AR073034A1 - Composiciones mucoadherentes y sus usos - Google Patents
Composiciones mucoadherentes y sus usosInfo
- Publication number
- AR073034A1 AR073034A1 ARP090103119A ARP090103119A AR073034A1 AR 073034 A1 AR073034 A1 AR 073034A1 AR P090103119 A ARP090103119 A AR P090103119A AR P090103119 A ARP090103119 A AR P090103119A AR 073034 A1 AR073034 A1 AR 073034A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition according
- polymer
- mucoadherent
- bioadherent
- active principle
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente solicitud contempla la provision de composiciones mucoadherentes con propiedades mejoradas de bioadhesividad, consistencia, estabilidad y de regulacion del pH vaginal, pudiendo también ser portadora de un principio activo para el tratamiento o profilaxis de trastornos o dolencias causados en las mucosas, particularmente en el tracto vaginal, así como también sus usos. Reivindicacion 1: Composicion mucoadherente, caracterizada porque está esencialmente exenta de sustancias oleosas y comprende: (a) 0,25 a 1,5% de un polímero bioadherente; (b) 0,25 a 1,5% de un polímero gelificante, o (c) 17 a 25% de excipientes farmacéuticamente aceptables; y (d) agua; con la condicion de que la proporcion del polímero bioadherente con respecto al polímero gelificante sea de 1:1. Reivindicacion 6: Composicion de acuerdo con la reivindicacion 1, caracterizada porque el polímero bioadherente es policarbofilo. Reivindicacion 7: Composicion de acuerdo con la reivindicacion 1, caracterizada porque el polímero gelificante es un polímero poliacrílico del tipo carbomero. Reivindicacion 22: Composicion de acuerdo con la reivindicacion 17, caracterizada porque dicho principio activo es una hormona seleccionada del grupo que consiste de estrogenos y progestogenos. Reivindicacion 23: Composicion de acuerdo con la reivindicacion 17, caracterizada porque dicho principio activo es un antibacteriano. Reivindicacion 24: Composicion de acuerdo con las reivindicaciones 17 o 23, caracterizada porque el antibacteriano es seleccionado del grupo que consiste de clindamicina, penicilinas, cefalosporinas, tetraciclinas, gentamicina, eritromicina, canamicina, estreptomicina. Reivindicacion 25: Composicion de acuerdo con la reivindicacion 17 caracterizada porque dicho principio activo es un antimicotico y/o antiprotozoario. Reivindicacion 27: Composicion de acuerdo con la reivindicacion 17, caracterizada porque dicho principio activo es un antiviral.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0803568A BRPI0803568B8 (pt) | 2008-08-14 | 2008-08-14 | composição mucoaderente |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR073034A1 true AR073034A1 (es) | 2010-10-06 |
Family
ID=41668595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090103119A AR073034A1 (es) | 2008-08-14 | 2009-08-12 | Composiciones mucoadherentes y sus usos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20110218166A1 (es) |
| EP (1) | EP2328550A4 (es) |
| JP (1) | JP2011530541A (es) |
| KR (1) | KR20110050511A (es) |
| CN (1) | CN102170860A (es) |
| AR (1) | AR073034A1 (es) |
| AU (1) | AU2009281647A1 (es) |
| BR (1) | BRPI0803568B8 (es) |
| CA (1) | CA2733724A1 (es) |
| CO (1) | CO6341543A2 (es) |
| IL (1) | IL211204A0 (es) |
| MX (1) | MX2011001739A (es) |
| RU (1) | RU2011109393A (es) |
| WO (1) | WO2010017614A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100158821A1 (en) * | 2008-12-22 | 2010-06-24 | Eastman Chemical Company | Antimicrobial agents, compositions and products containing the same, and methods of using the compositions and products |
| US20110028566A1 (en) * | 2009-05-15 | 2011-02-03 | Eastman Chemical Company | Compositions and products containing cycloaliphatic diol antimicrobial agents and methods of using the compositions and products |
