AR128559A1 - Procesos para la preparación de n-(1-metilciclopropil)-2-(3-piridinil)-2h-indazol-4-carboxamida e intermedios de la misma - Google Patents
Procesos para la preparación de n-(1-metilciclopropil)-2-(3-piridinil)-2h-indazol-4-carboxamida e intermedios de la mismaInfo
- Publication number
- AR128559A1 AR128559A1 ARP230100386A ARP230100386A AR128559A1 AR 128559 A1 AR128559 A1 AR 128559A1 AR P230100386 A ARP230100386 A AR P230100386A AR P230100386 A ARP230100386 A AR P230100386A AR 128559 A1 AR128559 A1 AR 128559A1
- Authority
- AR
- Argentina
- Prior art keywords
- compound
- reaction
- mixture
- reaction mixture
- scheme
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 13
- 238000002360 preparation method Methods 0.000 title abstract 8
- 150000001875 compounds Chemical class 0.000 abstract 47
- 239000011541 reaction mixture Substances 0.000 abstract 40
- 239000000203 mixture Substances 0.000 abstract 27
- 239000007795 chemical reaction product Substances 0.000 abstract 24
- 239000002904 solvent Substances 0.000 abstract 20
- 238000006243 chemical reaction Methods 0.000 abstract 19
- 239000002585 base Substances 0.000 abstract 11
- 239000000543 intermediate Substances 0.000 abstract 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- 239000003638 chemical reducing agent Substances 0.000 abstract 3
- 239000007800 oxidant agent Substances 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 101100006371 Arabidopsis thaliana CHX3 gene Proteins 0.000 abstract 2
- WNLDKUJBVKSZOA-UHFFFAOYSA-N CC1(CC1)NC(=O)C=1C2=CN(N=C2C=CC=1)C=1C=NC=CC=1 Chemical compound CC1(CC1)NC(=O)C=1C2=CN(N=C2C=CC=1)C=1C=NC=CC=1 WNLDKUJBVKSZOA-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 2
- 230000001590 oxidative effect Effects 0.000 abstract 2
- 239000003444 phase transfer catalyst Substances 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 229910001516 alkali metal iodide Inorganic materials 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 238000005660 chlorination reaction Methods 0.000 abstract 1
- NEHMKBQYUWJMIP-UHFFFAOYSA-N chloromethane Chemical compound ClC NEHMKBQYUWJMIP-UHFFFAOYSA-N 0.000 abstract 1
- -1 ethyl magnesium halide Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 239000011941 photocatalyst Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000010936 titanium Substances 0.000 abstract 1
- 229910052719 titanium Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P3/00—Fungicides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/44—Palladium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
- B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
- B01J31/0235—Nitrogen containing compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
- B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
- B01J31/0235—Nitrogen containing compounds
- B01J31/0244—Nitrogen containing compounds with nitrogen contained as ring member in aromatic compounds or moieties, e.g. pyridine
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
- B01J31/2208—Oxygen, e.g. acetylacetonates
- B01J31/2226—Anionic ligands, i.e. the overall ligand carries at least one formal negative charge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
- C07C209/28—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with other reducing agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/46—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of carboxylic acids or esters thereof in presence of ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/50—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/58—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/04—Saturated compounds having a carboxyl group bound to a three or four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/60—Reduction reactions, e.g. hydrogenation
