AR082674A1 - Tratamiento de diabetes con celulas precursoras pancreaticas endocrinas - Google Patents
Tratamiento de diabetes con celulas precursoras pancreaticas endocrinasInfo
- Publication number
- AR082674A1 AR082674A1 ARP110102941A ARP110102941A AR082674A1 AR 082674 A1 AR082674 A1 AR 082674A1 AR P110102941 A ARP110102941 A AR P110102941A AR P110102941 A ARP110102941 A AR P110102941A AR 082674 A1 AR082674 A1 AR 082674A1
- Authority
- AR
- Argentina
- Prior art keywords
- precursor cells
- diabetes
- treatment
- pancreatic precursor
- endocrine pancreatic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
Abstract
Método para reducir los niveles de glucosa en sangre en un animal mediante el trasplante de una población de células precursoras endócrinas pancreáticas en un animal.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37310910P | 2010-08-12 | 2010-08-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR082674A1 true AR082674A1 (es) | 2012-12-26 |
Family
ID=45564982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP110102941A AR082674A1 (es) | 2010-08-12 | 2011-08-12 | Tratamiento de diabetes con celulas precursoras pancreaticas endocrinas |
Country Status (15)
Country | Link |
---|---|
US (1) | US20120039955A1 (es) |
EP (2) | EP3981415A1 (es) |
JP (5) | JP2013533319A (es) |
KR (3) | KR20180032674A (es) |
CN (1) | CN103052393B (es) |
AR (1) | AR082674A1 (es) |
AU (1) | AU2011289379A1 (es) |
BR (1) | BR112013003160A2 (es) |
CA (1) | CA2807158A1 (es) |
DK (1) | DK2603226T3 (es) |
MX (1) | MX2013001673A (es) |
RU (2) | RU2013110524A (es) |
SG (2) | SG10201506264QA (es) |
WO (1) | WO2012021698A2 (es) |
ZA (1) | ZA201301836B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2902650T3 (es) | 2011-06-21 | 2022-03-29 | Novo Nordisk As | Inducción eficiente de endodermo definitivo a partir de células madre pluripotentes |
RU2016100219A (ru) * | 2013-06-11 | 2017-07-17 | Президент Энд Феллоус Оф Гарвард Колледж | КЛЕТКИ SC-β И КОМПОЗИЦИИ, И СПОСОБЫ ДЛЯ ИХ СОЗДАНИЯ |
US20170175081A1 (en) * | 2014-05-14 | 2017-06-22 | The University Court Of The University Of Aberdeen | Methods of Obtaining Islet Cells |
EP3143128A1 (en) | 2014-05-14 | 2017-03-22 | The University Court of The University of Aberdeen | Methods of obtaining pancreatic endocrine cells |
EP3234110B1 (en) | 2014-12-18 | 2024-02-28 | President and Fellows of Harvard College | METHODS FOR GENERATING STEM CELL-DERIVED ß CELLS AND USES THEREOF |
US10253298B2 (en) | 2014-12-18 | 2019-04-09 | President And Fellows Of Harvard College | Methods for generating stem cell-derived beta cells and methods of use thereof |
US10443042B2 (en) | 2014-12-18 | 2019-10-15 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof |
EP3268016B1 (en) * | 2015-03-11 | 2021-04-28 | CCS Ventures Limited | Pancreatic endocrine progenitor cell therapies for the treatment of obesity and type 2 diabetes (t2d) |
JP7088564B2 (ja) * | 2016-11-10 | 2022-06-21 | ヴィアサイト,インコーポレイテッド | 細胞送達装置におけるpdx1膵臓内胚葉細胞及びその方法 |
US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
IL305391A (en) | 2017-11-15 | 2023-10-01 | Vertex Pharma | Preparations for the production of islet cells and methods of use |
AU2019320072A1 (en) | 2018-08-10 | 2021-02-25 | Vertex Pharmaceuticals Incorporated | Stem cell derived islet differentiation |
CA3139591C (en) | 2019-05-31 | 2024-01-16 | Timothy M. BRUHN | A biocompatible membrane composite |
CN114173837A (zh) | 2019-05-31 | 2022-03-11 | W.L.戈尔及同仁股份有限公司 | 生物相容性膜复合材料 |
EP3975926A1 (en) | 2019-05-31 | 2022-04-06 | W.L. Gore & Associates, Inc. | A biocompatible membrane composite |
CN114401752B (zh) | 2019-05-31 | 2023-04-04 | W.L.戈尔及同仁股份有限公司 | 具有受控氧扩散距离的细胞封装装置 |
KR102247950B1 (ko) * | 2019-10-16 | 2021-05-04 | 가톨릭대학교 산학협력단 | 이식 후 당뇨병의 발병 위험도 예측 방법 |
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-
2011
- 2011-08-11 JP JP2013524228A patent/JP2013533319A/ja not_active Withdrawn
- 2011-08-11 WO PCT/US2011/047410 patent/WO2012021698A2/en active Application Filing
- 2011-08-11 EP EP21167043.5A patent/EP3981415A1/en active Pending
- 2011-08-11 RU RU2013110524/15A patent/RU2013110524A/ru unknown
- 2011-08-11 DK DK11817033.1T patent/DK2603226T3/da active
- 2011-08-11 MX MX2013001673A patent/MX2013001673A/es not_active Application Discontinuation
- 2011-08-11 AU AU2011289379A patent/AU2011289379A1/en not_active Abandoned
- 2011-08-11 SG SG10201506264QA patent/SG10201506264QA/en unknown
- 2011-08-11 SG SG2013005921A patent/SG187603A1/en unknown
- 2011-08-11 BR BR112013003160A patent/BR112013003160A2/pt not_active Application Discontinuation
- 2011-08-11 US US13/207,905 patent/US20120039955A1/en not_active Abandoned
- 2011-08-11 KR KR1020187007871A patent/KR20180032674A/ko active Application Filing
- 2011-08-11 EP EP11817033.1A patent/EP2603226B1/en active Active
- 2011-08-11 RU RU2016133754A patent/RU2682719C2/ru active
- 2011-08-11 CA CA2807158A patent/CA2807158A1/en active Pending
- 2011-08-11 KR KR1020137005824A patent/KR20130100122A/ko active Application Filing
- 2011-08-11 KR KR1020197007026A patent/KR20190027969A/ko not_active Application Discontinuation
- 2011-08-11 CN CN201180038871.7A patent/CN103052393B/zh active Active
- 2011-08-12 AR ARP110102941A patent/AR082674A1/es unknown
-
2013
- 2013-03-11 ZA ZA2013/01836A patent/ZA201301836B/en unknown
-
2016
- 2016-08-26 JP JP2016165581A patent/JP2017031163A/ja active Pending
-
2019
- 2019-03-06 JP JP2019040598A patent/JP2019131564A/ja active Pending
-
2020
- 2020-08-06 JP JP2020133922A patent/JP7012128B2/ja active Active
-
2022
- 2022-01-14 JP JP2022004689A patent/JP2022058629A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CN103052393A (zh) | 2013-04-17 |
CA2807158A1 (en) | 2012-02-16 |
RU2682719C2 (ru) | 2019-03-21 |
JP2013533319A (ja) | 2013-08-22 |
JP2020196728A (ja) | 2020-12-10 |
SG10201506264QA (en) | 2015-09-29 |
SG187603A1 (en) | 2013-03-28 |
RU2016133754A3 (es) | 2018-12-10 |
WO2012021698A2 (en) | 2012-02-16 |
JP2019131564A (ja) | 2019-08-08 |
KR20180032674A (ko) | 2018-03-30 |
EP2603226A4 (en) | 2014-01-15 |
RU2013110524A (ru) | 2014-09-20 |
JP7012128B2 (ja) | 2022-01-27 |
WO2012021698A3 (en) | 2012-05-10 |
MX2013001673A (es) | 2013-03-25 |
ZA201301836B (en) | 2018-12-19 |
RU2016133754A (ru) | 2018-12-10 |
CN103052393B (zh) | 2017-11-14 |
US20120039955A1 (en) | 2012-02-16 |
KR20130100122A (ko) | 2013-09-09 |
AU2011289379A1 (en) | 2013-02-07 |
EP2603226B1 (en) | 2021-04-07 |
DK2603226T3 (da) | 2021-06-07 |
JP2022058629A (ja) | 2022-04-12 |
EP2603226A2 (en) | 2013-06-19 |
BR112013003160A2 (pt) | 2016-06-28 |
JP2017031163A (ja) | 2017-02-09 |
EP3981415A1 (en) | 2022-04-13 |
KR20190027969A (ko) | 2019-03-15 |
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