AR089122A1 - Formulaciones orales para tratar la sobrecarga de metales - Google Patents
Formulaciones orales para tratar la sobrecarga de metalesInfo
- Publication number
- AR089122A1 AR089122A1 ARP120104611A ARP120104611A AR089122A1 AR 089122 A1 AR089122 A1 AR 089122A1 AR P120104611 A ARP120104611 A AR P120104611A AR P120104611 A ARP120104611 A AR P120104611A AR 089122 A1 AR089122 A1 AR 089122A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydroxy
- integer
- hydrogen
- independently selected
- alkoxy
- Prior art date
Links
- 239000002184 metal Substances 0.000 title abstract 3
- 229910052751 metal Inorganic materials 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical group [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 239000007909 solid dosage form Substances 0.000 abstract 2
- 206010065973 Iron Overload Diseases 0.000 abstract 1
- 239000004721 Polyphenylene oxide Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000007922 dissolution test Methods 0.000 abstract 1
- 229920000570 polyether Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161568890P | 2011-12-09 | 2011-12-09 | |
| US201161568914P | 2011-12-09 | 2011-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR089122A1 true AR089122A1 (es) | 2014-07-30 |
Family
ID=48574916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120104611A AR089122A1 (es) | 2011-12-09 | 2012-12-07 | Formulaciones orales para tratar la sobrecarga de metales |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8993606B2 (OSRAM) |
| EP (1) | EP2787994A4 (OSRAM) |
| JP (1) | JP2015500294A (OSRAM) |
| AR (1) | AR089122A1 (OSRAM) |
| AU (1) | AU2012347595A1 (OSRAM) |
| BR (1) | BR112014013985A2 (OSRAM) |
| CA (1) | CA2857990A1 (OSRAM) |
| TW (1) | TW201338777A (OSRAM) |
| WO (1) | WO2013086312A1 (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6539046B2 (ja) | 2011-12-16 | 2019-07-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション， インク． | ４’−デスフェリチオシン類似体の使用 |
| CA2905026A1 (en) | 2013-03-15 | 2014-09-18 | Ferrokin Biosciences, Inc. | Polymorph forms of desazadesferrithiocin analogs |
| EP3071201A4 (en) * | 2013-11-22 | 2017-04-26 | University of Florida Research Foundation, Inc. | Desferrithiocin analogs and uses thereof |
| CN107708693A (zh) | 2015-04-27 | 2018-02-16 | 佛罗里达大学研究基金会 | 代谢程序化的金属螯合剂及其用途 |
| WO2018104130A1 (en) | 2016-12-07 | 2018-06-14 | Lumileds Holding B.V. | Flash light emitter with remote communication function |
| CN114302882A (zh) * | 2019-07-19 | 2022-04-08 | 威佛（国际）股份公司 | 用于治疗输血依赖型β-地中海贫血（tdt）的膜铁转运蛋白抑制剂 |
| JP2024504349A (ja) | 2021-01-20 | 2024-01-31 | ビフォー （インターナショナル） エージー | 骨髄異形成症候群（ｍｄｓ）の処置において使用するためのフェロポーチン阻害剤 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1866296T3 (en) | 2005-04-04 | 2017-02-13 | Univ Florida | DESFERRITHIOCINPOLYETHER-ANALOGS |
| US8067451B2 (en) * | 2006-07-18 | 2011-11-29 | Horizon Pharma Usa, Inc. | Methods and medicaments for administration of ibuprofen |
| BRPI0809077A2 (pt) | 2007-03-15 | 2014-09-09 | Univ Florida Res Foudantion Inc | Análogos de poliéter de desferritiocina |
| WO2010009120A2 (en) * | 2008-07-14 | 2010-01-21 | Ferrokin Biosciences, Inc. | Novel salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents |
| WO2011017054A2 (en) | 2009-07-27 | 2011-02-10 | Ferrokin Biosciences, Inc. | Prodrugs of desazadesferrothiocin polyether analogues as metal chelation agents |
| US20120184586A1 (en) | 2009-08-25 | 2012-07-19 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues and uses thereof |
| AU2011248158A1 (en) | 2010-05-04 | 2012-12-20 | Ferrokin Biosciences, Inc. | Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents |
-
2012
- 2012-12-07 EP EP12856135.4A patent/EP2787994A4/en not_active Withdrawn
- 2012-12-07 US US13/708,087 patent/US8993606B2/en not_active Expired - Fee Related
- 2012-12-07 CA CA2857990A patent/CA2857990A1/en not_active Abandoned
- 2012-12-07 BR BR112014013985A patent/BR112014013985A2/pt not_active IP Right Cessation
- 2012-12-07 AU AU2012347595A patent/AU2012347595A1/en not_active Abandoned
- 2012-12-07 TW TW101146269A patent/TW201338777A/zh unknown
- 2012-12-07 WO PCT/US2012/068432 patent/WO2013086312A1/en not_active Ceased
- 2012-12-07 AR ARP120104611A patent/AR089122A1/es not_active Application Discontinuation
- 2012-12-07 JP JP2014546115A patent/JP2015500294A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2787994A1 (en) | 2014-10-15 |
| AU2012347595A1 (en) | 2014-06-26 |
| US20130225645A1 (en) | 2013-08-29 |
| WO2013086312A1 (en) | 2013-06-13 |
| BR112014013985A2 (pt) | 2017-06-13 |
| TW201338777A (zh) | 2013-10-01 |
| EP2787994A4 (en) | 2015-08-26 |
| JP2015500294A (ja) | 2015-01-05 |
| US8993606B2 (en) | 2015-03-31 |
| CA2857990A1 (en) | 2013-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |