AR078281A1 - Formulacion estable de hialuronano / esteroide - Google Patents

Formulacion estable de hialuronano / esteroide

Info

Publication number
AR078281A1
AR078281A1 ARP100103295A ARP100103295A AR078281A1 AR 078281 A1 AR078281 A1 AR 078281A1 AR P100103295 A ARP100103295 A AR P100103295A AR P100103295 A ARP100103295 A AR P100103295A AR 078281 A1 AR078281 A1 AR 078281A1
Authority
AR
Argentina
Prior art keywords
composition
stable
harc
pharmaceutical composition
hialuronan
Prior art date
Application number
ARP100103295A
Other languages
English (en)
Spanish (es)
Inventor
Grace Chang
Li-Ping Yu
Eugene Skrabut
Elizabeth Voschin
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of AR078281A1 publication Critical patent/AR078281A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ARP100103295A 2009-09-10 2010-09-08 Formulacion estable de hialuronano / esteroide AR078281A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/556,869 US8273725B2 (en) 2009-09-10 2009-09-10 Stable hyaluronan/steroid formulation

Publications (1)

Publication Number Publication Date
AR078281A1 true AR078281A1 (es) 2011-10-26

Family

ID=43648224

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100103295A AR078281A1 (es) 2009-09-10 2010-09-08 Formulacion estable de hialuronano / esteroide

Country Status (8)

Country Link
US (2) US8273725B2 (https=)
EP (2) EP2475251B1 (https=)
JP (2) JP6121717B2 (https=)
CN (1) CN102573468B (https=)
AR (1) AR078281A1 (https=)
BR (1) BR112012005423B1 (https=)
MX (1) MX2012002830A (https=)
WO (1) WO2011031402A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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CA2633978A1 (en) 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Bioabsorbable implant of hyaluronic acid derivative for treatment of osteochondral and chondral defects
CN102573941B (zh) 2009-07-30 2014-10-29 卡比兰生物外科公司 改性透明质酸聚合物组合物和相关的方法
ES2537411T3 (es) 2011-04-20 2015-06-08 Carbylan Therapeutics, Inc. Composiciones formadoras de gel in situ
TWI424007B (zh) 2011-12-22 2014-01-21 Ind Tech Res Inst 使膠體交聯的方法與藉由此方法形成之經交聯的膠體
WO2014110454A1 (en) * 2013-01-11 2014-07-17 Carbylan Biosurgery, Inc. Stabilized compositions comprising hyaluronic acid
IT201600075246A1 (it) * 2016-07-19 2018-01-19 Jointherapeutics S R L Composizioni comprendenti una matrice polisaccaridica per il rilascio controllato di principi attivi.
CN106983733A (zh) * 2017-03-08 2017-07-28 江苏富泽药业有限公司 曲安奈德plga缓释微球注射剂、其制备方法及其在制备治疗骨关节炎疼痛药物中的应用
KR20190038368A (ko) 2017-09-29 2019-04-08 주식회사 엘지화학 히알루론산 기반 하이드로겔 약제학적 안정화 조성물 및 그 제조방법
CN118021719A (zh) * 2022-11-11 2024-05-14 北京华视诺维医疗科技有限公司 一种曲安奈德组合物及其制备方法
WO2025068242A1 (en) * 2023-09-25 2025-04-03 Hyamedix Dexamethasone delivery system

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SE442820B (sv) 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
US4582865A (en) 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
SE8501022L (sv) 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
US4713448A (en) 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1198449B (it) 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
US4866050A (en) 1988-04-27 1989-09-12 Ben Amoz Daniel Ultrasonic transdermal application of steroid compositions
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
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US5207983A (en) * 1992-01-29 1993-05-04 Sterling Winthrop Inc. Method of terminal steam sterilization
IT1260154B (it) 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
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US5621093A (en) 1995-06-06 1997-04-15 Anika Research, Inc. Steam-sterilizing solid hyaluronic acid
US5827937A (en) 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
TW577758B (en) 1997-10-27 2004-03-01 Ssp Co Ltd Intra-articular preparation for the treatment of arthropathy
SE9704186D0 (sv) 1997-11-14 1997-11-14 Astra Ab New composition of matter
US6066292A (en) 1997-12-19 2000-05-23 Bayer Corporation Sterilization process for pharmaceutical suspensions
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
US6726918B1 (en) * 2000-07-05 2004-04-27 Oculex Pharmaceuticals, Inc. Methods for treating inflammation-mediated conditions of the eye
ATE392907T1 (de) 2000-07-28 2008-05-15 Anika Therapeutics Inc Bioabsorbierbare kompositmaterialien aus derivatisierter hyaluronsäure
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
BR0115584A (pt) 2000-11-24 2003-09-23 Breath Ltd Esterilização de produtos farmacêuticos
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US20060141049A1 (en) 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
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Also Published As

Publication number Publication date
BR112012005423B1 (pt) 2022-09-13
CN102573468B (zh) 2015-05-20
EP2475251A4 (en) 2012-10-24
WO2011031402A1 (en) 2011-03-17
BR112012005423A2 (pt) 2017-07-04
EP3622820B1 (en) 2026-02-18
JP2013504570A (ja) 2013-02-07
JP2015172095A (ja) 2015-10-01
EP3622820A1 (en) 2020-03-18
US20110059918A1 (en) 2011-03-10
CN102573468A (zh) 2012-07-11
MX2012002830A (es) 2012-04-10
US8680073B2 (en) 2014-03-25
US20120316131A1 (en) 2012-12-13
EP2475251B1 (en) 2019-07-17
JP6121717B2 (ja) 2017-04-26
EP2475251A1 (en) 2012-07-18
US8273725B2 (en) 2012-09-25

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