AR066924A1 - Formulacion de nevirapina de liberacion prolongada - Google Patents

Formulacion de nevirapina de liberacion prolongada

Info

Publication number
AR066924A1
AR066924A1 ARP080102446A ARP080102446A AR066924A1 AR 066924 A1 AR066924 A1 AR 066924A1 AR P080102446 A ARP080102446 A AR P080102446A AR P080102446 A ARP080102446 A AR P080102446A AR 066924 A1 AR066924 A1 AR 066924A1
Authority
AR
Argentina
Prior art keywords
nevirapine
formulation
geometric mean
prolonged release
prolonged
Prior art date
Application number
ARP080102446A
Other languages
English (en)
Inventor
Michael Cappola
Svetiana Sienkiewicz
Hung Yu Cheng
Roger Charles Snow
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39739795&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR066924(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of AR066924A1 publication Critical patent/AR066924A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reivindicacion 1: Una composicion farmacéutica caracterizado porque: (a) comprende 300 mg de nevirapina en una matriz de liberacion prolongada y que, cuando se administra en forma de una dosis unica a un ser humano en ayunas, exhibe (1) una Cmax media geométrica de 1.000 a 2.300 ng/mL; y (2) una AUC0 media geométrica de 73.400 a 178.100 h(ng/mL); o (b) comprende 400 mg de nevirapina en una matriz de liberacion prolongada y que, cuando se administra en forma de una dosis unica a un ser humano en ayunas, exhibe (1) una Cmax media geométrica de 1.210 a 2.740 ng/mL; y (2) una AUC0 media geométrica de 109.000 a 237.000 h(ng/mL).
ARP080102446A 2007-06-08 2008-06-06 Formulacion de nevirapina de liberacion prolongada AR066924A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94276507P 2007-06-08 2007-06-08

Publications (1)

Publication Number Publication Date
AR066924A1 true AR066924A1 (es) 2009-09-23

Family

ID=39739795

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080102446A AR066924A1 (es) 2007-06-08 2008-06-06 Formulacion de nevirapina de liberacion prolongada

Country Status (29)

Country Link
US (1) US8460704B2 (es)
EP (1) EP2155169B1 (es)
JP (1) JP5417662B2 (es)
KR (1) KR101017862B1 (es)
CN (1) CN101784263B (es)
AR (1) AR066924A1 (es)
AU (1) AU2008262031B2 (es)
BR (1) BRPI0811732A2 (es)
CA (1) CA2687491C (es)
CL (1) CL2008001678A1 (es)
CO (1) CO6150128A2 (es)
DK (1) DK2155169T3 (es)
EA (1) EA018377B1 (es)
EC (1) ECSP099561A (es)
ES (1) ES2574836T3 (es)
HK (1) HK1145806A1 (es)
HU (1) HUE028598T2 (es)
IL (1) IL199924A0 (es)
MA (1) MA31430B1 (es)
MX (1) MX2009007764A (es)
NZ (1) NZ578664A (es)
PE (2) PE20131035A1 (es)
PL (1) PL2155169T3 (es)
TN (1) TN2009000510A1 (es)
TW (1) TWI419716B (es)
UA (1) UA97971C2 (es)
UY (1) UY31128A1 (es)
WO (1) WO2008154234A2 (es)
ZA (1) ZA200904939B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY149159A (en) 2005-11-15 2013-07-31 Hoffmann La Roche Method for treating joint damage
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
UA97971C2 (ru) 2007-06-08 2012-04-10 Берингер Ингельхайм Интернациональ Гмбх Препарат невирапина пролонгированного высвобождения
WO2009158704A2 (en) 2008-06-27 2009-12-30 Duke University Therapeutic agents comprising elastin-like peptides
US20140193491A1 (en) 2011-05-30 2014-07-10 Cipla Limited Pharmaceutical antiretroviral composition
US20130084277A1 (en) * 2011-08-24 2013-04-04 Phasebio Pharmaceuticals, Inc. Formulations of active agents for sustained release
CN104203244A (zh) * 2012-03-05 2014-12-10 希普拉有限公司 包含拉米夫定、festinnvir和奈韦拉平的抗反转录病毒药物组合物
CN104523630B (zh) * 2015-01-22 2017-08-25 山东新时代药业有限公司 一种奈韦拉平片剂
EP3153157A1 (en) 2015-10-09 2017-04-12 Teva Pharmaceutical Works Private Limited Company Pharmaceutical composition for prolonged release of nevirapine