- B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/82—Metals of the platinum group
- B01J2531/824—Palladium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Materials Engineering (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Insects & Arthropods (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263311276P | 2022-02-17 | 2022-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR128559A1 true AR128559A1 (es) | 2024-05-22 |
Family
ID=85641082
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP230100386A AR128559A1 (es) | 2022-02-17 | 2023-02-17 | Procesos para la preparación de n-(1-metilciclopropil)-2-(3-piridinil)-2h-indazol-4-carboxamida e intermedios de la misma |
| ARP230100384A AR128557A1 (es) | 2022-02-17 | 2023-02-17 | Procesos para la preparación de n-(1-metilciclopropil)-2-(3-piridinil)-2h-indazol-4-carboxamida e intermedios de la misma |
| ARP230100388A AR128561A1 (es) | 2022-02-17 | 2023-02-17 | Procesos para la preparación de n-(1-metilciclopropil)-2-(3-piridinil)-2h-indazol-4-carboxamida e intermedios de la misma |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP230100384A AR128557A1 (es) | 2022-02-17 | 2023-02-17 | Procesos para la preparación de n-(1-metilciclopropil)-2-(3-piridinil)-2h-indazol-4-carboxamida e intermedios de la misma |
| ARP230100388A AR128561A1 (es) | 2022-02-17 | 2023-02-17 | Procesos para la preparación de n-(1-metilciclopropil)-2-(3-piridinil)-2h-indazol-4-carboxamida e intermedios de la misma |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20250154124A1 (enExample) |
| EP (3) | EP4479393A1 (enExample) |
| JP (3) | JP2025507561A (enExample) |
| KR (3) | KR20240152343A (enExample) |
| CN (3) | CN118715212A (enExample) |
| AR (3) | AR128559A1 (enExample) |
| AU (3) | AU2023222774A1 (enExample) |
| IL (3) | IL314592A (enExample) |
| MX (3) | MX2024010071A (enExample) |
| PY (3) | PY2311482A (enExample) |
| TW (3) | TW202342445A (enExample) |
| UY (3) | UY40152A (enExample) |
| WO (3) | WO2023158770A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN122301706A (zh) * | 2026-06-01 | 2026-06-30 | 福安药业集团重庆博圣制药有限公司 | 盐酸氯普鲁卡因及其中间体的制备方法与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI652014B (zh) | 2013-09-13 | 2019-03-01 | 美商艾佛艾姆希公司 | 雜環取代之雙環唑殺蟲劑 |
| CN107635984B (zh) * | 2015-03-11 | 2021-04-13 | Fmc公司 | 杂环取代的二环唑杀有害生物剂 |
| KR102536024B1 (ko) * | 2015-03-12 | 2023-05-24 | 에프엠씨 코포레이션 | 헤테로환-치환 이환 아졸 살충제 |
| TWI873157B (zh) * | 2019-07-11 | 2025-02-21 | 美商富曼西公司 | 包含吲唑之殺蟲混合物 |
| CN111349111A (zh) * | 2020-03-23 | 2020-06-30 | 安徽省逸欣铭医药科技有限公司 | 一种喷他佐辛前药、其制备方法及其用途 |
-
2023
- 2023-02-06 TW TW112104076A patent/TW202342445A/zh unknown
- 2023-02-06 TW TW112104067A patent/TW202342438A/zh unknown
- 2023-02-13 TW TW112104943A patent/TW202344496A/zh unknown
- 2023-02-17 AR ARP230100386A patent/AR128559A1/es unknown
- 2023-02-17 IL IL314592A patent/IL314592A/en unknown
- 2023-02-17 IL IL314647A patent/IL314647A/en unknown
- 2023-02-17 IL IL314649A patent/IL314649A/en unknown
- 2023-02-17 AU AU2023222774A patent/AU2023222774A1/en active Pending
- 2023-02-17 EP EP23711266.9A patent/EP4479393A1/en not_active Withdrawn
- 2023-02-17 EP EP23711268.5A patent/EP4479395A1/en not_active Withdrawn
- 2023-02-17 CN CN202380022264.4A patent/CN118715212A/zh active Pending
- 2023-02-17 WO PCT/US2023/013267 patent/WO2023158770A1/en not_active Ceased
- 2023-02-17 US US18/838,863 patent/US20250154124A1/en active Pending
- 2023-02-17 AR ARP230100384A patent/AR128557A1/es unknown
- 2023-02-17 AU AU2023221271A patent/AU2023221271A1/en active Pending
- 2023-02-17 CN CN202380022266.3A patent/CN118715213A/zh active Pending
- 2023-02-17 UY UY0001040152A patent/UY40152A/es unknown
