isopropylidene-p-phenoxy-2-ethanol-p-phenoxyacetic acid
US2541003A (en) * 1948-08-17 1951-02-06 American Cyanamid Co Process for reacting salts of phenols with halo-alkanoic acid compounds
GB860303A (en) * 1958-06-20 1961-02-01 Ici Ltd Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª
US3169144A (en) * 1960-08-12 1965-02-09 Massarani Elena Anticholesterinemic and antilipaemic agents
GB970969A (en) * 1963-08-15 1964-09-23 Shell Int Research Dicarboxylic acids and their esters and a process for the preparation thereof
FR1380816A (fr) * 1963-11-18 1964-12-04 Ciba Geigy Procédé de préparation de nouveaux acides isobutyriques, entre autres de l'acide alpha-[p-(2-p'-chlorophényl-propyl-[2])-phénoxy]-isobutyrique
US3470234A (en) * 1965-08-23 1969-09-30 Ciba Geigy Corp Diaryl substituted benzocycloalkanes
US3470235A (en) * 1965-11-05 1969-09-30 Eastman Kodak Co Alicyclic bisphenyleneoxydicarboxylic acids,salts and esters
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
US3630715A (en) * 1968-12-19 1971-12-28 Weston Chemical Corp Alkylene bis (phenoxyacetic acid) derivatives as herbicides
US3755603A (en) * 1970-07-01 1973-08-28 Syntex Corp Biphenylyloxyacetic acids in pharmaceutical compositions

Also Published As

Publication number Publication date
DK128731B (da) 1974-06-24
US3959484A (en) 1976-05-25
FI52570B (de) 1977-06-30
FR2042333A1 (de) 1971-02-12
CA964273A (en) 1975-03-11
CH539012A (de) 1973-08-31
NL7005400A (de) 1970-10-20
AT302278B (de) 1972-10-10
FI52570C (fi) 1977-10-10
NL139016B (nl) 1973-06-15
BE748970A (fr) 1970-09-16
FR2042333B1 (de) 1973-04-06
US3716583A (en) 1973-02-13
CH556807A (de) 1974-12-13

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time