AR103194A1 - Formas sólidas de un compuesto antiviral - Google Patents
Formas sólidas de un compuesto antiviralInfo
- Publication number
- AR103194A1 AR103194A1 ARP150101835A ARP150101835A AR103194A1 AR 103194 A1 AR103194 A1 AR 103194A1 AR P150101835 A ARP150101835 A AR P150101835A AR P150101835 A ARP150101835 A AR P150101835A AR 103194 A1 AR103194 A1 AR 103194A1
- Authority
- AR
- Argentina
- Prior art keywords
- methyl
- imidazol
- solid forms
- crystalline
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000007787 solid Substances 0.000 title abstract 3
- 230000000840 anti-viral effect Effects 0.000 title 1
- 125000004485 2-pyrrolidinyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])C1([H])* 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 2
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- -1 naphtho [1,2-d] imidazole- 2-yl Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 1
- 229910002483 Cu Ka Inorganic materials 0.000 abstract 1
- 208000005176 Hepatitis C Diseases 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462010919P | 2014-06-11 | 2014-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR103194A1 true AR103194A1 (es) | 2017-04-26 |
Family
ID=53443009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP150101835A AR103194A1 (es) | 2014-06-11 | 2015-06-10 | Formas sólidas de un compuesto antiviral |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US9630972B2 (https=) |
| EP (3) | EP3822275A1 (https=) |
| JP (3) | JP2017517532A (https=) |
| KR (3) | KR20190007533A (https=) |
| CN (1) | CN106661042A (https=) |
| AR (1) | AR103194A1 (https=) |
| AU (2) | AU2015274961A1 (https=) |
| BR (1) | BR112016028843A2 (https=) |
| CA (1) | CA2951188C (https=) |
| EA (1) | EA201692220A1 (https=) |
| ES (1) | ES2785409T3 (https=) |
| IL (1) | IL249041A0 (https=) |
| MX (1) | MX2016016299A (https=) |
| PL (1) | PL3154983T3 (https=) |
| PT (1) | PT3154983T (https=) |
| SG (1) | SG11201609810YA (https=) |
| SI (1) | SI3154983T1 (https=) |
| TW (1) | TWI721947B (https=) |
| WO (1) | WO2015191431A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2345657A1 (en) | 2003-05-30 | 2011-07-20 | Pharmasset, Inc. | Modified fluorinated nucleoside analogues |
| SI2640719T1 (sl) | 2010-11-17 | 2017-07-31 | Gilead Pharmasset Llc | Antivirusne spojine |
| JP6082749B2 (ja) | 2011-11-16 | 2017-02-15 | ギリアド ファーマセット エルエルシー | 抗ウイルス化合物としての縮合イミダゾリルイミダゾール |
| EA201690473A1 (ru) | 2013-08-27 | 2017-03-31 | ГАЙЛИД ФАРМАССЕТ ЭлЭлСи | Комбинированный состав двух противовирусных соединений |
| TW202014413A (zh) | 2014-06-11 | 2020-04-16 | 美商基利法瑪席特有限責任公司 | 製備抗病毒化合物之方法 |
| TWI721947B (zh) | 2014-06-11 | 2021-03-21 | 美商基利法瑪席特有限責任公司 | 抗病毒化合物的固態形式 |
| JOP20170127A1 (ar) | 2016-06-02 | 2017-12-02 | Gilead Pharmasset Llc | صيغة مشتركة مكونة من ثلاث مركبات مضادة للفيروسات |
| CN108368123B (zh) * | 2016-07-08 | 2021-02-19 | 深圳市塔吉瑞生物医药有限公司 | 一种取代的咪唑基化合物及其药物组合物 |
| CN106432253B (zh) * | 2016-09-21 | 2019-06-14 | 上海众强药业有限公司 | 一种维帕他韦新晶型及其制备方法 |
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| JPWO2004089933A1 (ja) * | 2003-04-02 | 2006-07-06 | アステラス製薬株式会社 | フルオロベンズアミド誘導体の新規結晶 |
| KR101164070B1 (ko) | 2003-05-09 | 2012-07-12 | 베링거 인겔하임 인터내셔날 게엠베하 | Ｃ형 간염 바이러스 ｎｓ5ｂ 폴리머라제 억제제 결합 포켓 |
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| TWI721947B (zh) * | 2014-06-11 | 2021-03-21 | 美商基利法瑪席特有限責任公司 | 抗病毒化合物的固態形式 |
| TW202014413A (zh) | 2014-06-11 | 2020-04-16 | 美商基利法瑪席特有限責任公司 | 製備抗病毒化合物之方法 |
| JP2016051146A (ja) | 2014-09-02 | 2016-04-11 | ウシオ電機株式会社 | 光検出装置 |
| EP3588013A1 (de) | 2018-06-26 | 2020-01-01 | XelectriX Power GmbH | Verfahren zur abgabe von elektrischer energie |
-
2015
- 2015-05-28 TW TW104117182A patent/TWI721947B/zh active
- 2015-06-08 EP EP20213940.8A patent/EP3822275A1/en not_active Withdrawn
- 2015-06-08 KR KR1020197001272A patent/KR20190007533A/ko not_active Ceased
- 2015-06-08 EA EA201692220A patent/EA201692220A1/ru unknown
- 2015-06-08 SG SG11201609810YA patent/SG11201609810YA/en unknown
- 2015-06-08 KR KR1020177000696A patent/KR20170015506A/ko not_active Ceased
- 2015-06-08 PT PT157306218T patent/PT3154983T/pt unknown
- 2015-06-08 US US14/733,101 patent/US9630972B2/en active Active
- 2015-06-08 WO PCT/US2015/034649 patent/WO2015191431A1/en not_active Ceased
- 2015-06-08 CN CN201580031460.3A patent/CN106661042A/zh active Pending
- 2015-06-08 KR KR1020207036803A patent/KR20200145852A/ko not_active Ceased
- 2015-06-08 AU AU2015274961A patent/AU2015274961A1/en not_active Abandoned
- 2015-06-08 MX MX2016016299A patent/MX2016016299A/es unknown
- 2015-06-08 PL PL15730621T patent/PL3154983T3/pl unknown
- 2015-06-08 CA CA2951188A patent/CA2951188C/en active Active
- 2015-06-08 EP EP15730621.8A patent/EP3154983B1/en active Active
- 2015-06-08 BR BR112016028843A patent/BR112016028843A2/pt not_active IP Right Cessation
- 2015-06-08 ES ES15730621T patent/ES2785409T3/es active Active
- 2015-06-08 EP EP20155444.1A patent/EP3666775A1/en not_active Withdrawn
- 2015-06-08 SI SI201531097T patent/SI3154983T1/sl unknown
- 2015-06-08 JP JP2016572253A patent/JP2017517532A/ja not_active Withdrawn
- 2015-06-10 AR ARP150101835A patent/AR103194A1/es unknown
-
2016
- 2016-11-17 IL IL249041A patent/IL249041A0/en unknown
-
2017
- 2017-03-15 US US15/459,785 patent/US9884873B2/en active Active
- 2017-12-18 US US15/845,837 patent/US10604530B2/en active Active
-
2018
- 2018-03-19 AU AU2018201948A patent/AU2018201948B2/en active Active
-
2019
- 2019-02-18 JP JP2019026534A patent/JP2019070057A/ja not_active Ceased
- 2019-07-19 JP JP2019133593A patent/JP2019172711A/ja active Pending
-
2020
- 2020-02-21 US US16/797,793 patent/US11203599B2/en active Active
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