AR103082A1 - Purificación de polisacárido capsular de estreptococos - Google Patents
Purificación de polisacárido capsular de estreptococosInfo
- Publication number
- AR103082A1 AR103082A1 ARP150104156A ARP150104156A AR103082A1 AR 103082 A1 AR103082 A1 AR 103082A1 AR P150104156 A ARP150104156 A AR P150104156A AR P150104156 A ARP150104156 A AR P150104156A AR 103082 A1 AR103082 A1 AR 103082A1
- Authority
- AR
- Argentina
- Prior art keywords
- purification
- capsular
- polisacárid
- streptococ
- capsular polysaccharide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
Abstract
Un procedimiento de purificación para el polisacárido capsular de GBS de tipo II en la que el polisacárido capsular se filtra utilizando una membrana con un punto de corte de menos de 30 kDa. Este procedimiento proporciona un rendimiento más alto que los protocolos anteriores.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14199441.8A EP3034516A1 (en) | 2014-12-19 | 2014-12-19 | Purification of streptococcal capsular polysaccharide |
Publications (1)
Publication Number | Publication Date |
---|---|
AR103082A1 true AR103082A1 (es) | 2017-04-12 |
Family
ID=52231940
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP150104156A AR103082A1 (es) | 2014-12-19 | 2015-12-17 | Purificación de polisacárido capsular de estreptococos |
Country Status (6)
Country | Link |
---|---|
US (1) | US10172928B2 (es) |
EP (3) | EP3034516A1 (es) |
AR (1) | AR103082A1 (es) |
BE (1) | BE1023297B1 (es) |
ES (1) | ES2942133T3 (es) |
WO (1) | WO2016097147A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113234770A (zh) * | 2021-06-15 | 2021-08-10 | 广州知易生物科技有限公司 | 脆弱拟杆菌荚膜多糖a的制备方法 |
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BE889979A (fr) | 1981-08-14 | 1982-02-15 | Smith Kline Rit | Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation |
US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
US4459286A (en) | 1983-01-31 | 1984-07-10 | Merck & Co., Inc. | Coupled H. influenzae type B vaccine |
US4663160A (en) | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
US4761283A (en) | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
US4882317A (en) | 1984-05-10 | 1989-11-21 | Merck & Co., Inc. | Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency |
US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
US4808700A (en) | 1984-07-09 | 1989-02-28 | Praxis Biologics, Inc. | Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers |
IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
NL8802046A (nl) | 1988-08-18 | 1990-03-16 | Gen Electric | Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen. |
DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
EP0378881B1 (en) | 1989-01-17 | 1993-06-09 | ENIRICERCHE S.p.A. | Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines |
EP0482068A1 (en) | 1989-07-14 | 1992-04-29 | American Cyanamid Company | Cytokine and hormone carriers for conjugate vaccines |
IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
DE69113564T2 (de) | 1990-08-13 | 1996-05-30 | American Cyanamid Co | Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff. |
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IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
ATE254475T1 (de) | 1993-09-22 | 2003-12-15 | Jackson H M Found Military Med | Verfahren zur aktivierung von löslichem kohlenhydraten durch verwendung von neuen cyanylierungsreagenzien, zur herstellung von immunogenischen konstrukten |
DE4432628B4 (de) * | 1994-09-14 | 2008-01-10 | Sartorius Biotech Gmbh | Dead-End-Filtrationseinheit zur Abtrennung von Stoffen mit Membranadsorbern |
CA2221511C (en) | 1995-06-07 | 2013-01-08 | Smithkline Beecham Biologicals S.A. | Vaccine comprising a polysaccharide antigen-carrier protein conjugate and free carrier protein |
US6891037B1 (en) | 1997-01-24 | 2005-05-10 | Schweiz. Serum- & Impfinstitut Bern | Method for the isolation of polysaccharides |
US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
EP2226336B1 (en) * | 1997-12-23 | 2016-10-19 | Pfizer Ireland Pharmaceuticals | Bacterial capsular polysaccharide for use as vaccines or for linking to proteins in conjugate vaccines |
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US20070053924A1 (en) | 2002-08-26 | 2007-03-08 | Herve Tettelin | Conserved and specific streptococcal genomes |
GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
GB0502096D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Purification of streptococcal capsular polysaccharide |
JP5286089B2 (ja) * | 2006-01-13 | 2013-09-11 | バクスター・インターナショナル・インコーポレイテッド | ポリサッカライドを精製する方法 |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
JP2011515170A (ja) * | 2008-03-28 | 2011-05-19 | リサーチ ファンデーション フォー メディカル デバイシズ | 溶媒/界面活性剤処理による生体液のウイルス不活化方法 |
EP2356135B1 (en) | 2008-11-05 | 2017-10-25 | Wyeth LLC | Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (bhs) disease |
GB201101665D0 (en) | 2011-01-31 | 2011-03-16 | Novartis Ag | Immunogenic compositions |
EP3140414B1 (en) | 2014-05-07 | 2022-10-26 | GlaxoSmithKline Biologicals S.A. | Purification of secreted polysaccharides from s. agalactiae |
-
2014
- 2014-12-19 EP EP14199441.8A patent/EP3034516A1/en not_active Ceased
-
2015
- 2015-12-17 US US15/536,132 patent/US10172928B2/en active Active
- 2015-12-17 AR ARP150104156A patent/AR103082A1/es unknown
- 2015-12-17 BE BE2015/5825A patent/BE1023297B1/fr active
- 2015-12-17 EP EP23153341.5A patent/EP4201965A1/en active Pending
- 2015-12-17 EP EP15813399.1A patent/EP3233927B1/en active Active
- 2015-12-17 WO PCT/EP2015/080228 patent/WO2016097147A1/en active Application Filing
- 2015-12-17 ES ES15813399T patent/ES2942133T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
US20170348408A1 (en) | 2017-12-07 |
ES2942133T3 (es) | 2023-05-30 |
BE1023297A1 (fr) | 2017-01-26 |
BE1023297B1 (fr) | 2017-01-26 |
US10172928B2 (en) | 2019-01-08 |
EP3034516A1 (en) | 2016-06-22 |
EP4201965A1 (en) | 2023-06-28 |
WO2016097147A1 (en) | 2016-06-23 |
EP3233927B1 (en) | 2023-03-08 |
EP3233927A1 (en) | 2017-10-25 |
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