AR115699A1 - Tiofenocarboxamidas sustituidas y análogos de las mismas - Google Patents

Tiofenocarboxamidas sustituidas y análogos de las mismas

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Publication number
AR115699A1
AR115699A1 ARP190101891A ARP190101891A AR115699A1 AR 115699 A1 AR115699 A1 AR 115699A1 AR P190101891 A ARP190101891 A AR P190101891A AR P190101891 A ARP190101891 A AR P190101891A AR 115699 A1 AR115699 A1 AR 115699A1
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AR
Argentina
Prior art keywords
alkyl
hydrogen atom
aralkyl
cyclopropyl
group
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ARP190101891A
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English (en)
Inventor
Tomoki Tsuchiya
Lionel Nicolas
Thomas Knobloch
Jrmy Dufour
Pierre Coqueron
- Brunet Stphane Yves
David Bernier
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Bayer Ag
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Publication of AR115699A1 publication Critical patent/AR115699A1/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/10Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with sulfur as the ring hetero atom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/26Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
    • A01N43/28Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/761,3-Oxazoles; Hydrogenated 1,3-oxazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P1/00Disinfectants; Antimicrobial compounds or mixtures thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P13/00Herbicides; Algicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/0825Preparations of compounds not comprising Si-Si or Si-cyano linkages
    • C07F7/083Syntheses without formation of a Si-C bond

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

Tiofenocarboxamidas y análogos de las mismas que se pueden usar para la protección de cultivos de enfermedades bacterianas, en particular contra enfermedades bacterianas causadas por bacterias pertenecientes al género Xanthomonas. Reivindicación 1: Un compuesto caracterizado porque es de fórmula (1), donde R¹, R² y R³ son un átomo de cloro; R⁴ se selecciona entre el grupo que consiste en átomo de hidrógeno, 2-metilpropilo, 1-metilpropilo, ciclopropilo, ciclopropilo sustituido con C₂₋₆-alquenilo, aralquilo y aralquilo sustituido con hidroxilo y R⁵ es un átomo de hidrógeno; o R⁴ y R⁵ forman junto con el átomo de carbono al cual están unidos un ciclopropilo; R⁶ se selecciona entre el grupo que consiste en átomo de hidrógeno, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-cianoalquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₈-cicloalquilo, arilo, aralquilo, -C₁₋₆-alquil-Si(C₁₋₆-alquil)₃ y -C₁₋₆-alquil-C₃₋₈-cicloalquilo; R⁷ es un átomo de hidrógeno o un C₁₋₆-alquilo. Reivindicación 11: Un compuesto caracterizado porque es de fórmula (2) ó (3), donde R¹, R², R³ son un átomo de cloro; R⁴ se selecciona entre el grupo que consiste en átomo de hidrógeno, 2-metilpropilo, 1-metilpropilo, ciclopropilo, ciclopropilo sustituido con C₂₋₆-alquenilo, aralquilo y aralquilo sustituido con hidroxilo y R⁵ es un átomo de hidrógeno; o R⁴ y R⁵ forman junto con el átomo de carbono al cual están unidos un ciclopropilo; R⁶ se selecciona entre el grupo que consiste en átomo de hidrógeno, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-cianoalquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₈-cicloalquilo, arilo, aralquilo, -C₁₋₆-alquil-Si(C₁₋₆-alquil)₃ y -C₁₋₆-alquil-C₃₋₈-cicloalquilo. Reivindicación 12: Un compuesto caracterizado porque es de fórmula (4), donde R¹, R², R³ son un átomo de cloro; R⁴ se selecciona entre el grupo que consiste en átomo de hidrógeno, 2-metilpropilo, 1-metilpropilo, ciclopropilo, ciclopropilo sustituido con C₂₋₆-alquenilo, aralquilo y aralquilo sustituido con hidroxilo y R⁵ es un átomo de hidrógeno; o R⁴ y R⁵ forman junto con el átomo de carbono al cual están unidos un ciclopropilo; R⁶ se selecciona entre el grupo que consiste en átomo de hidrógeno, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-cianoalquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₈-cicloalquilo, arilo, aralquilo, -C₁₋₆-alquil-Si(C₁₋₆-alquil)₃ y -C₁₋₆-alquil-C₃₋₈-cicloalquilo; con la condición de que el compuesto de fórmula (4) no representa: N-[(4,5-dicloro-2-tienil)carbonil]glicina [138326-45-1], N-[(4,5-dicloro-2-tienil)carbonil]isoleucina [138326-47-3], N-[(4,5-dicloro-2-tienil)carbonil]leucina [138326-54-2], N-[(4,5-dicloro-2-tienil)carbonil]leucinato de metilo [138326-32-6], N-[(4,5-dicloro-2-tienil)carbonil]isoleucinato de metilo [138326-33-7], N-[(4,5-dicloro-2-tienil)carbonil]valinato de 2,2,2-trifluoroetilo [138326-35-9], N-[(4,5-dicloro-2-tienil)carbonil]leucinato de 2,2,2-trifluoroetilo [138326-36-0], y N-[(4,5-dicloro-2-tienil)carbonil]isoleucinato de 2,2,2-trifluoroetilo [138326-37-1]. Reivindicación 13: Un compuesto caracterizado porque es de fórmula (5), (6) ó (7), donde R¹, R², R³ son un átomo de cloro; R⁴ se selecciona entre el grupo que consiste en átomo de hidrógeno, 2-metilpropilo, 1-metilpropilo, ciclopropilo, ciclopropilo sustituido con C₂₋₆-alquenilo, aralquilo y aralquilo sustituido con hidroxilo y R⁵ es un átomo de hidrógeno; o R⁴ y R⁵ forman junto con el átomo de carbono al cual están unidos un ciclopropilo; R⁶ se selecciona entre el grupo que consiste en átomo de hidrógeno, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-cianoalquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₈-cicloalquilo, arilo, aralquilo, -C₁₋₆-alquil-Si(C₁₋₆-alquil)₃ y -C₁₋₆-alquil-C₃₋₈-cicloalquilo; donde R⁴ se selecciona entre el grupo que consiste en átomo de hidrógeno, C₁₋₆-alquilo, aralquilo, aralquilo sustituido con hidroxilo, C₁₋₆-alquilo sustituido con un C₁₋₆-alquilsulfanilo y R⁵ es un átomo de hidrógeno cuando R⁶ es un átomo de hidrógeno o C₁₋₆-alquilo.
ARP190101891A 2018-07-05 2019-07-03 Tiofenocarboxamidas sustituidas y análogos de las mismas AR115699A1 (es)

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EP18181930 2018-07-05

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ARP190101891A AR115699A1 (es) 2018-07-05 2019-07-03 Tiofenocarboxamidas sustituidas y análogos de las mismas
ARP190101890A AR115698A1 (es) 2018-07-05 2019-07-03 Tieniloxazolonas y análogos de las mismas
ARP190101889A AR115697A1 (es) 2018-07-05 2019-07-03 Tiofenocarboxamidas sustituidas y análogos de las mismas

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ARP190101890A AR115698A1 (es) 2018-07-05 2019-07-03 Tieniloxazolonas y análogos de las mismas
ARP190101889A AR115697A1 (es) 2018-07-05 2019-07-03 Tiofenocarboxamidas sustituidas y análogos de las mismas

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US (4) US11401254B2 (es)
EP (3) EP3818050B1 (es)
JP (3) JP7476118B2 (es)
KR (3) KR20210031476A (es)
CN (3) CN112638893B (es)
AR (3) AR115699A1 (es)
AU (3) AU2019297401B2 (es)
BR (3) BR112020026929A2 (es)
CA (3) CA3105407A1 (es)
CL (3) CL2020003442A1 (es)
CO (3) CO2020016675A2 (es)
CR (3) CR20200640A (es)
EC (3) ECSP20084373A (es)
ES (3) ES2928908T3 (es)
HU (2) HUE060281T2 (es)
MA (3) MA53089B1 (es)
MX (3) MX2021000031A (es)
PE (3) PE20210138A1 (es)
PH (3) PH12021550014A1 (es)
PL (3) PL3818049T3 (es)
PT (3) PT3818051T (es)
TW (3) TWI823960B (es)
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