AR245940A1 - Procedimiento para obtener nuevos derivados del cromano. - Google Patents
Procedimiento para obtener nuevos derivados del cromano.Info
- Publication number
- AR245940A1 AR245940A1 AR90317320A AR31732090A AR245940A1 AR 245940 A1 AR245940 A1 AR 245940A1 AR 90317320 A AR90317320 A AR 90317320A AR 31732090 A AR31732090 A AR 31732090A AR 245940 A1 AR245940 A1 AR 245940A1
- Authority
- AR
- Argentina
- Prior art keywords
- compound
- formula
- bencilo
- substituted
- chroman derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER NUEVOS DERIVADOS DEL CROMANO, DE FORMULA (I), EN LA QUE R1 ES A; R2 Y R8 SON H O A, Y TAMBIEN R1 JUNTO CON R2 FORMAN ALQUILENO (C3-6); R3 ES H, OH, OA U OAC; R4 ES H Y TAMBIEN R3 JUNTO CON R4 FORMAN UNA LIGADURA; R5 ES H, A O BENCILO, SUSTITUIDO O NO UNA, DOS O TRES VECES CON A Y/U OA;CON UN COMPUESTO DE FORMULA (III), EN LA QUE R11 ES A O BENCILO SUSTITUIDO O NO DE 1 A 3 VECES CON A Y/U OA, Y PARA OBTENER UN COMPUESTO DE FORMULA (I) EN LA QUE R5 ES HIDROGENO, SE TRATA CON UN AGENTE HIDROGENOLITICO O SOLVOLITICO, UN COMPUESTO, QUE EN LUGAR DE R5 LLEVA UN GRUPO PROTECTOR, ELIMINABLE POR HIDROGENOLISIS O SOLVOLISIS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3922392A DE3922392A1 (de) | 1989-07-07 | 1989-07-07 | Chromanderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR245940A1 true AR245940A1 (es) | 1994-03-30 |
Family
ID=6384507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR90317320A AR245940A1 (es) | 1989-07-07 | 1990-07-06 | Procedimiento para obtener nuevos derivados del cromano. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5112839A (es) |
| EP (1) | EP0406656B1 (es) |
| JP (1) | JPH0344389A (es) |
| KR (1) | KR910002842A (es) |
| AR (1) | AR245940A1 (es) |
| AT (1) | ATE116985T1 (es) |
| AU (1) | AU622338B2 (es) |
| CA (1) | CA2020553A1 (es) |
| DE (2) | DE3922392A1 (es) |
| DK (1) | DK0406656T3 (es) |
| ES (1) | ES2066913T3 (es) |
| FI (1) | FI95131C (es) |
| HU (1) | HUT58726A (es) |
| IE (1) | IE902477A1 (es) |
| IL (1) | IL94987A (es) |
| NO (1) | NO176099C (es) |
| NZ (1) | NZ234395A (es) |
| PT (1) | PT94629B (es) |
| ZA (1) | ZA905325B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5387587A (en) * | 1986-12-23 | 1995-02-07 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
| US5284838A (en) * | 1987-06-23 | 1994-02-08 | Elf Sanofi | Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma |
| KR950009863B1 (ko) * | 1991-05-22 | 1995-08-29 | 재단법인한국화학연구소 | 벤조피란 유도체와 그의 제조방법 |
| FR2698873B1 (fr) * | 1992-12-07 | 1995-02-24 | Lipha | Benzocycloheptènes, benzoxépines et benzothiépines activateurs des canaux potassiques, procédé de préparation, composition pharmaceutique les contenant. |
| EP0677519A4 (en) * | 1993-11-10 | 1996-04-03 | Japan Tobacco Inc | CHROMAN DERIVATIVE AND THERAPEUTIC USE THEREOF. |
| US5470861A (en) * | 1994-08-04 | 1995-11-28 | Hoffmann-La Roche Inc. | Method of promoting hair growth |
| AU2002351412B2 (en) | 2001-12-21 | 2010-05-20 | Exelixis Patent Company Llc | Modulators of LXR |
| US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| WO2007027780A2 (en) * | 2005-09-01 | 2007-03-08 | Janssen Pharmaceutica N.V. | Benzopyran and pyranopyridine derivatives as potassium channel openers |
| ES2379098T3 (es) | 2005-09-01 | 2012-04-20 | Janssen Pharmaceutica Nv | Derivados de benzopirano novedosos como abridores del canal de potasio |
