AR111434A2 - Material granular, cápsula resistente al agua, comprimido compactado de material granular, proceso para preparar el material granular y usos - Google Patents

Material granular, cápsula resistente al agua, comprimido compactado de material granular, proceso para preparar el material granular y usos

Info

Publication number
AR111434A2
AR111434A2 ARP180101098A ARP180101098A AR111434A2 AR 111434 A2 AR111434 A2 AR 111434A2 AR P180101098 A ARP180101098 A AR P180101098A AR P180101098 A ARP180101098 A AR P180101098A AR 111434 A2 AR111434 A2 AR 111434A2
Authority
AR
Argentina
Prior art keywords
granular material
weight
water
weight based
iii
Prior art date
Application number
ARP180101098A
Other languages
English (en)
Original Assignee
Cytochroma Dev Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytochroma Dev Inc filed Critical Cytochroma Dev Inc
Publication of AR111434A2 publication Critical patent/AR111434A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Iron (AREA)

Abstract

Un material granular que comprende (i) al menos 50% en peso en base al peso del material granular del compuesto metálico mixto inorgánico insoluble en agua sólido capaz de unir fosfato y que contiene hierro (III) y al menos uno de magnesio, calcio, lantano y cerio, donde el compuesto metálico mixto se selecciona del grupo formado por Mg₄Fe₂(OH)₁₂.CO₃.nH₂O, (ii) desde 3 hasta 10% en peso en base al peso del material granular de agua unida no químicamente, y (iii) no mas del 47% en peso en base al peso del material granular del excipiente; cápsula resistente al agua, comprimido compactado de material granular, proceso para preparar el material granular y usos. Reivindicación 1: Un material granular que comprende (i) al menos 50% en peso en base al peso del material granular del compuesto metálico mixto insoluble en agua sólido capaz de unir fosfato de la fórmula (1): MII₁₋ˣMIIIˣ(OH)₂Aⁿ⁻ʸ.zH₂O (1) donde MII es al menos uno de magnesio, calcio, lantano y cerio; MIII es al menos hierro (III); Aⁿ⁻ es al menos un anión n-valente; x = Sny; 0 < x £ 0,67; 0 < y £ 1; y 0 £ z £ 10; (ii) desde 3 hasta 12% en peso en base al peso del material granular de agua unida no químicamente; y (iii) no mas del 47% en peso en base al peso del material granular del excipiente. Reivindicación 7: Un material granular de acuerdo con cualquiera de las reivindicaciones 1 a 6 en donde el excipiente comprende al menos almidón pregelatinizado y crospovidona. Reivindicación 9: Una dosis unitaria para la administración oral que comprende una cápsula resistente al agua que contiene un material granular de acuerdo con cualquier reivindicación precedente. Reivindicación 12: Una dosis unitaria de acuerdo con la reivindicación 11 en donde el lubricante es o comprende estearato de magnesio. Reivindicación 14: Una dosis unitaria de acuerdo con la reivindicación 13 en donde el recubrimiento resistente al agua comprende al menos 30% en peso de un copolímero de metacrilato butilado.
ARP180101098A 2006-01-31 2018-04-27 Material granular, cápsula resistente al agua, comprimido compactado de material granular, proceso para preparar el material granular y usos AR111434A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0601899.8A GB0601899D0 (en) 2006-01-31 2006-01-31 Compositions

Publications (1)

Publication Number Publication Date
AR111434A2 true AR111434A2 (es) 2019-07-10

Family

ID=36061168

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180101098A AR111434A2 (es) 2006-01-31 2018-04-27 Material granular, cápsula resistente al agua, comprimido compactado de material granular, proceso para preparar el material granular y usos

Country Status (5)

Country Link
CN (1) CN101378730B (es)
AR (1) AR111434A2 (es)
GB (1) GB0601899D0 (es)
NO (1) NO345039B1 (es)
ZA (1) ZA200805903B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016029259A2 (pt) * 2014-06-18 2017-08-22 Unilever Nv hidróxido de dupla camada, composição de meios de filtro para purificação de água, método para produzir um hidróxido de dupla camada e uso do mesmo
CN104342123B (zh) * 2014-10-21 2016-02-24 淄博职业学院 能反映环境湿度的荧光薄膜材料及其制备方法
CN110191871A (zh) * 2017-01-20 2019-08-30 株式会社钟化 包含谷胱甘肽的粒状肥料

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69118886D1 (de) * 1990-06-08 1996-05-23 Commw Scient Ind Res Org Sorptionsmittel für ethylen
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
GB9720061D0 (en) * 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders

Also Published As

Publication number Publication date
NO345039B1 (no) 2020-08-31
CN101378730A (zh) 2009-03-04
CN101378730B (zh) 2014-07-09
NO20171980A1 (no) 2008-10-27
ZA200805903B (en) 2009-10-28
GB0601899D0 (en) 2006-03-08

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