AR088971A1 - INHIBIDOR DE a₁-PROTEINASA PARA DEMORAR EL COMIENZO O PROGRESION DE EXACERBACIONES PULMONARES - Google Patents
INHIBIDOR DE a₁-PROTEINASA PARA DEMORAR EL COMIENZO O PROGRESION DE EXACERBACIONES PULMONARESInfo
- Publication number
- AR088971A1 AR088971A1 ARP120104411A ARP120104411A AR088971A1 AR 088971 A1 AR088971 A1 AR 088971A1 AR P120104411 A ARP120104411 A AR P120104411A AR P120104411 A ARP120104411 A AR P120104411A AR 088971 A1 AR088971 A1 AR 088971A1
- Authority
- AR
- Argentina
- Prior art keywords
- progression
- beginning
- delay
- proteinase inhibitor
- pulmonary exacerbations
- Prior art date
Links
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title abstract 2
- 230000002685 pulmonary effect Effects 0.000 title abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000005713 exacerbation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0018—Details of inhalators; Constructional features thereof with exhalation check valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161581708P | 2011-12-30 | 2011-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR088971A1 true AR088971A1 (es) | 2014-07-23 |
Family
ID=47470050
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120104411A AR088971A1 (es) | 2011-12-30 | 2012-11-23 | INHIBIDOR DE a₁-PROTEINASA PARA DEMORAR EL COMIENZO O PROGRESION DE EXACERBACIONES PULMONARES |
| ARP190103126A AR116887A2 (es) | 2011-12-30 | 2019-10-29 | Kit para demorar el comienzo o disminuir la progresión de exacerbaciones pulmonares |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP190103126A AR116887A2 (es) | 2011-12-30 | 2019-10-29 | Kit para demorar el comienzo o disminuir la progresión de exacerbaciones pulmonares |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9421248B2 (enExample) |
| EP (1) | EP2758065B1 (enExample) |
| JP (4) | JP2015504051A (enExample) |
| KR (1) | KR20140108516A (enExample) |
| CN (2) | CN107596359A (enExample) |
| AR (2) | AR088971A1 (enExample) |
| AU (1) | AU2012337241B2 (enExample) |
| BR (1) | BR112014007127A2 (enExample) |
| CA (1) | CA2844878C (enExample) |
| CL (1) | CL2014000722A1 (enExample) |
| ES (1) | ES2887358T3 (enExample) |
| IL (1) | IL231109B (enExample) |
| MX (1) | MX351189B (enExample) |
| MY (1) | MY166314A (enExample) |
| RU (1) | RU2635482C2 (enExample) |
| SG (2) | SG10201610913PA (enExample) |
| UY (1) | UY34465A (enExample) |
| WO (1) | WO2013098672A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20160054475A (ko) * | 2013-08-05 | 2016-05-16 | 제라드 뵈르만 | 흡연의 해로운 영향을 감소시키는 신규의 수단 |
| EP3236772A4 (en) * | 2014-12-22 | 2018-10-17 | Alexion Pharmaceuticals, Inc. | Methods of purifying recombinant proteins |
| RS65152B1 (sr) * | 2015-02-05 | 2024-02-29 | Canem Holdings Llc | Preparati za lečenje granulomatoze sa poliangiitisom |
| WO2018154568A1 (en) | 2017-02-21 | 2018-08-30 | Kamada Ltd. | Methods and uses of alpha 1-antitrypsin for early intervention in pulmonary diseases |
| US10663434B2 (en) * | 2017-03-31 | 2020-05-26 | Sonix, Inc. | Wafer chuck |
| WO2020014326A1 (en) * | 2018-07-10 | 2020-01-16 | Ciancone Christopher V | Breath measurement device |
| WO2021028927A1 (en) * | 2019-08-15 | 2021-02-18 | Kamada Ltd | Combination of alpha-1-antitrypsin and steroids and uses therefor |
| TW202122086A (zh) * | 2019-08-23 | 2021-06-16 | 韓商Ｐｈ製藥公司 | 嗜中性白血球彈性蛋白酶抑制劑在肺部疾病中之使用 |
| US20230302104A1 (en) * | 2020-05-01 | 2023-09-28 | Atlas Biotechnology S.A. | Treatment and/or prevention of a disease or a syndrome related to a virus infection |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE395611B (sv) | 1975-12-12 | 1977-08-22 | Draco Ab | Aerosolinhalationsanordning avsedd for inhalering genom ett inhaleringsmunstycke av farmakologiskt aktiva substanser |
| SE411705B (sv) | 1976-11-09 | 1980-02-04 | Draco Ab | Anordning for generering av en avskermad, vesentligen drivmedelsfri aerosol |
| DE3274065D1 (de) | 1981-07-08 | 1986-12-11 | Draco Ab | Powder inhalator |
| US5218091A (en) | 1982-08-13 | 1993-06-08 | Zymogenetics, Inc. | Glycolytic promoters for regulated protein expression: protease inhibitor |
| US4667688A (en) | 1983-11-28 | 1987-05-26 | Francisco Roig | Mini pack of cigarettes |
| US4711848A (en) | 1984-03-14 | 1987-12-08 | Zymogenetics, Inc. | Site specific mutagenesis in alpha-1-antitrypsin |
| US4931373A (en) | 1984-05-25 | 1990-06-05 | Zymogenetics, Inc. | Stable DNA constructs for expression of α-1 antitrypsin |
| US4732973A (en) | 1984-06-14 | 1988-03-22 | Chiron Corporation | Active site modified protease α-1-antitrypsin inhibitors |
| EP0169114B1 (fr) | 1984-06-19 | 1991-01-16 | Transgene S.A. | Dérivés de l'alpha 1-antitrypsine humaine et procédé pour leur préparation |
| US4697003A (en) | 1985-11-01 | 1987-09-29 | Miles Laboratories, Inc. | Method of preparing alpha-1-proteinase inhibitor |
| US5366894A (en) | 1986-06-30 | 1994-11-22 | Pharmaceutical Proteins Limited | Peptide production |
| US5093316A (en) | 1986-12-24 | 1992-03-03 | John Lezdey | Treatment of inflammation |
| JP2656944B2 (ja) | 1987-04-30 | 1997-09-24 | クーパー ラボラトリーズ | タンパク質性治療剤のエアロゾール化 |
| US5079336A (en) | 1989-06-23 | 1992-01-07 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
| US5134119A (en) | 1990-10-16 | 1992-07-28 | Lezdey John | Treatment of inflammation using 358 substituted alpha-antitrypsin |
| US5915378A (en) | 1993-01-29 | 1999-06-29 | Aradigm Corporation | Creating an aerosolized formulation of insulin |
| US5672581A (en) | 1993-01-29 | 1997-09-30 | Aradigm Corporation | Method of administration of insulin |
| US5497763A (en) | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| US5709202A (en) | 1993-05-21 | 1998-01-20 | Aradigm Corporation | Intrapulmonary delivery of aerosolized formulations |
| ATE416755T1 (de) | 1994-03-07 | 2008-12-15 | Nektar Therapeutics | Verfahren und zusammensetzung für die pulmonale darreichung von insulin |
| MX9605717A (es) | 1994-05-18 | 1998-05-31 | Inhale Therapeutic Syst | Metodos y composiciones para la formulacion de polvo seco de interferones. |
| US5610285A (en) | 1994-08-24 | 1997-03-11 | Bayer Corporation | Purification of α-1 proteinase inhibitor using novel chromatographic separation conditions |
| US5780014A (en) | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| AU6884396A (en) | 1995-09-07 | 1997-03-27 | Ppl Therapeutics (Scotland) Ltd | Purification of alpha-1 proteinase inhibitor |
| US5780440A (en) | 1996-06-17 | 1998-07-14 | Protease Sciences Inc. | Treatment of pulmonary disease with protease inhibitors |
| AT407114B (de) | 1997-06-10 | 2000-12-27 | Immuno Ag | Alpha 1-antitrypsin-präparation sowie verfahren zu deren herstellung |
| OA11529A (en) | 1998-03-16 | 2004-05-07 | Inhale Therapeutic Syst | Aerosolized active agent delivery. |
| US6093804A (en) | 1998-09-24 | 2000-07-25 | American National Red Cross | Method for purification of alpha-1 proteinase inhibitor |
| US6397838B1 (en) | 1998-12-23 | 2002-06-04 | Battelle Pulmonary Therapeutics, Inc. | Pulmonary aerosol delivery device and method |
| DE19953317C1 (de) | 1999-11-05 | 2001-02-01 | Pari Gmbh | Inhalationsvernebler |
| US6462180B1 (en) | 1999-11-24 | 2002-10-08 | Bayer Corporation | Method of preparing α-1 proteinase inhibitor |
| EP1366175B1 (en) | 2000-12-18 | 2008-01-23 | Arriva Pharmaceuticals, Inc. | Multifunctional protease inhibitors and their use in treatment of disease |
| PT1664123E (pt) | 2003-09-22 | 2008-07-16 | Kamada Ltd | Preparação em larga escala de um inibidor da alfa-1 proteinase e sua utilização |
| ATE530165T1 (de) * | 2003-11-14 | 2011-11-15 | Baxter Int | Alpha1-antitrypsin-zusammensetzungen und behandlungsverfahren unter verwendung dieser zusammensetzungen |