| SI23309A (sl) * | 2010-03-22 | 2011-09-30 | Kemijski inštitut | Kombinacija protiglivne substance in motilca znotrajcelične protonske homeostaze za uničevanje ali inhibicijo rasti in replikacije gliv |
| CN102293735B (zh) * | 2011-08-19 | 2013-05-01 | 辽宁万嘉医药科技有限公司 | 一种抗真菌咪唑类药物缓释凝胶和制备方法 |
| EP2861215A4 (en) * | 2012-06-13 | 2015-04-22 | Evofem Inc | COMPOSITIONS AND METHODS FOR INCREASING THE EFFECTIVENESS OF RECIPROCAL MICROBICIDES |
| EP3025709B1 (en) * | 2014-11-27 | 2020-09-30 | Capsugel Belgium NV | Dosage form articles for external mucosal applications |
| KR101882820B1 (ko) * | 2015-12-30 | 2018-07-30 | 주식회사 삼양바이오팜 | 점막부착성 약학 조성물 및 그의 제조방법 |
| CN106265486A (zh) * | 2016-08-18 | 2017-01-04 | 滨州医学院附属医院 | 一种硝酸咪康唑缓释凝胶及其制备方法 |
| US20230346724A1 (en) * | 2018-10-09 | 2023-11-02 | Crapaud Bio Inc. | Methods of Making and Using pH Modulating Compositions in the Reproductive System |
| CN110575431B (zh) * | 2019-08-28 | 2021-08-03 | 南京天朗制药有限公司 | 一种阴道酸碱缓冲凝胶及制备方法 |
| CN112933109A (zh) * | 2021-02-03 | 2021-06-11 | 湖南奥朗特医疗器械有限公司 | 一种阴道pH调节剂及其制备方法和应用 |
| CN113940915B (zh) * | 2021-12-07 | 2024-04-26 | 南京麦澜德医疗科技股份有限公司 | 一种阴道内用凝胶及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69819748T2 (de) * | 1997-09-12 | 2004-09-30 | Columbia Laboratories (Bermuda) Ltd. | Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen |
| US7803392B2 (en) * | 2000-12-27 | 2010-09-28 | University Of Kentucky Research Foundation | pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules |
| US20030114394A1 (en) * | 2001-10-29 | 2003-06-19 | Levine Howard L. | Vaginally administered anti-dysrhythmic agents for treating pelvic pain |
| ES2237298B1 (es) * | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
| WO2008027037A1 (en) * | 2006-08-29 | 2008-03-06 | University Of Kentucky Research Foundation | Compositions and methods for oral cancer chemoprevention using berry preparations and extracts |
-
2008
- 2008-08-14 BR BRPI0803568A patent/BRPI0803568B8/pt active IP Right Grant
-
2009
- 2009-08-12 AR ARP090103119A patent/AR073034A1/es unknown
- 2009-08-14 EP EP09806251.6A patent/EP2328550A4/en not_active Withdrawn
- 2009-08-14 US US13/059,032 patent/US20110218166A1/en not_active Abandoned
- 2009-08-14 KR KR1020117005724A patent/KR20110050511A/ko not_active Application Discontinuation
- 2009-08-14 AU AU2009281647A patent/AU2009281647A1/en not_active Abandoned
- 2009-08-14 JP JP2011522354A patent/JP2011530541A/ja not_active Withdrawn
- 2009-08-14 WO PCT/BR2009/000255 patent/WO2010017614A1/en active Application Filing
- 2009-08-14 CN CN2009801388153A patent/CN102170860A/zh active Pending
- 2009-08-14 CA CA2733724A patent/CA2733724A1/en not_active Abandoned
- 2009-08-14 MX MX2011001739A patent/MX2011001739A/es not_active Application Discontinuation
- 2009-08-14 RU RU2011109393/15A patent/RU2011109393A/ru unknown
-
2011
- 2011-02-13 IL IL211204A patent/IL211204A0/en unknown
- 2011-02-23 CO CO11022141A patent/CO6341543A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2328550A1 (en) | 2011-06-08 |
| WO2010017614A1 (en) | 2010-02-18 |
| AU2009281647A1 (en) | 2010-02-18 |
| US20110218166A1 (en) | 2011-09-08 |
| CN102170860A (zh) | 2011-08-31 |
| CA2733724A1 (en) | 2010-02-18 |
| JP2011530541A (ja) | 2011-12-22 |
| RU2011109393A (ru) | 2012-09-20 |
| BRPI0803568B1 (pt) | 2020-10-13 |
| MX2011001739A (es) | 2011-07-05 |
| EP2328550A4 (en) | 2013-11-20 |
| BRPI0803568B8 (pt) | 2021-05-25 |
| KR20110050511A (ko) | 2011-05-13 |
| CO6341543A2 (es) | 2011-11-21 |
| IL211204A0 (en) | 2011-04-28 |
| BRPI0803568A2 (pt) | 2010-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |