AR112818A1 - Fabricación de composiciones farmacéuticas que comprenden uno o más de estos: un péptido, una proteína y un anticuerpo - Google Patents
Fabricación de composiciones farmacéuticas que comprenden uno o más de estos: un péptido, una proteína y un anticuerpoInfo
- Publication number
- AR112818A1 AR112818A1 ARP180102646A ARP180102646A AR112818A1 AR 112818 A1 AR112818 A1 AR 112818A1 AR P180102646 A ARP180102646 A AR P180102646A AR P180102646 A ARP180102646 A AR P180102646A AR 112818 A1 AR112818 A1 AR 112818A1
- Authority
- AR
- Argentina
- Prior art keywords
- manufacture
- peptide
- antibody
- protein
- pharmaceutical compositions
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/02—Maintaining the aggregation state of the mixed materials
- B01F23/024—Maintaining mixed ingredients in movement to prevent separation of the ingredients after mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/05—Stirrers
- B01F27/11—Stirrers characterised by the configuration of the stirrers
- B01F27/114—Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections
- B01F27/1143—Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections screw-shaped, e.g. worms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/60—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis
- B01F27/72—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis with helices or sections of helices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/82—Combinations of dissimilar mixers
- B01F33/821—Combinations of dissimilar mixers with consecutive receptacles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/84—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2111—Flow rate
- B01F35/21111—Mass flow rate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/2132—Concentration, pH, pOH, p(ION) or oxygen-demand
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/214—Measuring characterised by the means for measuring
- B01F35/2144—Measuring characterised by the means for measuring using radiation for measuring the parameters of the mixture or components to be mixed
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/22—Control or regulation
- B01F35/2201—Control or regulation characterised by the type of control technique used
- B01F35/2203—Controlling the mixing process by feed-forward, i.e. a parameter of the components to be mixed is measured and the feed values are calculated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/715—Feeding the components in several steps, e.g. successive steps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/80—Forming a predetermined ratio of the substances to be mixed
- B01F35/82—Forming a predetermined ratio of the substances to be mixed by adding a material to be mixed to a mixture in response to a detected feature, e.g. density, radioactivity, consumed power or colour
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/06—Mixing phases by adding a very small quantity of one of the phases or microdosing
- B01F23/062—Mixing ingredients in very small quantity, adding microingredients or microconcentration, e.g. adding vitamins, minerals, proteins, enzymes, hormones, antibiotics or worm medicines
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2117—Weight
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/2135—Humidity, e.g. moisture content
