AR225881A1 - Procedimiento para obtener derivados de n-(2-pirrolidinil-metil)-5-sulfonamida-benzamina y sus cales - Google Patents
Procedimiento para obtener derivados de n-(2-pirrolidinil-metil)-5-sulfonamida-benzamina y sus calesInfo
- Publication number
- AR225881A1 AR225881A1 AR270868A AR27086878A AR225881A1 AR 225881 A1 AR225881 A1 AR 225881A1 AR 270868 A AR270868 A AR 270868A AR 27086878 A AR27086878 A AR 27086878A AR 225881 A1 AR225881 A1 AR 225881A1
- Authority
- AR
- Argentina
- Prior art keywords
- pirrolidinyl
- benzamine
- limes
- sulfonamide
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52008443A JPS5920667B2 (ja) | 1977-01-27 | 1977-01-27 | スルホンアミド系ベンズアミド誘導体 |
JP52094884A JPS5822110B2 (ja) | 1977-08-08 | 1977-08-08 | ベンズアミド誘導体の合成法 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR225881A1 true AR225881A1 (es) | 1982-05-14 |
Family
ID=26342958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR270868A AR225881A1 (es) | 1977-01-27 | 1978-01-26 | Procedimiento para obtener derivados de n-(2-pirrolidinil-metil)-5-sulfonamida-benzamina y sus cales |
Country Status (18)
Country | Link |
---|---|
US (6) | US4351770A (fr) |
AR (1) | AR225881A1 (fr) |
AU (1) | AU512057B2 (fr) |
CA (1) | CA1085411A (fr) |
CH (1) | CH642945A5 (fr) |
DE (1) | DE2803651A1 (fr) |
DK (1) | DK154137C (fr) |
ES (1) | ES466366A1 (fr) |
FR (1) | FR2378758A1 (fr) |
GB (1) | GB1557019A (fr) |
GR (1) | GR70058B (fr) |
HU (1) | HU176613B (fr) |
IE (1) | IE46497B1 (fr) |
IL (1) | IL53881A (fr) |
NL (1) | NL7801005A (fr) |
NZ (1) | NZ186175A (fr) |
PH (1) | PH12853A (fr) |
SE (1) | SE426485B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2440946A2 (fr) * | 1978-01-20 | 1980-06-06 | Ile De France | Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement |
FR2485526A1 (fr) * | 1980-06-24 | 1981-12-31 | Shionogi & Co | Procede de preparation de derives de n-(diethylaminoethyl)-2 - alcoxybenzamide, nouveaux produits ainsi obtenus et leurs utilisations comme produits pharmaceutiques antiemetiques ou pour guerir les troubles gastriques |
SE8101536L (sv) * | 1981-03-11 | 1982-09-12 | Astra Laekemedel Ab | Bensamid-derivat |
PT77219B (fr) * | 1982-08-24 | 1986-02-04 | May & Baker Ltd | Procede de preparation des derives de la benzamide |
SE8205135D0 (sv) * | 1982-09-09 | 1982-09-09 | Astra Laekemedel Ab | Benzamido-derivatives |
FR2550447B1 (fr) * | 1983-08-10 | 1986-01-17 | Ile De France | Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire |
DE3445377A1 (de) * | 1983-12-23 | 1985-07-04 | Sandoz-Patent-GmbH, 7850 Lörrach | Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen |
AU567140B2 (en) * | 1984-01-06 | 1987-11-12 | Shionogi & Co., Ltd. | Sulphonamido-benzamide derivatives |
US4544654A (en) * | 1984-03-20 | 1985-10-01 | Schering A.G. | Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof |
CA2057324A1 (fr) * | 1990-12-18 | 1992-06-19 | Lora Louise Fitch | Agents hypoglycemiques de type benzamide et sulfonamide |
ID29067A (id) * | 1998-11-20 | 2001-07-26 | Hoffmann La Roche | Turunan pirolidina-antagonis reseptor ccr-3 |
CL2009000448A1 (es) | 2008-02-29 | 2009-11-27 | Genentech Inc | Compuestos derivados de 3-sulfonilamino-n-(1h-pirazolo-[3,4-b]piridin-5il)benzamida; procesos de preparacion; compuestos intermediarios; composicion farmaceutica; y uso para el tratamiento del cancer, tal como sarcoma, carcinoma, adenoma, entre otros. |
CA2716947A1 (fr) * | 2008-02-29 | 2009-09-11 | Array Biopharma Inc. | Derives d'imidazo[4,5-b]pyridine utilises comme inhibiteurs de raf |
WO2009111280A1 (fr) | 2008-02-29 | 2009-09-11 | Array Biopharma Inc. | Dérivés de n-(6-aminopyridin-3-yl)-3-(sulfonamido) benzamide comme inhibiteurs de b-raf pour le traitement du cancer |
