AR076596A1 - Medicamento para la administracion oral que contiene al menos un estrogeno y/o al menos un gestageno y al menos una cepa de bacterias probioticas - Google Patents

Medicamento para la administracion oral que contiene al menos un estrogeno y/o al menos un gestageno y al menos una cepa de bacterias probioticas

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Publication number
AR076596A1
AR076596A1 ARP100101772A ARP100101772A AR076596A1 AR 076596 A1 AR076596 A1 AR 076596A1 AR P100101772 A ARP100101772 A AR P100101772A AR P100101772 A ARP100101772 A AR P100101772A AR 076596 A1 AR076596 A1 AR 076596A1
Authority
AR
Argentina
Prior art keywords
microg
gestagen
probiotic bacteria
strain
daily dose
Prior art date
Application number
ARP100101772A
Other languages
English (en)
Inventor
Stefanie Lindemann
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of AR076596A1 publication Critical patent/AR076596A1/es

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente se refiere a un medicamento para la administracion oral que contiene al menos un estrogeno y/o un gestágeno así como al menos una cepa de bacterias probioticas, como, por ejemplo, especies de lactobacilos. El medicamento se usa ya sea para la anticoncepcion oral o para la terapia hormonal (HT) , en donde es, en este caso, puede servir al mismo tiempo para la estabilizacion del ambiente vaginal y, con ello, para la prevencion de enfermedades infecciosas, tales como, por ejemplo, micosis vaginales, vaginosis bacterianas y/o inflamaciones de la vejiga (cistitis bacterianas) o la prevencion de síntomas urogenitales, por ejemplo, dispareunia y disuria. La presente se refiere también a composiciones farmacéuticas, a las unidades de dosis que contienen un medicamento descrito previamente, así como otras unidades de dosis que contienen exclusivamente una cepa de bacterias probioticas. Reivindicacion 7: Medicamento de acuerdo con la reivindicacion 1, caracterizado porque como dosis diaria de un gestágeno están contenidos: drospirenona 0,5 - 5 mg, levonorgestrel 30 - 250 microg, norgestimato 180 - 250 microg, acetato de noretisterona 0,5 - 1 mg, acetato de ciproterona 1 - 2 mg, desogestrel 20 - 150 microg, dienogest 1 - 3 mg, gestodeno 60 - 75 microg, tibolona 2,5 mg. Reivindicacion 9: Medicamento de acuerdo con la reivindicacion 1, caracterizado porque como dosis diaria de un estrogeno están contenidos: etinilestradiol 10 - 50 microg, estradiol 1 - 4 mg, valerato de estradiol 1 - 4 mg, mestranol 50 microg. Reivindicacion 11: Medicamento de acuerdo con la reivindicacion 1, caracterizado porque como dosis diaria de cepa de bacterias prebiotica están contenidas 109 a 1011 KBE (Kolonie Bildende Einheiten, 'unidades formadoras de colonias').
ARP100101772A 2009-05-22 2010-05-21 Medicamento para la administracion oral que contiene al menos un estrogeno y/o al menos un gestageno y al menos una cepa de bacterias probioticas AR076596A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009022947 2009-05-22
DE102009023632 2009-05-27

Publications (1)

Publication Number Publication Date
AR076596A1 true AR076596A1 (es) 2011-06-22

Family

ID=42617521

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100101772A AR076596A1 (es) 2009-05-22 2010-05-21 Medicamento para la administracion oral que contiene al menos un estrogeno y/o al menos un gestageno y al menos una cepa de bacterias probioticas

Country Status (9)

Country Link
US (1) US20120189599A1 (es)
EP (1) EP2432474A1 (es)
JP (1) JP2012527413A (es)
CN (1) CN102438628A (es)
AR (1) AR076596A1 (es)
CA (1) CA2762640A1 (es)
TW (1) TW201109019A (es)
UY (1) UY32650A (es)
WO (1) WO2010133314A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2992861B1 (fr) 2012-07-09 2014-10-17 Probionov Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles
CN104178437B (zh) * 2013-11-08 2016-08-24 苏州欧赛微科生物医药科技有限公司 一种卷曲乳杆菌及其在妇科疾病中的应用
CN104546870B (zh) * 2015-01-27 2018-01-12 唐凡兰 一种避孕药
KR101867768B1 (ko) 2016-08-12 2018-06-15 한국식품연구원 락토바실러스 아시도필루스를 포함하는 갱년기 예방 또는 치료용 조성물
EP3427745A1 (en) 2017-07-12 2019-01-16 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO New probiotic composition for prevention of bacterial vaginosis
JP2021513507A (ja) * 2018-02-07 2021-05-27 エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ 心臓血管系への影響を低減した避妊薬組成物
KR102107443B1 (ko) * 2018-08-31 2020-05-07 (주)바이오리듬 여성 갱년기 증상 예방 또는 치료용 유산균 프로바이오틱스 제제
KR20220026201A (ko) * 2020-08-25 2022-03-04 고려대학교 산학협력단 락토바실러스 퍼멘텀을 포함하는 갱년기 예방 또는 치료용 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4905300A (en) * 1999-05-25 2000-12-12 Andrew W. Bruce Oral administration of lactobacillus for the maintenance of health in women
KR100400411B1 (ko) * 2000-09-09 2003-10-01 주식회사 바이오프로젠 질염 치료용 생균제제
WO2003082306A1 (en) * 2002-03-28 2003-10-09 Gregor Reid Lactobacillus iners for the enhancement of urogenital health
US7759105B2 (en) * 2003-08-29 2010-07-20 Cobb & Company, Llp Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
CN101028289A (zh) * 2006-03-01 2007-09-05 大连森佰澳科技有限公司 调整菌群预防或治疗细菌性阴道病的益生菌制剂及工艺

Also Published As

Publication number Publication date
UY32650A (es) 2010-12-31
CA2762640A1 (en) 2010-11-25
JP2012527413A (ja) 2012-11-08
TW201109019A (en) 2011-03-16
EP2432474A1 (de) 2012-03-28
CN102438628A (zh) 2012-05-02
WO2010133314A1 (de) 2010-11-25
US20120189599A1 (en) 2012-07-26

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