| EP1737499A4 (en) | 2004-03-09 | 2009-07-22 | Arriva Pharmaceuticals Inc | TREATMENT OF CHRONIC OBSTRUCTIVE LUNG DISEASE BY INHALATION OF LOW DOSES OF A PROTEASE HEMMER |
| EP1981572B1 (en) * | 2006-02-09 | 2012-11-21 | Kamada Ltd. | Pulmonary delivery of alpha-i proteinase inhibitor |
| US20080078382A1 (en) | 2006-09-20 | 2008-04-03 | Lemahieu Edward | Methods and Systems of Delivering Medication Via Inhalation |
| EP1927373B1 (en) | 2006-11-30 | 2012-08-22 | PARI Pharma GmbH | Inhalation nebulizer |
| EP2321336A1 (en) | 2008-07-18 | 2011-05-18 | Talecris Biotherapeutics, Inc. | Method of preparing alpha-1 proteinase inhibitor |
| AU2010315325B2 (en) | 2009-11-03 | 2014-11-27 | Grifols Therapeutics Inc. | Composition, method, and kit for alpha-1 proteinase inhibitor |
-
2012
- 2012-11-22 KR KR1020147006804A patent/KR20140108516A/ko not_active Ceased
- 2012-11-22 EP EP12808897.8A patent/EP2758065B1/en active Active
- 2012-11-22 US US14/369,662 patent/US9421248B2/en active Active
- 2012-11-22 ES ES12808897T patent/ES2887358T3/es active Active
- 2012-11-22 CN CN201710789166.XA patent/CN107596359A/zh active Pending
- 2012-11-22 CN CN201280048668.2A patent/CN103889436A/zh active Pending
- 2012-11-22 AU AU2012337241A patent/AU2012337241B2/en active Active
- 2012-11-22 SG SG10201610913PA patent/SG10201610913PA/en unknown
- 2012-11-22 SG SG2014012066A patent/SG2014012066A/en unknown
- 2012-11-22 MY MYPI2014700341A patent/MY166314A/en unknown
- 2012-11-22 MX MX2014001764A patent/MX351189B/es active IP Right Grant
- 2012-11-22 CA CA2844878A patent/CA2844878C/en active Active
- 2012-11-22 RU RU2014106758A patent/RU2635482C2/ru active
- 2012-11-22 WO PCT/IB2012/056616 patent/WO2013098672A2/en not_active Ceased
- 2012-11-22 BR BR112014007127A patent/BR112014007127A2/pt not_active IP Right Cessation
- 2012-11-22 JP JP2014549567A patent/JP2015504051A/ja active Pending
- 2012-11-23 AR ARP120104411A patent/AR088971A1/es not_active Application Discontinuation
- 2012-11-23 UY UY0001034465A patent/UY34465A/es not_active Application Discontinuation
-
2014
- 2014-02-24 IL IL231109A patent/IL231109B/en active IP Right Grant
- 2014-03-24 CL CL2014000722A patent/CL2014000722A1/es unknown
-
2016
- 2016-10-05 JP JP2016197058A patent/JP2017039745A/ja active Pending
-
2018
- 2018-01-25 JP JP2018010440A patent/JP2018104439A/ja active Pending
-
2019
- 2019-04-02 JP JP2019070581A patent/JP2019135243A/ja active Pending
- 2019-10-29 AR ARP190103126A patent/AR116887A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015504051A (ja) | 2015-02-05 |
| JP2017039745A (ja) | 2017-02-23 |
| SG10201610913PA (en) | 2017-02-27 |
| JP2018104439A (ja) | 2018-07-05 |
| ES2887358T3 (es) | 2021-12-22 |
| IL231109B (en) | 2018-02-28 |
| AR116887A2 (es) | 2021-06-23 |
| EP2758065A2 (en) | 2014-07-30 |
| CL2014000722A1 (es) | 2014-10-10 |
| CN103889436A (zh) | 2014-06-25 |
| US9421248B2 (en) | 2016-08-23 |
| CN107596359A (zh) | 2018-01-19 |
| JP2019135243A (ja) | 2019-08-15 |
| WO2013098672A2 (en) | 2013-07-04 |
| CA2844878C (en) | 2017-11-28 |
| CA2844878A1 (en) | 2013-07-04 |
| BR112014007127A2 (pt) | 2017-04-04 |
| IL231109A0 (en) | 2014-04-30 |
| RU2635482C2 (ru) | 2017-11-13 |
| US20150011460A1 (en) | 2015-01-08 |
| NZ621596A (en) | 2016-08-26 |
| MX351189B (es) | 2017-10-04 |
| MY166314A (en) | 2018-06-25 |
| KR20140108516A (ko) | 2014-09-11 |
| RU2014106758A (ru) | 2015-08-27 |
| WO2013098672A3 (en) | 2013-10-24 |
| MX2014001764A (es) | 2014-04-30 |
| AU2012337241B2 (en) | 2016-10-13 |
| UY34465A (es) | 2013-07-31 |
| EP2758065B1 (en) | 2021-06-23 |
| AU2012337241A1 (en) | 2013-07-18 |
| SG2014012066A (en) | 2014-09-26 |
| HK1198918A1 (en) | 2015-06-19 |
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