CN102015707A (zh) | 2008-02-29 | 2011-04-13 | 阵列生物制药公司 | Raf抑制剂化合物及其使用方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2334186A (en) * | 1938-12-20 | 1943-11-16 | Du Pont | Organic sulphonamides and their preparation |
FR148F (fr) * | 1962-01-24 | |||
US3342826A (en) * | 1964-01-13 | 1967-09-19 | Ile De France | Heterocyclic aminoalkyl benzamides |
US3210370A (en) * | 1964-06-22 | 1965-10-05 | Upjohn Co | Process for preparing 2, 2'-methylene-bisareneimiazoles |
FR5916M (fr) * | 1966-01-21 | 1968-05-06 | ||
FR2313935A1 (fr) * | 1975-06-10 | 1977-01-07 | Ile De France | Nouveaux benzamides substitues, leurs derives et leur procede de preparation |
CH547797A (de) * | 1971-08-20 | 1974-04-11 | Fratmann Ag | Verfahren zur herstellung von n - ((1-aethyl-pyrrolidinyl2)-methyl) -2-methoxy-5-sulfamoyl-benzamid. |
US4021229A (en) * | 1972-09-05 | 1977-05-03 | Stauffer Chemical Company | Sulfonamide herbicide antidote compositions and method of use |
CH605793A5 (fr) * | 1974-03-05 | 1978-10-13 | Ile De France | |
IL46696A (en) * | 1974-03-05 | 1978-07-31 | Ile De France | Substituted n-(2-pyrrolidinylalkyl)benzamides, their preparation and pharmaceutical compositions containing them |
FR2294698A1 (fr) * | 1974-12-18 | 1976-07-16 | Synthelabo | Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment |
-
1978
- 1978-01-09 NZ NZ186175A patent/NZ186175A/xx unknown
- 1978-01-19 CA CA295,322A patent/CA1085411A/fr not_active Expired
- 1978-01-19 GB GB2296/78A patent/GB1557019A/en not_active Expired
- 1978-01-21 GR GR55228A patent/GR70058B/el unknown
- 1978-01-23 IE IE145/78A patent/IE46497B1/en unknown
- 1978-01-24 AU AU32687/78A patent/AU512057B2/en not_active Expired
- 1978-01-24 IL IL53881A patent/IL53881A/xx unknown
- 1978-01-25 DK DK037278A patent/DK154137C/da not_active IP Right Cessation
- 1978-01-26 CH CH86678A patent/CH642945A5/de not_active IP Right Cessation
- 1978-01-26 SE SE7800982A patent/SE426485B/sv not_active IP Right Cessation
- 1978-01-26 HU HU78SI1614A patent/HU176613B/hu not_active IP Right Cessation
- 1978-01-26 AR AR270868A patent/AR225881A1/es active
- 1978-01-26 FR FR7802210A patent/FR2378758A1/fr active Granted
- 1978-01-26 ES ES466366A patent/ES466366A1/es not_active Expired
- 1978-01-26 PH PH20712A patent/PH12853A/en unknown
- 1978-01-27 DE DE19782803651 patent/DE2803651A1/de active Granted
- 1978-01-27 NL NL7801005A patent/NL7801005A/xx not_active Application Discontinuation
- 1978-12-06 US US05/967,011 patent/US4351770A/en not_active Expired - Lifetime
-
1980
- 1980-02-26 US US06/124,727 patent/US4328155A/en not_active Expired - Lifetime
- 1980-02-26 US US06/124,726 patent/US4350635A/en not_active Expired - Lifetime
- 1980-02-26 US US06/124,728 patent/US4328344A/en not_active Expired - Lifetime
- 1980-06-25 US US06/162,793 patent/US4330472A/en not_active Expired - Lifetime
-
1982
- 1982-07-15 US US06/398,702 patent/US4431663A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US4350635A (en) | 1982-09-21 |
CH642945A5 (de) | 1984-05-15 |
SE7800982L (sv) | 1978-07-28 |
DK154137B (da) | 1988-10-17 |
GB1557019A (en) | 1979-12-05 |
HU176613B (en) | 1981-03-28 |
US4328344A (en) | 1982-05-04 |
DE2803651A1 (de) | 1978-08-03 |
IE780145L (en) | 1978-07-27 |
GR70058B (fr) | 1982-07-26 |
US4351770A (en) | 1982-09-28 |
US4431663A (en) | 1984-02-14 |
SE426485B (sv) | 1983-01-24 |
DK154137C (da) | 1989-04-10 |
IL53881A (en) | 1981-05-20 |
NZ186175A (en) | 1980-03-05 |
AU512057B2 (en) | 1980-09-18 |
PH12853A (en) | 1979-09-12 |
DK37278A (da) | 1978-07-28 |
IE46497B1 (en) | 1983-06-29 |
ES466366A1 (es) | 1978-10-01 |
CA1085411A (fr) | 1980-09-09 |
NL7801005A (nl) | 1978-07-31 |
AU3268778A (en) | 1979-08-02 |
US4328155A (en) | 1982-05-04 |
FR2378758B1 (fr) | 1981-02-06 |
DE2803651C2 (fr) | 1988-10-20 |
US4330472A (en) | 1982-05-18 |
FR2378758A1 (fr) | 1978-08-25 |
IL53881A0 (en) | 1978-04-30 |
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