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente descripción divulga un procedimiento para la fabricación continua de una composición farmacéutica líquida, procedimiento que comprende proporcionar una unidad de mezclado, alimentar un agente terapéutico y un vehículo líquido en la unidad de mezclado, hacer funcionar esta última para que se mezcle el agente y el vehículo en una composición farmacéutica líquida, descargar la composición en una unidad de retención.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17191652 | 2017-09-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR112818A1 true AR112818A1 (es) | 2019-12-18 |
Family
ID=59914324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP180102646A AR112818A1 (es) | 2017-09-18 | 2018-09-18 | Fabricación de composiciones farmacéuticas que comprenden uno o más de estos: un péptido, una proteína y un anticuerpo |
Country Status (22)
Country | Link |
---|---|
US (1) | US20200222319A1 (es) |
EP (1) | EP3684335A1 (es) |
JP (1) | JP7291127B2 (es) |
KR (1) | KR102586260B1 (es) |
CN (1) | CN111372571B (es) |
AR (1) | AR112818A1 (es) |
AU (1) | AU2018332076A1 (es) |
BR (1) | BR112020004952A2 (es) |
CA (1) | CA3075689A1 (es) |
CL (1) | CL2020000643A1 (es) |
CO (1) | CO2020002904A2 (es) |
EA (1) | EA039921B1 (es) |
IL (1) | IL273259A (es) |
JO (1) | JOP20200058A1 (es) |
MX (1) | MX2020002779A (es) |
PH (1) | PH12020500525A1 (es) |
SG (1) | SG11202002168SA (es) |
TN (1) | TN2020000047A1 (es) |
TW (1) | TWI775943B (es) |
UA (1) | UA127186C2 (es) |
WO (1) | WO2019053247A1 (es) |
ZA (1) | ZA202001544B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20220135868A1 (en) * | 2020-11-04 | 2022-05-05 | Saudi Arabian Oil Company | Methods and systems for the generation of stable oil-in-water or water-in-oil emulsion for enhanced oil recovery |
CN112569848B (zh) * | 2020-12-16 | 2022-11-15 | 安徽惠泽农业科技有限公司 | 一种多组份复合肥调制处理装置及复合肥生产工艺 |
US11583886B2 (en) * | 2021-03-15 | 2023-02-21 | The Boeing Company | Robot end effector with rotating barrel for dispensing an extrudable substance |
US11583876B2 (en) * | 2021-03-15 | 2023-02-21 | The Boeing Company | Positive displacement end effector with multiple cartridges |
US11850619B2 (en) * | 2021-03-15 | 2023-12-26 | The Boeing Company | Robot end effector for dispensing an extrudable substance |
WO2024076757A1 (en) * | 2022-10-07 | 2024-04-11 | Genzyme Corporation | Product formulation in biological manufacturing |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3034046A (en) * | 1959-10-12 | 1962-05-08 | Sasaki Shinichi | Automatic moisture content determination and control apparatus |
US3644826A (en) * | 1967-04-03 | 1972-02-22 | Industrial Nucleonics Corp | Moisture-measuring system using microwave and nucleonic measurements |
US5302394A (en) * | 1992-07-14 | 1994-04-12 | Mcneil-Ppc, Inc. | Dextromethorphan continuous lozenge manufacturing process |
KR100491522B1 (ko) * | 1996-06-03 | 2005-08-04 | 테트라 라발 홀딩즈 앤드 파이낸스 소시에떼 아노님 | 유동성제1액체를 한가지 이상의제2액체와 연속공정으로 혼합시키는 계량공급장치 |
SE506791C2 (sv) * | 1996-06-03 | 1998-02-09 | Arom Pak Ab | Doseringsanordning för att med ett kontinuerligt förfarande blanda en strömmande primärvätska med en eller flera tillförda sekundärvätskor samt sätt att sammanblanda två eller flera vätskor |
CN1251662C (zh) * | 2003-01-29 | 2006-04-19 | 中山大学 | 一种中药提取液的低温浓缩方法及其装置 |
US8271139B2 (en) | 2003-10-17 | 2012-09-18 | Asahi Kasei Bioprocess, Inc. | Multi-stage accurate blending system and method |
GB0416694D0 (en) * | 2004-07-27 | 2004-09-01 | Univ Strathclyde | Process for preparing microcrystals |
US8746959B2 (en) * | 2007-07-26 | 2014-06-10 | Ganado Technologies Corp. | Apparatus and method to feed livestock |
US20110037185A1 (en) * | 2008-04-30 | 2011-02-17 | James Kowalski | Continuous process for making pharmaceutical compositions |
US9138693B2 (en) * | 2011-03-22 | 2015-09-22 | Salah M. Aouad | Automated high precision solution preparation apparatus |
DE102010037516B4 (de) * | 2010-09-14 | 2012-05-24 | Chocotech Gmbh | Verfahren und Vorrichtung zur energiesparenden Herstellung von Süßwarenmassen |
CN202777089U (zh) * | 2012-09-21 | 2013-03-13 | 南京中医药大学 | 一种中药多功能提取、精制、浓缩设备 |
CN105075457B (zh) * | 2014-05-05 | 2017-11-17 | 中国农业机械化科学研究院 | 一种种子包衣机及其种药协同在线控制装置和方法 |
CN105686032B (zh) * | 2016-01-20 | 2018-03-30 | 宜诺(天津)科技有限公司 | 一种荸荠包衣锅自动化联线生产的方法 |
PT109117B (pt) * | 2016-01-28 | 2019-02-01 | Hovione Farm Sa | Complexação de ingredientes ativos farmacêuticos |
WO2017155669A1 (en) * | 2016-03-11 | 2017-09-14 | Fujifilm Planar Solutions, LLC | Advanced fluid processing methods and systems |
-
2018
- 2018-09-17 BR BR112020004952-2A patent/BR112020004952A2/pt unknown
- 2018-09-17 EP EP18770020.8A patent/EP3684335A1/en active Pending
- 2018-09-17 TW TW107132696A patent/TWI775943B/zh active
- 2018-09-17 CN CN201880074151.8A patent/CN111372571B/zh active Active
- 2018-09-17 WO PCT/EP2018/075034 patent/WO2019053247A1/en unknown
- 2018-09-17 EA EA202090508A patent/EA039921B1/ru unknown
- 2018-09-17 TN TNP/2020/000047A patent/TN2020000047A1/en unknown
- 2018-09-17 JP JP2020515736A patent/JP7291127B2/ja active Active
- 2018-09-17 AU AU2018332076A patent/AU2018332076A1/en active Pending
- 2018-09-17 KR KR1020207010134A patent/KR102586260B1/ko active IP Right Grant
- 2018-09-17 CA CA3075689A patent/CA3075689A1/en active Pending
- 2018-09-17 MX MX2020002779A patent/MX2020002779A/es unknown
- 2018-09-17 US US16/648,372 patent/US20200222319A1/en active Pending
- 2018-09-17 SG SG11202002168SA patent/SG11202002168SA/en unknown
- 2018-09-17 UA UAA202001748A patent/UA127186C2/uk unknown
- 2018-09-18 AR ARP180102646A patent/AR112818A1/es unknown
-
2019
- 2019-03-18 JO JOP/2020/0058A patent/JOP20200058A1/ar unknown
-
2020
- 2020-03-11 ZA ZA2020/01544A patent/ZA202001544B/en unknown
- 2020-03-12 CL CL2020000643A patent/CL2020000643A1/es unknown
- 2020-03-12 IL IL273259A patent/IL273259A/en unknown
- 2020-03-12 CO CONC2020/0002904A patent/CO2020002904A2/es unknown
- 2020-03-13 PH PH12020500525A patent/PH12020500525A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CO2020002904A2 (es) | 2020-05-29 |
ZA202001544B (en) | 2021-10-27 |
AU2018332076A1 (en) | 2020-04-02 |
JP7291127B2 (ja) | 2023-06-14 |
TW201919557A (zh) | 2019-06-01 |
EA039921B1 (ru) | 2022-03-28 |
BR112020004952A2 (pt) | 2020-09-15 |
CN111372571A (zh) | 2020-07-03 |
MX2020002779A (es) | 2020-11-06 |
CN111372571B (zh) | 2022-11-18 |
JP2020534288A (ja) | 2020-11-26 |
WO2019053247A1 (en) | 2019-03-21 |
PH12020500525A1 (en) | 2021-05-10 |
TN2020000047A1 (en) | 2021-10-04 |
EA202090508A1 (ru) | 2020-07-06 |
KR102586260B1 (ko) | 2023-10-06 |
TWI775943B (zh) | 2022-09-01 |
SG11202002168SA (en) | 2020-04-29 |
CA3075689A1 (en) | 2019-03-21 |
KR20200065002A (ko) | 2020-06-08 |
JOP20200058A1 (ar) | 2020-03-11 |
EP3684335A1 (en) | 2020-07-29 |
IL273259A (en) | 2020-04-30 |
US20200222319A1 (en) | 2020-07-16 |
CL2020000643A1 (es) | 2020-09-11 |
UA127186C2 (uk) | 2023-05-31 |
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