AR072444A1 - Metodo para confirmar la actividad antioxidante de una composicion topica - Google Patents

Metodo para confirmar la actividad antioxidante de una composicion topica

Info

Publication number
AR072444A1
AR072444A1 ARP090100208A ARP090100208A AR072444A1 AR 072444 A1 AR072444 A1 AR 072444A1 AR P090100208 A ARP090100208 A AR P090100208A AR P090100208 A ARP090100208 A AR P090100208A AR 072444 A1 AR072444 A1 AR 072444A1
Authority
AR
Argentina
Prior art keywords
extract
composition according
composition
skin
induced
Prior art date
Application number
ARP090100208A
Other languages
English (en)
Original Assignee
Schering Plough Healthcare
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Healthcare filed Critical Schering Plough Healthcare
Publication of AR072444A1 publication Critical patent/AR072444A1/es

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Abstract

Métodos para confirmar actividad antioxidante de una composicion formulada para aplicacion topica a la piel. Métodos para probar una composicion para la capacidad de inhibir la formacion de peroxidacion de lípidos inducida por radiacion ultravioleta en la piel como la formacion de especies de oxígeno reactivo inducido por radiacion ultravioleta en la epidermis. Composiciones. Métodos para tratar y prevenir fotodano de la piel. Reivindicacion 4: El método de conformidad con la reivindicacion 2, caracterizado porque la determinacion de la inhibicion de formacion de hidroperoxidos de lípidos en la piel inducida por UVR comprende determinar el porcentaje de inhibicion de hidroperoxidos de lípidos del compuesto en comparacion con el placebo. Reivindicacion 9: La composicion de conformidad con la reivindicacion 8, caracterizada porque además comprende al menos un agente activo de filtro solar. Reivindicacion 10: La composicion de conformidad con la reivindicacion 9, caracterizada porque el agente activo de filtro solar se elige del grupo que consiste de ácido para-aminobenzoico, avobenzona, cinoxato, dioxibenzona, homosalato, antranilato de metilo, salicitato de octilo, oxibenzona, padimato O, ácido fenilbenzimidazol sulfonico, sulisobenzona, salicilato de trolamina, dioxido de titanio, oxido de zinc, metoxicinamato de dietanolamina, trioleato de digaloi, etil dihidroxipropilo PABA, aminobenzoato de glicerilo, lawsona con dihidroxiacetona, petrolato rojo, triazona de etilhexilo, butamido triazona de dioctilo, bencilideno malonato polisiloxano, ácido tereftalilideno dicanfor sulfonico, tetrasulfonato de disodio fenil dibenzimidazol, benzoato de dietilamino hidroxibenzoil hexil, bis dietilamino hidroxibenzoil benzoato, bis benzoxazoilfenil etilhexilimino triazina, trisiloxano de drometrizol, metilen bis-benzotriazolil tetrametilbutilfenol, y bis-etilhexiloxifenol metoxifeniltriazina, 4-metilbencilidencanfor, e isopetil 4-metoxicinamato y mezclas de los mismos. Reivindicacion 13: La composicion de conformidad con la reivindicacion 8, caracterizada porque comprende como un antioxidante Vitamina E y al menos un compuesto antioxidante adicional. Reivindicacion 16: La composicion de conformidad con la reivindicacion 13, caracterizada porque al menos un compuesto antioxidante adicional se elige del grupo que consiste de malonato de dietilhexil siringlideno, malonato de diisopropil vanilideno, tetrahidrocurcumenoides, fermentado de zimbiozona de fríjol de soya, extracto de trébol rojo, extracto de semilla de Vitis vinífera (uva) / Clase B, extracto de té verde, extracto de Pikea robusta, tocoferol (y) extracto de semilla de Vitis vinífera (uva), extracto de semilla de Vitis vinífera (uva) / Clase A, extracto de fruta Phylanthus emblica y combinaciones de los mismos. Reivindicacion 17: Una composicion para aplicacion topica, caracterizada porque la composicion comprende Vitamina E y al menos un compuesto pro-oxidante, en donde la combinacion de Vitamina E y el compuesto pro-oxidante inhibe substancialmente la formacion tanto de peroxidacion de lípido en la piel inducida por radiacion ultravioleta como de especies de oxígeno reactivo inducido por radiacion ultravioleta en la epidermis. Reivindicacion 18: La composicion de conformidad con la reivindicacion 17, caracterizado porque al menos un compuesto pro-oxidante se elige del grupo que consiste de Oleoresina de romero officinalis, extracto de Rosa Gallica, complejo fotosintético bioactivo de plantas verdes, fermentado de Thermus Thermophillus, ergotiotaina y combinaciones de los mismos. Reivindicacion 21: La composicion de conformidad con la reivindicacion 17, caracterizada porque comprende además malonato de dietilhexil siringlideno.
ARP090100208A 2008-01-25 2009-01-23 Metodo para confirmar la actividad antioxidante de una composicion topica AR072444A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2371308P 2008-01-25 2008-01-25
US11475808P 2008-11-14 2008-11-14

Publications (1)

Publication Number Publication Date
AR072444A1 true AR072444A1 (es) 2010-09-01

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ID=40427148

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090100208A AR072444A1 (es) 2008-01-25 2009-01-23 Metodo para confirmar la actividad antioxidante de una composicion topica

Country Status (13)

Country Link
US (4) US20090189090A1 (es)
EP (1) EP2247949B1 (es)
JP (2) JP2011511770A (es)
CN (2) CN103394088B (es)
AR (1) AR072444A1 (es)
AU (1) AU2009206489B2 (es)
BR (1) BRPI0908478A2 (es)
CA (1) CA2711270C (es)
ES (1) ES2637516T3 (es)
HR (1) HRP20171215T1 (es)
MX (1) MX2010008065A (es)
PT (1) PT2247949T (es)
WO (1) WO2009094374A2 (es)

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Also Published As

Publication number Publication date
PT2247949T (pt) 2017-08-25
US9096882B2 (en) 2015-08-04
MX2010008065A (es) 2010-10-20
CN103394088B (zh) 2017-01-18
EP2247949A2 (en) 2010-11-10
US20190285657A1 (en) 2019-09-19
HRP20171215T1 (hr) 2017-12-15
JP2015163624A (ja) 2015-09-10
US20090189090A1 (en) 2009-07-30
CN101925816A (zh) 2010-12-22
US20160033538A1 (en) 2016-02-04
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CA2711270C (en) 2017-02-28
JP2011511770A (ja) 2011-04-14
AU2009206489B2 (en) 2014-10-02
US20130101515A1 (en) 2013-04-25
CN103394088A (zh) 2013-11-20
EP2247949B1 (en) 2017-05-24
WO2009094374A3 (en) 2009-09-17
ES2637516T3 (es) 2017-10-13
CA2711270A1 (en) 2009-07-30
BRPI0908478A2 (pt) 2015-08-18
WO2009094374A2 (en) 2009-07-30
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AU2009206489A1 (en) 2009-07-30

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