AR223863A1 - Procedimiento para preparar derivados n-sustituidos del acido aziridina-2-carboxilico - Google Patents
Procedimiento para preparar derivados n-sustituidos del acido aziridina-2-carboxilicoInfo
- Publication number
- AR223863A1 AR223863A1 AR279976A AR27997681A AR223863A1 AR 223863 A1 AR223863 A1 AR 223863A1 AR 279976 A AR279976 A AR 279976A AR 27997681 A AR27997681 A AR 27997681A AR 223863 A1 AR223863 A1 AR 223863A1
- Authority
- AR
- Argentina
- Prior art keywords
- aziridine
- preparing
- procedure
- carboxylic acid
- substituted derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792906603 DE2906603A1 (de) | 1979-02-21 | 1979-02-21 | N-substituierte aziridin-2-carbonsaeurederivate, verfahren zu deren herstellung sowie diese substanzen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR223863A1 true AR223863A1 (es) | 1981-09-30 |
Family
ID=6063481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR279976A AR223863A1 (es) | 1979-02-21 | 1981-02-15 | Procedimiento para preparar derivados n-sustituidos del acido aziridina-2-carboxilico |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4397848A (enExample) |
| EP (1) | EP0014976B1 (enExample) |
| JP (1) | JPS55113760A (enExample) |
| AR (1) | AR223863A1 (enExample) |
| AT (1) | ATE818T1 (enExample) |
| AU (1) | AU529982B2 (enExample) |
| CA (1) | CA1148962A (enExample) |
| CS (1) | CS208798B2 (enExample) |
| DD (1) | DD148772A5 (enExample) |
| DE (2) | DE2906603A1 (enExample) |
| ES (1) | ES488656A1 (enExample) |
| FI (1) | FI70702C (enExample) |
| HU (1) | HU182801B (enExample) |
| IE (1) | IE49267B1 (enExample) |
| IL (1) | IL59425A (enExample) |
| PL (1) | PL129707B1 (enExample) |
| PT (1) | PT70847A (enExample) |
| SU (1) | SU1181541A3 (enExample) |
| ZA (1) | ZA80902B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4925835A (en) * | 1986-05-01 | 1990-05-15 | Sloan-Kettering Institute For Cancer Research | Aziridinyl putrescine containing compositions and their uses in treating prostate cancer |
| JPH07301287A (ja) * | 1995-03-23 | 1995-11-14 | Sumitomo Heavy Ind Ltd | 制御装置に用いられる内接噛合遊星歯車機構 |
| AU8171498A (en) | 1997-06-27 | 1999-01-19 | Arizona Board Of Regents On Behalf Of The University Of Arizona, The | Novel cyanoaziridines for treating cancer |
| WO2002041871A2 (en) * | 2000-11-21 | 2002-05-30 | Board Of Regents, The University Of Texas System | Composition comprising an imexon or derivatives thereof and lipids |
| US20030129222A1 (en) * | 2000-11-21 | 2003-07-10 | Gabriel Lopez-Berestein | Liposomal imexon |
| ES2294197T3 (es) * | 2001-12-21 | 2008-04-01 | Supernus Pharmaceuticals, Inc. | Formulacion de capsula oral con estabilidad fisica aumentada. |
| US20040005339A1 (en) * | 2002-06-28 | 2004-01-08 | Shojaei Amir H. | Formulations of fenofibrate and/or fenofibrate derivatives with improved oral bioavailability |
| GEP20084540B (en) | 2003-01-14 | 2008-11-25 | Arena Pharm Inc | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| MXPA05007614A (es) * | 2003-02-24 | 2006-05-25 | Arena Pharm Inc | Derivados de fenilo y piridilpiperidina como moduladores del metabolismo de glucosa. |
| AR045047A1 (es) | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| EP1756084B1 (en) * | 2004-06-04 | 2008-11-26 | Arena Pharmaceuticals, Inc. | Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
| DOP2006000010A (es) | 2005-01-10 | 2006-07-31 | Arena Pharm Inc | Procedimiento para preparar eteres aromáticos |
| WO2007035355A2 (en) * | 2005-09-16 | 2007-03-29 | Arena Pharmaceuticals, Inc. | Modulators of metabolism and the treatment of disorders related thereto |
| TW200811147A (en) * | 2006-07-06 | 2008-03-01 | Arena Pharm Inc | Modulators of metabolism and the treatment of disorders related thereto |
