AR110974A1 - Combinaciones de compuestos activos - Google Patents

Combinaciones de compuestos activos

Info

Publication number
AR110974A1
AR110974A1 ARP180100324A ARP180100324A AR110974A1 AR 110974 A1 AR110974 A1 AR 110974A1 AR P180100324 A ARP180100324 A AR P180100324A AR P180100324 A ARP180100324 A AR P180100324A AR 110974 A1 AR110974 A1 AR 110974A1
Authority
AR
Argentina
Prior art keywords
alkyl
phenyl
inhibitors
halogenoalkoxy
cycloalkyl
Prior art date
Application number
ARP180100324A
Other languages
English (en)
Inventor
Ricarda Miller
Pierre Coqueron
- Dr Ducrot Virginie Pascale Yves
Dahmen Peter Dr
Meissner Ruth Dr
Grtz Andreas Dr
Original Assignee
Bayer Ag
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Bayer Cropscience Ag filed Critical Bayer Ag
Publication of AR110974A1 publication Critical patent/AR110974A1/es

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/52—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing groups, e.g. carboxylic acid amidines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/26—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
    • A01N43/28—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
    • A01N43/30—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3 with two oxygen atoms in positions 1,3, condensed with a carbocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • A01N47/14—Di-thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/32—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing >N—CO—N< or >N—CS—N< groups directly attached to a cycloaliphatic ring