- 2023-02-17 PY PY202302311482A patent/PY2311482A/es unknown
- 2023-02-17 WO PCT/US2023/013268 patent/WO2023158771A1/en not_active Ceased
- 2023-02-17 JP JP2024548365A patent/JP2025507561A/ja active Pending
- 2023-02-17 US US18/839,255 patent/US20250163010A1/en active Pending
- 2023-02-17 KR KR1020247030591A patent/KR20240152343A/ko active Pending
- 2023-02-17 UY UY0001040150A patent/UY40150A/es unknown
- 2023-02-17 JP JP2024548366A patent/JP2025507562A/ja active Pending
- 2023-02-17 AU AU2023220077A patent/AU2023220077A1/en active Pending
- 2023-02-17 US US18/839,283 patent/US20250179043A1/en active Pending
- 2023-02-17 AR ARP230100388A patent/AR128561A1/es unknown
- 2023-02-17 PY PY202302311479A patent/PY2311479A/es unknown
- 2023-02-17 WO PCT/US2023/013266 patent/WO2023158769A1/en not_active Ceased
- 2023-02-17 MX MX2024010071A patent/MX2024010071A/es unknown
- 2023-02-17 CN CN202380021091.4A patent/CN118679154A/zh active Pending
- 2023-02-17 KR KR1020247030594A patent/KR20240152344A/ko active Pending
- 2023-02-17 JP JP2024548364A patent/JP2025507560A/ja active Pending
- 2023-02-17 KR KR1020247030595A patent/KR20240152345A/ko active Pending
- 2023-02-17 PY PY202302311474A patent/PY2311474A/es unknown
- 2023-02-17 MX MX2024010029A patent/MX2024010029A/es unknown
- 2023-02-17 UY UY0001040151A patent/UY40151A/es unknown
- 2023-02-17 MX MX2024010028A patent/MX2024010028A/es unknown
- 2023-02-17 EP EP23711267.7A patent/EP4479394A1/en not_active Withdrawn
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Zhu et al. | Recent advances in the direct β-C (sp2)–H functionalization of enamides | |
| Sun et al. | Recent advances in three-component radical acylative difunctionalization of unsaturated carbon–carbon bonds | |
| Sauer et al. | An electrocatalytic approach to the radical difunctionalization of alkenes | |
| Jiang et al. | Facile one-pot synthesis of sulfonyl fluorides from sulfonates or sulfonic acids | |
| US3996259A (en) | Oxidation of organic compounds by aqueous hypohalites using phase transfer catalysis | |
| WO2011154953A1 (en) | Process for the preparation of iodides | |
| US20040077901A1 (en) | Process for the synthesis of trifluorophenylacetic acids | |
| HU226938B1 (en) | Method for preparing substituted benzyl bromides | |
| Vafaeezadeh et al. | The possibilities of palladium-catalyzed aromatic cyanation in aqueous media | |
| Ma et al. | An efficient new methodology for the synthesis of 1-functionalized 2-halo-2-alkenes via hydrohalogenation reaction of electron-deficient allenes | |
| Carbone et al. | A catalytic and tert-butoxide ion-mediated amidation of aldehydes with para-nitro azides | |
| JP2006316034A (ja) | ジオレフィン化合物の選択酸化による２官能性エポキシモノマーの製造方法 | |
| JP5709654B2 (ja) | ポリクロロプロペンの製造方法 | |
| AR128557A1 (es) | Procesos para la preparación de n-(1-metilciclopropil)-2-(3-piridinil)-2h-indazol-4-carboxamida e intermedios de la misma | |
| JPS61271255A (ja) | アニリン類の製造方法 | |
| JP2010155805A (ja) | エポキシ化合物の製造方法 | |
| JPH06234668A (ja) | ９，９−ジアルキルフルオレンの製造方法 | |
| SK50332005A3 (sk) | Spôsob výroby 4-(4-fluórfenyl)-6-izopropyl-2-(N-metyl-N- metylsulfonyl-amino)-5-pyrimidínkarbaldehydu a jeho použitie | |
| JP2993877B2 (ja) | 含ハロゲン芳香族ニトリル化合物の製造方法 | |
| TWI280963B (en) | Manufacture method for penicillanic acid compounds | |
| RU2243213C2 (ru) | Способ получения 4,4`-азобис-(4-цианпентановой кислоты) | |
| CN110294686B (zh) | α-酮酰胺的绿色制备方法 | |
| SK1612000A3 (en) | Process for the preparation of esters of cyanoacetic acid | |
| CN1720229A (zh) | 光化学卤化方法 | |
| Lu et al. | O-alkylation of disodium salt of diethyl 3, 4-dihydroxythiophene-2, 5-dicarboxylate with 1, 2-dichloroethane catalyzed by ionic type phase transfer catalyst and potassium iodide |