| TW200811140A (en) * | 2006-07-06 | 2008-03-01 | Arena Pharm Inc | Modulators of metabolism and the treatment of disorders related thereto |
| US8853419B2 (en) | 2010-01-27 | 2014-10-07 | Arena Pharmaceuticals, Inc. | Processes for the preparation of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
| JP5941916B2 (ja) | 2010-09-22 | 2016-06-29 | アリーナ ファーマシューティカルズ， インコーポレイテッド | Ｇｐｒ１１９レセプターのモジュレーターおよびそれに関連する障害の処置 |
| DK3242666T5 (da) | 2015-01-06 | 2025-01-20 | Arena Pharm Inc | Forbindelsee til anvendelse i behandling af tilstande, der er forbundet med SIP1-receptoren |
| JP6838744B2 (ja) | 2015-06-22 | 2021-03-03 | アリーナ ファーマシューティカルズ， インコーポレイテッド | Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩 |
| KR20190116416A (ko) | 2017-02-16 | 2019-10-14 | 아레나 파마슈티칼스, 인크. | 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법 |
| ES2987794T3 (es) | 2018-06-06 | 2024-11-18 | Arena Pharm Inc | Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1 |
| CN113816887A (zh) * | 2021-08-31 | 2021-12-21 | 华中科技大学 | 一种氮杂环丙烷类化合物及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2644820A1 (de) * | 1976-10-05 | 1978-04-06 | Boehringer Mannheim Gmbh | Cancerostatisch und immunstimulierend wirkende 1-(n-acyl-carbamoyl)-2-cyanaziridine sowie verfahren zur herstellung derselben |
| DE2731264A1 (de) | 1977-07-11 | 1979-02-01 | Boehringer Mannheim Gmbh | Neue 1-acyl-2-cyanaziridine, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zubereitungen |
-
1979
- 1979-02-21 DE DE19792906603 patent/DE2906603A1/de not_active Withdrawn
-
1980
- 1980-02-15 ES ES488656A patent/ES488656A1/es not_active Expired
- 1980-02-16 EP EP80100792A patent/EP0014976B1/de not_active Expired
- 1980-02-16 DE DE8080100792T patent/DE3060268D1/de not_active Expired
- 1980-02-16 AT AT80100792T patent/ATE818T1/de not_active IP Right Cessation
- 1980-02-18 PL PL1980222088A patent/PL129707B1/pl unknown
- 1980-02-18 AU AU55649/80A patent/AU529982B2/en not_active Ceased
- 1980-02-18 ZA ZA00800902A patent/ZA80902B/xx unknown
- 1980-02-18 SU SU802882348A patent/SU1181541A3/ru active
- 1980-02-18 CA CA000345886A patent/CA1148962A/en not_active Expired
- 1980-02-19 DD DD80219137A patent/DD148772A5/de not_active IP Right Cessation
- 1980-02-19 HU HU80383A patent/HU182801B/hu not_active IP Right Cessation
- 1980-02-19 IL IL59425A patent/IL59425A/xx unknown
- 1980-02-19 CS CS801134A patent/CS208798B2/cs unknown
- 1980-02-20 FI FI800510A patent/FI70702C/fi not_active IP Right Cessation
- 1980-02-20 PT PT70847A patent/PT70847A/pt unknown
- 1980-02-20 IE IE327/80A patent/IE49267B1/en unknown
- 1980-02-21 JP JP1977580A patent/JPS55113760A/ja active Granted
-
1981
- 1981-02-15 AR AR279976A patent/AR223863A1/es active
- 1981-02-20 US US06/236,375 patent/US4397848A/en not_active Expired - Fee Related
-
1983
- 1983-05-17 US US06/495,548 patent/US4517183A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA1148962A (en) | 1983-06-28 |
| ZA80902B (en) | 1981-03-25 |
| SU1181541A3 (ru) | 1985-09-23 |
| PL129707B1 (en) | 1984-06-30 |
| FI70702B (fi) | 1986-06-26 |
| HU182801B (en) | 1984-03-28 |
| DE3060268D1 (en) | 1982-05-19 |
| IL59425A0 (en) | 1980-05-30 |
| IE49267B1 (en) | 1985-09-04 |
| IL59425A (en) | 1984-05-31 |
| DD148772A5 (de) | 1981-06-10 |
| AU529982B2 (en) | 1983-06-30 |
| FI70702C (fi) | 1986-10-06 |
| JPS55113760A (en) | 1980-09-02 |
| EP0014976A1 (de) | 1980-09-03 |
| US4397848A (en) | 1983-08-09 |
| PT70847A (de) | 1980-03-01 |
| CS208798B2 (en) | 1981-09-15 |
| ATE818T1 (de) | 1982-04-15 |
| DE2906603A1 (de) | 1980-09-04 |
| PL222088A1 (enExample) | 1980-12-01 |
| EP0014976B1 (de) | 1982-04-07 |
| ES488656A1 (es) | 1980-09-16 |
| US4517183A (en) | 1985-05-14 |
| IE800327L (en) | 1980-08-21 |
| FI800510A7 (fi) | 1980-08-22 |
| JPH0150700B2 (enExample) | 1989-10-31 |
| AU5564980A (en) | 1980-08-28 |
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