AR228941A1 - Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos - Google Patents
Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicosInfo
- Publication number
- AR228941A1 AR228941A1 AR276253A AR27625379A AR228941A1 AR 228941 A1 AR228941 A1 AR 228941A1 AR 276253 A AR276253 A AR 276253A AR 27625379 A AR27625379 A AR 27625379A AR 228941 A1 AR228941 A1 AR 228941A1
- Authority
- AR
- Argentina
- Prior art keywords
- diamino
- triazole
- procedure
- active against
- new derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/12—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1646878 | 1978-04-26 | ||
GB7847689 | 1978-12-08 | ||
GB7907422 | 1979-03-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR228941A1 true AR228941A1 (es) | 1983-05-13 |
Family
ID=27257387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR276253A AR228941A1 (es) | 1978-04-26 | 1979-04-20 | Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos |
Country Status (20)
Country | Link |
---|---|
US (3) | US4318913A (no) |
AR (1) | AR228941A1 (no) |
AT (1) | AT376212B (no) |
AU (1) | AU531224B2 (no) |
CA (1) | CA1143727A (no) |
CH (1) | CH647767A5 (no) |
DE (2) | DE2917026A1 (no) |
DK (1) | DK173579A (no) |
ES (4) | ES8102104A1 (no) |
FI (1) | FI791360A (no) |
FR (1) | FR2432511B1 (no) |
IL (1) | IL57178A (no) |
IT (1) | IT1162304B (no) |
LU (1) | LU81192A1 (no) |
NL (1) | NL7903313A (no) |
NO (1) | NO791387L (no) |
NZ (1) | NZ190299A (no) |
PH (1) | PH19534A (no) |
SE (1) | SE7903698L (no) |
YU (2) | YU100379A (no) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR228941A1 (es) * | 1978-04-26 | 1983-05-13 | Glaxo Group Ltd | Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos |
DK89480A (da) * | 1979-03-02 | 1980-09-03 | Glaxo Group Ltd | R fremgangsmaade til fremstilling af heterocycliske forbindelse |
EP0028483B1 (en) * | 1979-10-22 | 1984-04-18 | Glaxo Group Limited | 1,2,4-triazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing them |
US4777179A (en) * | 1979-10-23 | 1988-10-11 | Glaxo Group Limited | Heterocyclic derivatives, processes for the use thereof and pharmaceutical compositions containing them |
CH655104A5 (fr) * | 1980-02-28 | 1986-03-27 | Glaxo Group Ltd | Derives heterocycliques triazoliques, procedes pour leur preparation et compositions pharmaceutiques les comportant. |
AU548426B2 (en) * | 1980-08-27 | 1985-12-12 | Glaxo Group Limited | 3-amino-(1,2,4)-triazoles |
EP0055625B1 (en) * | 1980-12-30 | 1985-05-02 | Glaxo Group Limited | Process for the preparation of a furan derivative |
DK558181A (da) * | 1981-01-30 | 1982-07-31 | Smithkline Corp | Fremgangsmaade til fremstilling af 3,5-diamino-1,2,4-triazoler |
US4522943A (en) * | 1981-05-18 | 1985-06-11 | Bristol-Myers Company | Chemical compounds |
US4526973A (en) * | 1981-05-18 | 1985-07-02 | Bristol-Myers Company | Chemical compounds |
IE53068B1 (en) * | 1981-06-15 | 1988-05-25 | Merck & Co Inc | Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors |
EP0070743A3 (en) * | 1981-07-22 | 1983-10-12 | Glaxo Group Limited | Pharmaceutical compositions containing compounds having action on histamine receptors |
CA1192545A (en) * | 1982-02-16 | 1985-08-27 | Glaxo Group Limited | Heterocyclic derivatives as histamine h.sub.2- antagonists |
KR840003621A (ko) * | 1982-02-24 | 1984-09-15 | 원본미기재 | 헤테로 사이클릭 유도체의 제조방법 |
US4482552A (en) * | 1982-02-26 | 1984-11-13 | Glaxo Group Limited | Triazole compounds and their pharmaceutical use |
EP0089153B1 (en) * | 1982-03-17 | 1986-09-24 | Smith Kline & French Laboratories Limited | Pyridine derivatives |
US4520025A (en) * | 1982-07-21 | 1985-05-28 | William H. Rorer, Inc. | Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses |
US4543352A (en) * | 1983-04-29 | 1985-09-24 | William H. Rorer, Inc. | Naphthalene aminoalkylene ethers and thioethers, and their pharmaceutical uses |
US4529723A (en) * | 1983-04-29 | 1985-07-16 | William H. Rorer, Inc. | Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use |
US4481360A (en) * | 1983-08-26 | 1984-11-06 | The Upjohn Company | 4H-1,2,4-Triazol-3-yl compounds |
DE3336410A1 (de) * | 1983-10-06 | 1985-04-18 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3404786A1 (de) * | 1984-02-10 | 1985-08-14 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Neue alkanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltendes arzneimittel |
US4812451A (en) * | 1984-10-19 | 1989-03-14 | A. H. Robins Company, Incorporated | 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha. |
US4812452A (en) * | 1984-10-19 | 1989-03-14 | A. H. Robins Company, Incorporated | 1-((aminoalkyl and aminoalkylamino) carbonyl and thiocarbonyl)-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles |
DE3568374D1 (en) * | 1985-12-20 | 1989-03-30 | Litef Gmbh | Method to determine heading by using and automatically calibrating a 3-axis magnetometer rigidly fitted in an aircraft |
US4988828A (en) * | 1987-11-27 | 1991-01-29 | Fujirebio Kabushiki Kaisha | Phenoxypropyl derivatives |
US5028716A (en) * | 1989-01-30 | 1991-07-02 | Taisho Pharmaceutical Co., Ltd. | 3,5-diamino-1,2,4-triazole derivatives |
GB9009437D0 (en) * | 1990-04-26 | 1990-06-20 | Glaxo Group Ltd | Chemical compounds |
WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1419994A (en) | 1973-05-03 | 1976-01-07 | Smith Kline French Lab | Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them |
SU557574A1 (ru) | 1975-07-02 | 1978-03-05 | Ордена Трудового Красного Знамени Научно-Исследовательский Институт Экспериментальной Медицины Амн Ссср | Способ получени 3-амино-5-(2-аминоэтил)-1,2,4-триазола |
SU596577A1 (ru) | 1976-02-23 | 1978-03-05 | Ордена Трудового Красного Знамени Научно-Исследовательский Институт Экспериментальной Медицины | -Метил- "/4-(5 амино-1,2,4триазолил-3)-бутил/-тиомочевина, про вл юща антигистаминовую активность, и способ ее получени |
GB1565966A (en) * | 1976-08-04 | 1980-04-23 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
GB1601459A (en) * | 1977-05-17 | 1981-10-28 | Allen & Hanburys Ltd | Aminoalkyl thiophene derivatives |
IE46886B1 (en) * | 1977-05-17 | 1983-10-19 | Allen & Hanburys Ltd | Aminoalkyl-benzene derivatives |
US4115860A (en) * | 1977-06-02 | 1978-09-19 | Lockheed Electronics Co., Inc. | Plural load power controller with time-shared processor |
DE2835695A1 (de) | 1977-08-29 | 1979-03-15 | Yamanouchi Pharma Co Ltd | Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten |
AR228941A1 (es) * | 1978-04-26 | 1983-05-13 | Glaxo Group Ltd | Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos |
US4293557A (en) * | 1979-07-03 | 1981-10-06 | Teikoku Hormone Mfg. Co., Ltd. | Antiulcer phenoxypropylamine derivatives |
DE3175201D1 (en) * | 1980-04-30 | 1986-10-02 | Merck & Co Inc | Aminothiadiazoles as gastric secretion inhibitors |
US4390701A (en) * | 1981-05-18 | 1983-06-28 | Bristol-Myers Company | 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione |
GR77847B (no) * | 1981-12-14 | 1984-09-25 | American Home Prod | |
JPS6067474A (ja) * | 1983-09-24 | 1985-04-17 | Wakamoto Pharmaceut Co Ltd | 新規な1,3,4−チアジアゾ−ル誘導体及びそれを有効成分とする抗潰瘍剤 |
DE3513184A1 (de) * | 1985-04-12 | 1986-10-16 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | 1,3,4-thiadiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1979
- 1979-04-20 AR AR276253A patent/AR228941A1/es active
- 1979-04-25 FR FR7910459A patent/FR2432511B1/fr not_active Expired
- 1979-04-25 CH CH3909/79A patent/CH647767A5/de not_active IP Right Cessation
- 1979-04-26 AU AU46482/79A patent/AU531224B2/en not_active Ceased
- 1979-04-26 FI FI791360A patent/FI791360A/fi not_active Application Discontinuation
- 1979-04-26 DE DE19792917026 patent/DE2917026A1/de not_active Ceased
- 1979-04-26 ES ES479988A patent/ES8102104A1/es not_active Expired
- 1979-04-26 CA CA000326446A patent/CA1143727A/en not_active Expired
- 1979-04-26 NO NO791387A patent/NO791387L/no unknown
- 1979-04-26 US US06/033,508 patent/US4318913A/en not_active Expired - Lifetime
- 1979-04-26 PH PH22427A patent/PH19534A/en unknown
- 1979-04-26 DK DK173579A patent/DK173579A/da active IP Right Grant
- 1979-04-26 IT IT48856/79A patent/IT1162304B/it active
- 1979-04-26 SE SE7903698A patent/SE7903698L/xx not_active Application Discontinuation
- 1979-04-26 LU LU81192A patent/LU81192A1/fr unknown
- 1979-04-26 NZ NZ190299A patent/NZ190299A/xx unknown
- 1979-04-26 YU YU01003/79A patent/YU100379A/xx unknown
- 1979-04-26 AT AT0316679A patent/AT376212B/de not_active IP Right Cessation
- 1979-04-26 NL NL7903313A patent/NL7903313A/xx not_active Application Discontinuation
- 1979-04-26 DE DE2954639A patent/DE2954639C2/de not_active Expired - Fee Related
- 1979-04-30 IL IL57178A patent/IL57178A/xx unknown
-
1980
- 1980-02-16 ES ES488676A patent/ES8101563A1/es not_active Expired
- 1980-02-16 ES ES488678A patent/ES8101565A1/es not_active Expired
- 1980-02-16 ES ES488677A patent/ES8101564A1/es not_active Expired
-
1981
- 1981-11-24 US US06/324,440 patent/US4442110A/en not_active Expired - Fee Related
-
1983
- 1983-01-25 YU YU00161/83A patent/YU16183A/xx unknown
-
1986
- 1986-02-06 US US06/826,832 patent/US4764612A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US4318913A (en) | 1982-03-09 |
FR2432511A1 (fr) | 1980-02-29 |
ES479988A0 (es) | 1980-08-16 |
IT1162304B (it) | 1987-03-25 |
CH647767A5 (de) | 1985-02-15 |
YU16183A (en) | 1983-04-30 |
SE7903698L (sv) | 1979-10-27 |
DE2954639C2 (no) | 1990-09-27 |
ES8102104A1 (es) | 1980-08-16 |
DE2917026A1 (de) | 1979-11-08 |
ES488678A0 (es) | 1980-12-16 |
AT376212B (de) | 1984-10-25 |
YU100379A (en) | 1983-04-30 |
NZ190299A (en) | 1982-05-31 |
NL7903313A (nl) | 1979-10-30 |
ES488677A0 (es) | 1980-12-16 |
ES488676A0 (es) | 1980-12-16 |
ES8101563A1 (es) | 1980-12-16 |
DK173579A (da) | 1979-10-27 |
LU81192A1 (fr) | 1980-05-07 |
ES8101565A1 (es) | 1980-12-16 |
ATA316679A (de) | 1984-03-15 |
US4442110A (en) | 1984-04-10 |
US4764612A (en) | 1988-08-16 |
FR2432511B1 (fr) | 1986-04-25 |
PH19534A (en) | 1986-05-20 |
IT7948856A0 (it) | 1979-04-26 |
NO791387L (no) | 1979-10-29 |
IL57178A (en) | 1984-11-30 |
AU4648279A (en) | 1979-11-01 |
ES8101564A1 (es) | 1980-12-16 |
IL57178A0 (en) | 1979-07-25 |
FI791360A (fi) | 1979-10-27 |
AU531224B2 (en) | 1983-08-18 |
CA1143727A (en) | 1983-03-29 |
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