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Reivindicación 1: Combinación de principios activos caracterizada porque comprende (A) al menos un derivado de triazol de la fórmula [1], donde R¹ representa hidrógeno, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₈-cicloalquilo, C₃₋₈-cicloalquil-C₁₋₄-alquilo, fenilo, fenil-C₁₋₄-alquilo, fenil-C₂₋₄-alquenilo o fenil-C₂₋₄-alquinilo; R² representa hidrógeno, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₈-cicloalquilo, C₃₋₈-cicloalquil-C₁₋₄-alquilo, fenilo, fenil-C₁₋₄-alquilo, fenil-C₂₋₄-alquenilo o fenil-C₂₋₄-alquinilo, donde las fracciones alifáticas, sin incluir las fracciones de cicloalquilo, de R¹ y/o R² pueden transportar 1, 2, 3 o hasta la cantidad máxima posible de grupos idénticos o diferentes Rᵃ los cuales, uno independiente del otro, se seleccionan de halógeno, CN, nitro, fenilo, C₁₋₄-alcoxi y C₁₋₄-halógenoalcoxi, cuando el fenilo puede sustituirse por lo, 2, 3, 4 ó 5 sustituyentes seleccionados de halógeno, CN, nitro, C₁₋₄-alquilo, C₁₋₄-alcoxi, C₁₋₄-halógenoalquilo, C₁₋₄-halógenoalcoxi, y donde las fracciones cicloalquilo y/o fenilo de R¹ y/o R² pueden transportar 1, 2, 3, 4, 5 o hasta la cantidad máxima de grupos idénticos o diferentes Rᵇ los cuales, uno independiente del otro se seleccionan de halógeno, CN, nitro, C₁₋₄-alquilo, C₁₋₄-alcoxi, C₁₋₄-halógenoalquilo y C₁₋₄-halógenoalcoxi; cada R⁴ representa, uno independiente del otro, halógeno, CN, nitro, C₁₋₄-alquilo, C₁₋₄-halógenoalquilo, C₁₋₄-alcoxi, C₁₋₄-halógenoalcoxi, C₁₋₄-alquilcarbonilo, hidroxi-sustituido C₁₋₄-alquilo o pentafluoro-l⁶-sulfanilo; m es un número entero y es 0, 1, 2, 3, 4 ó 5; Y representa un heterociclo de 6 miembros que contiene 1 ó 2 átomo(s) de nitrógeno como heteroátomo(s) seleccionado(s) del grupo de fórmulas [2] donde Y está conectado a O de la fórmula [1] a través de las uniones identificados con “U” e Y está conectado a la fracción CR¹(OR²) de la fórmula [1] a través e las uniones identificadas como “V” y donde R representa hidrógeno, C₁₋₂-halógenoalquilo, C₁₋₂-halógenoalcoxi, C₁₋₂-alquilcarbonilo o halógeno; cada R³ representa, uno independiente del otro, halógeno, CN, nitro, C₁₋₄-alquilo, C₁₋₄-halógenoalquilo, C₁₋₄-alcoxi, C₁₋₄-halógenoalcoxi; n es un número entero y es 0, 1 ó 2; o su sal o N-óxido; y (B) al menos un compuesto activo adicional seleccionado de los siguientes grupos (1) inhibidores de la síntesis de ergosterol, (2) inhibidores de la cadena respiratoria en el complejo I o II, (3) inhibidores de la cadena respiratoria en el complejo III, (4) inhibidores de la mitosis y la división celular, (5) compuestos capaces de tener una acción múltiple, (6) compuestos capaces de inducir una defensa del huésped, (7) inhibidores de la biosíntesis de aminoácidos y/o de las proteínas, (8) inhibidores de la producción de ATP, (9) inhibidores de la síntesis de la pared celular, (10) inhibidores de la síntesis de los lípidos y de la membrana, (11) inhibidores de la biosíntesis de melanina, (12) inhibidores de la síntesis de ácidos nucleicos, (13) inhibidores de la transducción de señal, (14) compuestos capaces de actuar como desacople, (15) otros fungicidas. Reivindicación 7: La combinación de compuestos activos de acuerdo con al menos una de las reivindicaciones 1 a 6, caracterizada porque el derivado de triazol de la fórmula [1] se selecciona del grupo que consiste en (I.01) 2-[6-(4-clorofenoxi)-2-(trifluorometil)piridin-3-il]-1-(1H-1,2,4-triazol-1-il)propan-2-ol, (I.59) 2-[6-(4-bromofenoxi)-2-(trifluorometil)piridin-3-il]-1-(1H-1,2,4-triazol-1-il)propan-2-ol, (I.81) 1-[6-(4-bromofenoxi)-2-(trifluorometil)piridin-3-il]-1-ciclopropil-2-(1H-1,2,4-triazol-1-il)etanol y (I.91) 1-[6-(4-clorofenoxi)-2-(trifluorometil)piridin-3-il]-1-ciclopropil-2-(1H-1,2,4-triazol-1-il)etanol. Reivindicación 11: Un método para controlar microorganismos nocivos, preferentemente hongos fitopatogénicos nocivos, en la protección de cultivos y en la protección de materiales, caracterizado porque una combinación de compuestos activos de acuerdo con al menos una de las reivindicaciones 1 a 9 o una composición de acuerdo con la reivindicación 10 se aplica a los microorganismos nocivos y/o a su hábitat. Reivindicación 12: El uso de una combinación de compuestos activos de acuerdo con al menos una de las reivindicaciones 1 a 9 o una composición de acuerdo con la reivindicación 10 para el control de microorganismos nocivos, preferentemente de hongos fitopatogénicos nocivos, en la protección de cultivos y en la protección de materiales.
ARP180100324A 2017-02-10 2018-02-09 Combinaciones de compuestos activos AR110974A1 (es)

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US (1) US20200008426A1 (es)
EP (1) EP3579695A1 (es)
JP (1) JP2020507579A (es)
KR (1) KR20190115449A (es)
CN (1) CN110300522A (es)
AR (1) AR110974A1 (es)
AU (1) AU2018217749A1 (es)
BR (1) BR112019016517A2 (es)
CA (1) CA3052898A1 (es)
CL (1) CL2019002267A1 (es)
CO (1) CO2019008682A2 (es)
CR (1) CR20190365A (es)
EA (1) EA201991853A1 (es)
EC (1) ECSP19057456A (es)
MX (1) MX2019009568A (es)
PH (1) PH12019501835A1 (es)
UY (1) UY37605A (es)
WO (1) WO2018145921A1 (es)

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