| KR100559450B1 (ko) * | 2005-12-31 | 2006-03-10 | 이삼준 | 안전모 및 모자용 착탈그늘막 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2107706A (en) | 1981-09-25 | 1983-05-05 | Beecham Group Plc | Benzopyrans |
| GB8308062D0 (en) | 1983-03-24 | 1983-05-05 | Beecham Group Plc | Active compounds |
| GB8419516D0 (en) | 1984-07-31 | 1984-09-05 | Beecham Group Plc | Treatment |
| GB8419515D0 (en) | 1984-07-31 | 1984-09-05 | Beecham Group Plc | Treatment |
| DE3669317D1 (de) * | 1985-09-11 | 1990-04-12 | Beecham Group Plc | Chromanderivate und aehnliche verbindungen mit blutdrucksenkender wirkung. |
| JPH07110806B2 (ja) | 1986-08-08 | 1995-11-29 | ジ・アップジョン・カンパニー | 脱毛症を治療するための組成物 |
| DE3726261A1 (de) * | 1986-12-23 | 1988-07-07 | Merck Patent Gmbh | Chromanderivate |
| US4971982A (en) * | 1987-07-06 | 1990-11-20 | Hoffmann-La Roche Inc. | Benzopyran derivatives |
| DE3924417A1 (de) * | 1989-07-24 | 1991-01-31 | Merck Patent Gmbh | Chromanderivate |
-
1989
- 1989-07-07 DE DE3922392A patent/DE3922392A1/de not_active Withdrawn
-
1990
- 1990-06-25 DE DE59008224T patent/DE59008224D1/de not_active Expired - Fee Related
- 1990-06-25 EP EP90111996A patent/EP0406656B1/de not_active Expired - Lifetime
- 1990-06-25 AT AT90111996T patent/ATE116985T1/de not_active IP Right Cessation
- 1990-06-25 ES ES90111996T patent/ES2066913T3/es not_active Expired - Lifetime
- 1990-06-25 DK DK90111996.6T patent/DK0406656T3/da active
- 1990-07-05 CA CA002020553A patent/CA2020553A1/en not_active Abandoned
- 1990-07-05 IL IL9498790A patent/IL94987A/en not_active IP Right Cessation
- 1990-07-05 AU AU58725/90A patent/AU622338B2/en not_active Ceased
- 1990-07-06 JP JP2177647A patent/JPH0344389A/ja active Pending
- 1990-07-06 PT PT94629A patent/PT94629B/pt not_active IP Right Cessation
- 1990-07-06 KR KR1019900010222A patent/KR910002842A/ko not_active Application Discontinuation
- 1990-07-06 NZ NZ234395A patent/NZ234395A/xx unknown
- 1990-07-06 US US07/549,043 patent/US5112839A/en not_active Expired - Fee Related
- 1990-07-06 IE IE247790A patent/IE902477A1/en unknown
- 1990-07-06 NO NO903043A patent/NO176099C/no unknown
- 1990-07-06 ZA ZA905325A patent/ZA905325B/xx unknown
- 1990-07-06 FI FI903431A patent/FI95131C/fi not_active IP Right Cessation
- 1990-07-06 AR AR90317320A patent/AR245940A1/es active
- 1990-07-06 HU HU904114A patent/HUT58726A/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2020553A1 (en) | 1991-01-08 |
| DE59008224D1 (de) | 1995-02-23 |
| PT94629A (pt) | 1991-03-20 |
| NO903043L (no) | 1991-01-08 |
| JPH0344389A (ja) | 1991-02-26 |
| ES2066913T3 (es) | 1995-03-16 |
| IL94987A (en) | 1996-01-19 |
| EP0406656A1 (de) | 1991-01-09 |
| NO176099C (no) | 1995-02-01 |
| ATE116985T1 (de) | 1995-01-15 |
| ZA905325B (en) | 1991-04-24 |
| NO903043D0 (no) | 1990-07-06 |
| DK0406656T3 (da) | 1995-03-27 |
| NZ234395A (en) | 1991-08-27 |
| EP0406656B1 (de) | 1995-01-11 |
| IE902477A1 (en) | 1991-02-13 |
| DE3922392A1 (de) | 1991-01-17 |
| NO176099B (no) | 1994-10-24 |
| FI95131B (fi) | 1995-09-15 |
| AU5872590A (en) | 1991-01-10 |
| HUT58726A (en) | 1992-03-30 |
| FI95131C (fi) | 1995-12-27 |
| FI903431A0 (fi) | 1990-07-06 |
| AU622338B2 (en) | 1992-04-02 |
| IL94987A0 (en) | 1991-06-10 |
| PT94629B (pt) | 1997-06-30 |
| HU904114D0 (en) | 1990-12-28 |
| KR910002842A (ko) | 1991-02-26 |
| US5112839A (en) | 1992-05-12 |
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