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366972A (en) 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
CA2030056C (en) 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection
US5419917A (en) * 1994-02-14 1995-05-30 Andrx Pharmaceuticals, Inc. Controlled release hydrogel formulation
US6514530B2 (en) * 1997-09-09 2003-02-04 Alza Corporation Dosage form comprising means for changing drug delivery shape
PT1035834E (pt) 1997-12-05 2002-09-30 Alza Corp Forma de dosagem osmotica que compreende primeiro e segundo revestimentos
ES2213404T3 (es) * 1998-12-17 2004-08-16 Alza Corporation Transformacion de capsulas de gelatina rellenas de liquido en sistemas de liberacion controlada mediante multiples revestimientos.
EA005291B1 (ru) * 1999-03-31 2004-12-30 Янссен Фармацевтика Н.В. Применение предварительно желатинированного крахмала в композиции с контролируемым высвобождением
PT1225874E (pt) * 1999-09-24 2006-06-30 Janssen Pharmaceutica Nv Composicoes antivirais.
AU2084801A (en) 1999-12-09 2001-06-18 Alza Corporation Antiviral medication
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
WO2002092095A1 (en) 2001-05-11 2002-11-21 Boehringer Ingelheim International Gmbh Use of nevirapine to treat or prevent lipid pathology in patients with hiv that is resistant to nevirapine
US20030050620A1 (en) 2001-09-07 2003-03-13 Isa Odidi Combinatorial type controlled release drug delivery device
AU2003287666A1 (en) 2002-11-13 2004-06-03 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
CA2529852A1 (en) 2003-06-20 2004-12-29 Viral Genomix, Inc. Compositions for and methods for treating hiv
ES2286716T3 (es) 2003-10-01 2007-12-01 Lupin Limited Composicion farmaceutica de liberacion controlada y proceso para preparar la misma.
DK1696822T3 (da) 2003-11-13 2010-05-17 Psivida Inc Injicerbart vedvarende frigørelsesimplantat, som har en bioeroderbar matrixkerne og en bioeroderbar hus
PL1632232T6 (pl) * 2004-09-02 2022-06-27 Janssen Pharmaceutica Nv Sól 4-[[4-[[4-(2-cyjanoetenylo)-2,6-dimetylofenylo]amino]-2-pirymidynylo]amino]benzonitrylu
WO2006114709A1 (en) * 2005-04-25 2006-11-02 Aurobindo Pharma Limited Pharmaceutical compositions of antiretrovirals
AU2006263338A1 (en) 2005-06-29 2007-01-04 Panacea Biotec Ltd. Pharmaceutical sustained release compositions and processes thereof
US9198862B2 (en) * 2005-07-22 2015-12-01 Rubicon Research Private Limited Dispersible tablet composition
FR2891459B1 (fr) 2005-09-30 2007-12-28 Flamel Technologies Sa Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
JP2009511191A (ja) * 2005-10-14 2009-03-19 マイクロドース・テクノロジーズ・インコーポレーテッド 経口投与剤組合せ型医薬パッケージ法
UA97971C2 (ru) 2007-06-08 2012-04-10 Берингер Ингельхайм Интернациональ Гмбх Препарат невирапина пролонгированного высвобождения

Also Published As

Publication number Publication date
CA2687491C (en) 2011-09-20
AU2008262031A1 (en) 2008-12-18
AU2008262031B2 (en) 2011-08-25
CN101784263A (zh) 2010-07-21
CL2008001678A1 (es) 2009-09-11
BRPI0811732A2 (pt) 2014-11-18
MA31430B1 (fr) 2010-06-01
EA200900958A1 (ru) 2010-04-30
HK1145806A1 (en) 2011-05-06
EP2155169B1 (en) 2016-03-23
PL2155169T3 (pl) 2016-09-30
CN101784263B (zh) 2012-11-07
TN2009000510A1 (en) 2011-03-31
KR20100020447A (ko) 2010-02-22
TW200916127A (en) 2009-04-16
DK2155169T3 (en) 2016-06-13
PE20090371A1 (es) 2009-04-24
MX2009007764A (es) 2009-09-10
WO2008154234A9 (en) 2009-11-26
NZ578664A (en) 2011-11-25
WO2008154234A2 (en) 2008-12-18
EP2155169A2 (en) 2010-02-24
EA018377B1 (ru) 2013-07-30
ECSP099561A (es) 2009-09-29
CO6150128A2 (es) 2010-04-20
CA2687491A1 (en) 2008-12-18
UY31128A1 (es) 2009-01-30
JP5417662B2 (ja) 2014-02-19
HUE028598T2 (en) 2016-12-28
PE20131035A1 (es) 2013-10-01
ES2574836T3 (es) 2016-06-22
US8460704B2 (en) 2013-06-11
UA97971C2 (ru) 2012-04-10
TWI419716B (zh) 2013-12-21
JP2010520891A (ja) 2010-06-17
ZA200904939B (en) 2010-04-28
US20100278918A1 (en) 2010-11-04
IL199924A0 (en) 2010-04-15
KR101017862B1 (ko) 2011-03-04
WO2008154234A3 (en) 2010-01-21

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